@article {pmid32945570,
year = {2020},
author = {Bryant, PA and Rogers, BA and Cowan, R and Bowen, AC and Pollard, J and , },
title = {Planning and clinical role of acute medical home care services for COVID-19: consensus position statement by the Hospital-in-the-Home Society Australasia.},
journal = {Internal medicine journal},
volume = {50},
number = {10},
pages = {1267-1271},
pmid = {32945570},
issn = {1445-5994},
mesh = {Australasia/epidemiology ; Betacoronavirus ; COVID-19 ; Communication ; Coronavirus Infections/*epidemiology/*therapy ; Equipment and Supplies, Hospital/supply & distribution ; Health Workforce/organization & administration ; Home Care Services/*organization & administration ; Humans ; Infection Control/organization & administration ; Occupational Exposure/prevention & control ; Pandemics ; Patient-Centered Care/organization & administration ; Pneumonia, Viral/*epidemiology/*therapy ; SARS-CoV-2 ; Workload ; },
abstract = {During a pandemic when hospitals are stretched and patients need isolation, the role of hospital-in-the-home (HITH) providing acute medical care at home has never been more relevant. We aimed to define and address the challenges to acute home care services posed by the COVID-19 pandemic. Planning for service operation involves staffing, equipment availability and cleaning, upskilling in telehealth and communication. Planning for clinical care involves maximising cohorts of patients without COVID-19 and new clinical pathways for patients with COVID-19. The risk of SARS-CoV-2 transmission, specific COVID-19 clinical pathways and the well-being of patients and staff should be addressed in advance.},
}

Australasia/epidemiology
Betacoronavirus
COVID-19
Communication
Coronavirus Infections/*epidemiology/*therapy
Equipment and Supplies, Hospital/supply & distribution
Health Workforce/organization & administration
Home Care Services/*organization & administration
Humans
Infection Control/organization & administration
Occupational Exposure/prevention & control
Pandemics
Patient-Centered Care/organization & administration
Pneumonia, Viral/*epidemiology/*therapy
SARS-CoV-2
Workload

@article {pmid32941344,
year = {2020},
author = {Oliva, A and Caputo, M and Grassi, S and Vetrugno, G and Marazza, M and Ponzanelli, G and Cauda, R and Scambia, G and Forti, G and Bellantone, R and Pascali, VL},
title = {Liability of Health Care Professionals and Institutions During COVID-19 Pandemic in Italy: Symposium Proceedings and Position Statement.},
journal = {Journal of patient safety},
volume = {16},
number = {4},
pages = {e299-e302},
pmid = {32941344},
issn = {1549-8425},
mesh = {Betacoronavirus/isolation & purification ; COVID-19 ; Coronavirus Infections/epidemiology ; Health Personnel/*legislation & jurisprudence ; Humans ; Italy/epidemiology ; *Legislation, Hospital ; *Liability, Legal ; Pandemics/*legislation & jurisprudence ; Pneumonia, Viral/epidemiology ; SARS-CoV-2 ; },
abstract = {BACKGROUND: On May 12, 2020, a symposium titled "Liability of healthcare professionals and institutions during COVID-19 pandemic" was held in Italy with the participation of national experts in malpractice law, hospital management, legal medicine, and clinical risk management. The symposium's rationale was the highly likely inflation of criminal and civil proceedings concerning alleged errors committed by health care professionals and decision makers during the COVID-19 pandemic. Its aim was to identify and discuss the main issues of legal and medicolegal interest and thus to find solid solutions in the spirit of preparedness planning.

METHODS: There were 5 main points of discussion: (A) how to judge errors committed during the pandemic because of the application of protocols and therapies based on no or weak evidence of efficacy, (B) whether hospital managers can be considered liable for infected health care professionals who were not given adequate personal protective equipment, (C) whether health care professionals and institutions can be considered liable for cases of infected inpatients who claim that the infection was transmitted in a hospital setting, (D) whether health care institutions and hospital managers can be considered liable for the hotspots in long-term care facilities/care homes, and (E) whether health care institutions and hospital managers can be considered liable for the worsening of chronic diseases.

RESULTS AND CONCLUSION: Limitation of the liability to the cases of gross negligence (with an explicit definition of this term), a no-fault system with statal indemnities for infected cases, and a rigorous methodology for the expert witnesses were proposed as key interventions for successfully facing future proceedings.},
}

Betacoronavirus/isolation & purification
COVID-19
Coronavirus Infections/epidemiology
Health Personnel/*legislation & jurisprudence
Humans
Italy/epidemiology
*Legislation, Hospital
*Liability, Legal
Pandemics/*legislation & jurisprudence
Pneumonia, Viral/epidemiology
SARS-CoV-2

@article {pmid32933562,
year = {2020},
author = {Villani, A and Bozzola, E and Staiano, A and Agostiniani, R and Del Vecchio, A and Zamperini, N and Marino, F and Vecchio, D and Corsello, G},
title = {Facial masks in children: the position statement of the Italian pediatric society.},
journal = {Italian journal of pediatrics},
volume = {46},
number = {1},
pages = {132},
pmid = {32933562},
issn = {1824-7288},
mesh = {*Betacoronavirus ; COVID-19 ; Child ; *Consensus ; Coronavirus Infections/epidemiology/*transmission ; Disease Transmission, Infectious/*prevention & control ; Equipment Design ; Humans ; Infection Control/*organization & administration ; Masks/standards/*supply & distribution ; Pandemics ; Pneumonia, Viral/epidemiology/*transmission ; SARS-CoV-2 ; },
abstract = {Facial masks may be one of the most cost-effective strategies to prevent the diffusion of COVID 19 infection. Nevertheless, fake news are spreading, alerting parents on dangerous side effects in children, such as hypercapnia, hypoxia, gut dysbiosis and immune system weakness. Aim of the Italian Pediatric Society statement is to face misconception towards the use of face masks and to spread scientific trustable information.},
}

*Betacoronavirus
COVID-19
Child
*Consensus
Coronavirus Infections/epidemiology/*transmission
Disease Transmission, Infectious/*prevention & control
Equipment Design
Humans
Infection Control/*organization & administration
Masks/standards/*supply & distribution
Pandemics
Pneumonia, Viral/epidemiology/*transmission
SARS-CoV-2

@article {pmid32890777,
year = {2020},
author = {Greenspan, H and San José Estépar, R and Niessen, WJ and Siegel, E and Nielsen, M},
title = {Position paper on COVID-19 imaging and AI: From the clinical needs and technological challenges to initial AI solutions at the lab and national level towards a new era for AI in healthcare.},
journal = {Medical image analysis},
volume = {66},
number = {},
pages = {101800},
pmid = {32890777},
issn = {1361-8423},
support = {R01 HL149877/HL/NHLBI NIH HHS/United States ; R21 HL140422/HL/NHLBI NIH HHS/United States ; },
mesh = {Algorithms ; Artificial Intelligence/*trends ; Betacoronavirus ; COVID-19 ; Coronavirus Infections/*diagnostic imaging ; Diagnostic Imaging/*methods ; Humans ; Pandemics ; Pneumonia, Viral/*diagnostic imaging ; SARS-CoV-2 ; },
abstract = {In this position paper, we provide a collection of views on the role of AI in the COVID-19 pandemic, from clinical requirements to the design of AI-based systems, to the translation of the developed tools to the clinic. We highlight key factors in designing system solutions - per specific task; as well as design issues in managing the disease at the national level. We focus on three specific use-cases for which AI systems can be built: early disease detection, management in a hospital setting, and building patient-specific predictive models that require the combination of imaging with additional clinical data. Infrastructure considerations and population modeling in two European countries will be described. This pandemic has made the practical and scientific challenges of making AI solutions very explicit. A discussion concludes this paper, with a list of challenges facing the community in the AI road ahead.},
}

Algorithms
Artificial Intelligence/*trends
Betacoronavirus
COVID-19
Coronavirus Infections/*diagnostic imaging
Diagnostic Imaging/*methods
Humans
Pandemics
Pneumonia, Viral/*diagnostic imaging
SARS-CoV-2

@article {pmid32882035,
year = {2020},
author = {Rutkowski, JL and Camm, DP and El Chaar, E},
title = {AAID White Paper: Management of the Dental Implant Patient During the COVID-19 Pandemic and Beyond.},
journal = {The Journal of oral implantology},
volume = {46},
number = {5},
pages = {454-466},
doi = {10.1563/aaid-joi-D-20-00316},
pmid = {32882035},
issn = {0160-6972},
mesh = {*Betacoronavirus ; *COVID-19 ; *Dental Implants ; Humans ; Pandemics ; United States ; },
abstract = {The scientific community's understanding of how the SARS-CoV-2 virus is transmitted and how to best mitigate its spread is improving daily. To help protect patients from acquiring COVID-19 from a dental office nosocomial infection, many state or local governments have classified dental treatments as "nonessential" and have paused routine dental care. Dentists have been instructed to perform only procedures designated as emergencies. Unfortunately, there is not a good understanding of what a dental emergency is among governmental leaders. What a government agency may perceive as an elective procedure may be seen as "essential" by the dental clinician responsible for maintaining the oral health of the patient. Each dental specialty understands the effects delayed care has on a patient's oral and systemic health. Dentistry has made extensive progress in improving oral health through prevention of the dental emergency. The dental profession must work together to prevent the reversal of the progress dentistry and patients have made. This American Academy of Implant Dentistry (AAID) White Paper discusses what COVID-19 is and how it impacts dental treatments, presents guidelines for dentistry in general and for dental implant related treatments, specifically. Recommendations for implant dentistry include the following: (1) what constitutes a dental implant related emergency, (2) how patients should be screened and triaged, (3) what personal protective equipment is necessary, (4) how operatories should be equipped, (5) what equipment should be used, and (6) what, when, and how procedures can be performed. This paper is intended to provide guidance for the dental implant practice so patients and dental health care providers can be safe, and offices can remain open and viable during the pandemic.},
}

*Betacoronavirus
*COVID-19
*Dental Implants
Humans
Pandemics
United States

@article {pmid32876200,
year = {2020},
author = {Soeiro, AM and Leal, TCAT and Pereira, MP and Lima, EG and Figueiredo, ACBDS and Petriz, JLF and Precoma, DB and Serrano, CV},
title = {Position Statement on the Use of Antiplatelet Agents and Anticoagulants in Patients Infected with the New Coronavirus (COVID-19) - 2020.},
journal = {Arquivos brasileiros de cardiologia},
volume = {115},
number = {2},
pages = {292-301},
pmid = {32876200},
issn = {1678-4170},
mesh = {Anticoagulants/*therapeutic use ; Betacoronavirus ; COVID-19 ; Coronavirus Infections/*drug therapy ; Humans ; Pandemics ; Platelet Aggregation Inhibitors/*therapeutic use ; Pneumonia, Viral/*drug therapy ; SARS-CoV-2 ; },
}

Anticoagulants/*therapeutic use
Betacoronavirus
COVID-19
Coronavirus Infections/*drug therapy
Humans
Pandemics
Platelet Aggregation Inhibitors/*therapeutic use
Pneumonia, Viral/*drug therapy
SARS-CoV-2

@article {pmid32871013,
year = {2020},
author = {Noel, JM and Jackson, CW},
title = {ASHP Therapeutic Position Statement on the Use of Antipsychotic Medications in the Treatment of Adults with Schizophrenia and Schizoaffective Disorder.},
journal = {American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists},
volume = {77},
number = {24},
pages = {2114-2132},
doi = {10.1093/ajhp/zxaa303},
pmid = {32871013},
issn = {1535-2900},
mesh = {Adult ; Antipsychotic Agents/*administration & dosage/adverse effects ; Humans ; Psychotic Disorders/*drug therapy ; Schizophrenia/*drug therapy ; Societies, Pharmaceutical ; United States ; },
abstract = {In an effort to expedite the publication of articles related to the COVID-19 pandemic, AJHP is posting these manuscripts online as soon as possible after acceptance. Accepted manuscripts have been peer-reviewed and copyedited, but are posted online before technical formatting and author proofing. These manuscripts are not the final version of record and will be replaced with the final article (formatted per AJHP style and proofed by the authors) at a later time.},
}

Adult
Antipsychotic Agents/*administration & dosage/adverse effects
Humans
Psychotic Disorders/*drug therapy
Schizophrenia/*drug therapy
Societies, Pharmaceutical
United States

@article {pmid32825892,
year = {2020},
author = {Vora, A and Arora, VK and Behera, D and Tripathy, SK},
title = {White paper on Ivermectin as a potential therapy for COVID-19.},
journal = {The Indian journal of tuberculosis},
volume = {67},
number = {3},
pages = {448-451},
pmid = {32825892},
issn = {0019-5707},
mesh = {Antiparasitic Agents/therapeutic use ; *Betacoronavirus ; COVID-19 ; Coronavirus Infections/*drug therapy ; Humans ; Ivermectin/*therapeutic use ; Pandemics ; Pneumonia, Viral/*drug therapy ; Risk Factors ; SARS-CoV-2 ; Treatment Outcome ; },
abstract = {A group of senior doctors with vast clinical experience met on 19th July'20 under the aegis of Academy of Advanced Medical Education. The panel looked at Ivermectin, one of the old molecule and evaluated it's use in COVID 19 (Novel Coronavirus Disease 2019) management. After critical panel discussion, all the attending doctors came to a conclusion that Ivermectin can be a potential molecule for prophylaxis and treatment of people infected with Coronavirus, owing to its anti-viral properties coupled with effective cost, availability and good tolerability and safety.},
}

Antiparasitic Agents/therapeutic use
*Betacoronavirus
COVID-19
Coronavirus Infections/*drug therapy
Humans
Ivermectin/*therapeutic use
Pandemics
Pneumonia, Viral/*drug therapy
Risk Factors
SARS-CoV-2
Treatment Outcome

@article {pmid32823368,
year = {2020},
author = {Pfaar, O and Klimek, L and Worm, M and Bergmann, KC and Bieber, T and Buhl, R and Buters, J and Darsow, U and Keil, T and Kleine-Tebbe, J and Lau, S and Maurer, M and Merk, H and Mösges, R and Saloga, J and Staubach, P and Stute, P and Rabe, K and Rabe, U and Vogelmeier, C and Biedermann, T and Jung, K and Schlenter, W and Ring, J and Chaker, A and Wehrmann, W and Becker, S and Mülleneisen, N and Nemat, K and Czech, W and Wrede, H and Brehler, R and Fuchs, T and Tomazic, PV and Aberer, W and Fink-Wagner, A and Horak, F and Wöhrl, S and Niederberger-Leppin, V and Pali-Schöll, I and Pohl, W and Roller-Wirnsberger, R and Spranger, O and Valenta, R and Akdis, M and Akdis, C and Hoffmann-Sommergruber, K and Jutel, M and Matricardi, P and Spertini, F and Khaltaev, N and Michel, JP and Nicod, L and Schmid-Grendelmeier, P and Hamelmann, E and Jakob, T and Werfel, T and Wagenmann, M and Taube, C and Gerstlauer, M and Vogelberg, C and Bousquet, J and Zuberbier, T},
title = {[Handling of allergen immunotherapy in the COVID-19 pandemic: An ARIA-EAACI-AeDA-GPA-DGAKI Position Paper (Pocket-Guide)].},
journal = {Laryngo- rhino- otologie},
volume = {99},
number = {10},
pages = {676-679},
doi = {10.1055/a-1170-8426},
pmid = {32823368},
issn = {1438-8685},
mesh = {*Betacoronavirus ; COVID-19 ; *Coronavirus Infections ; Desensitization, Immunologic ; Humans ; *Pandemics ; *Pneumonia, Viral ; SARS-CoV-2 ; },
}

*Betacoronavirus
COVID-19
*Coronavirus Infections
Desensitization, Immunologic
Humans
*Pandemics
*Pneumonia, Viral
SARS-CoV-2

@article {pmid32754159,
year = {2020},
author = {Bhaskar, S and Sinha, A and Banach, M and Mittoo, S and Weissert, R and Kass, JS and Rajagopal, S and Pai, AR and Kutty, S},
title = {Cytokine Storm in COVID-19-Immunopathological Mechanisms, Clinical Considerations, and Therapeutic Approaches: The REPROGRAM Consortium Position Paper.},
journal = {Frontiers in immunology},
volume = {11},
number = {},
pages = {1648},
pmid = {32754159},
issn = {1664-3224},
support = {001/WHO_/World Health Organization/International ; },
mesh = {Adrenal Cortex Hormones/therapeutic use ; Angiotensin-Converting Enzyme 2 ; Anti-Inflammatory Agents, Non-Steroidal/therapeutic use ; Betacoronavirus/*immunology ; CD4-CD8 Ratio ; CD4-Positive T-Lymphocytes/immunology ; CD8-Positive T-Lymphocytes/immunology ; COVID-19 ; Clinical Decision-Making/methods ; Coronavirus Infections/blood/*drug therapy/*immunology/mortality ; Critical Care/*methods ; Critical Illness ; Cytokines/*blood ; Endothelial Cells/metabolism ; Female ; Humans ; Immunocompromised Host ; Interleukin-6/antagonists & inhibitors ; Janus Kinase Inhibitors/therapeutic use ; Male ; Pandemics ; Peptidyl-Dipeptidase A/metabolism ; Pneumonia, Viral/blood/*drug therapy/*immunology/mortality ; SARS-CoV-2 ; Sex Factors ; Thrombosis ; },
abstract = {Cytokine storm is an acute hyperinflammatory response that may be responsible for critical illness in many conditions including viral infections, cancer, sepsis, and multi-organ failure. The phenomenon has been implicated in critically ill patients infected with SARS-CoV-2, the novel coronavirus implicated in COVID-19. Critically ill COVID-19 patients experiencing cytokine storm are believed to have a worse prognosis and increased fatality rate. In SARS-CoV-2 infected patients, cytokine storm appears important to the pathogenesis of several severe manifestations of COVID-19: acute respiratory distress syndrome, thromboembolic diseases such as acute ischemic strokes caused by large vessel occlusion and myocardial infarction, encephalitis, acute kidney injury, and vasculitis (Kawasaki-like syndrome in children and renal vasculitis in adult). Understanding the pathogenesis of cytokine storm will help unravel not only risk factors for the condition but also therapeutic strategies to modulate the immune response and deliver improved outcomes in COVID-19 patients at high risk for severe disease. In this article, we present an overview of the cytokine storm and its implications in COVID-19 settings and identify potential pathways or biomarkers that could be targeted for therapy. Leveraging expert opinion, emerging evidence, and a case-based approach, this position paper provides critical insights on cytokine storm from both a prognostic and therapeutic standpoint.},
}

Adrenal Cortex Hormones/therapeutic use
Angiotensin-Converting Enzyme 2
Anti-Inflammatory Agents, Non-Steroidal/therapeutic use
Betacoronavirus/*immunology
CD4-CD8 Ratio
CD4-Positive T-Lymphocytes/immunology
CD8-Positive T-Lymphocytes/immunology
COVID-19
Clinical Decision-Making/methods
Coronavirus Infections/blood/*drug therapy/*immunology/mortality
Critical Care/*methods
Critical Illness
Cytokines/*blood
Endothelial Cells/metabolism
Female
Humans
Immunocompromised Host
Interleukin-6/antagonists & inhibitors
Janus Kinase Inhibitors/therapeutic use
Male
Pandemics
Peptidyl-Dipeptidase A/metabolism
Pneumonia, Viral/blood/*drug therapy/*immunology/mortality
SARS-CoV-2
Sex Factors
Thrombosis

@article {pmid32748068,
year = {2020},
author = {Stolbach, A and Mazer-Amirshahi, M and Schwarz, ES and Juurlink, D and Wiegand, TJ and Nelson, LS},
title = {ACMT Position Statement: Caring for Patients with Opioid Use Disorder during Coronavirus Disease Pandemic.},
journal = {Journal of medical toxicology : official journal of the American College of Medical Toxicology},
volume = {16},
number = {4},
pages = {484-486},
pmid = {32748068},
issn = {1937-6995},
mesh = {*Betacoronavirus ; COVID-19 ; Coronavirus Infections/*epidemiology ; Health Services Accessibility ; Humans ; Opioid-Related Disorders/*therapy ; Pandemics ; Pneumonia, Viral/*epidemiology ; SARS-CoV-2 ; Toxicology ; },
}

*Betacoronavirus
COVID-19
Coronavirus Infections/*epidemiology
Health Services Accessibility
Humans
Opioid-Related Disorders/*therapy
Pandemics
Pneumonia, Viral/*epidemiology
SARS-CoV-2
Toxicology

@article {pmid32740024,
year = {2020},
author = {Maculotti, D and Spena, PR and Villa, G},
title = {POSITION STATEMENT ON CARE OF OSTOMY PATIENTS DURING COVID-19 PANDEMIC.},
journal = {Gastroenterology nursing : the official journal of the Society of Gastroenterology Nurses and Associates},
volume = {43},
number = {4},
pages = {324-326},
doi = {10.1097/SGA.0000000000000539},
pmid = {32740024},
issn = {1538-9766},
mesh = {Ambulatory Care ; *Betacoronavirus ; COVID-19 ; Coronavirus Infections/*epidemiology/prevention & control/transmission ; Hospitalization ; Humans ; Infection Control/*organization & administration ; *Ostomy ; Pandemics/prevention & control ; Patient Selection ; Pneumonia, Viral/*epidemiology/prevention & control/transmission ; SARS-CoV-2 ; },
}

Ambulatory Care
*Betacoronavirus
COVID-19
Coronavirus Infections/*epidemiology/prevention & control/transmission
Hospitalization
Humans
Infection Control/*organization & administration
*Ostomy
Pandemics/prevention & control
Patient Selection
Pneumonia, Viral/*epidemiology/prevention & control/transmission
SARS-CoV-2

@article {pmid32732509,
year = {2020},
author = {Moore, TA},
title = {Overview of the Care of Mothers and Newborns With COVID-19; Joint Position Statement.},
journal = {Advances in neonatal care : official journal of the National Association of Neonatal Nurses},
volume = {20},
number = {4},
pages = {268},
pmid = {32732509},
issn = {1536-0911},
mesh = {American Nurses' Association ; Betacoronavirus ; COVID-19 ; *Coronavirus Infections/epidemiology/prevention & control ; *Evidence-Based Nursing/methods/trends ; Female ; Humans ; Infant, Newborn ; Infection Control/organization & administration ; *Neonatal Nursing/organization & administration/standards ; Organizational Innovation ; *Pandemics/prevention & control ; *Pneumonia, Viral/epidemiology/prevention & control ; *Postnatal Care/methods/organization & administration/trends ; SARS-CoV-2 ; United States ; },
}

American Nurses' Association
Betacoronavirus
COVID-19
*Coronavirus Infections/epidemiology/prevention & control
*Evidence-Based Nursing/methods/trends
Female
Humans
Infant, Newborn
Infection Control/organization & administration
*Neonatal Nursing/organization & administration/standards
Organizational Innovation
*Pandemics/prevention & control
*Pneumonia, Viral/epidemiology/prevention & control
*Postnatal Care/methods/organization & administration/trends
SARS-CoV-2
United States

@article {pmid32719884,
year = {2020},
author = {Gutenbrunner, C and Stokes, EK and Dreinhöfer, K and Monsbakken, J and Clarke, S and Côté, P and Urseau, I and Constantine, D and Tardif, C and Balakrishna, V and Nugraha, B},
title = {Why Rehabilitation must have priority during and after the COVID-19-pandemic: A position statement of the Global Rehabilitation Alliance.},
journal = {Journal of rehabilitation medicine},
volume = {52},
number = {7},
pages = {jrm00081},
doi = {10.2340/16501977-2713},
pmid = {32719884},
issn = {1651-2081},
mesh = {*Betacoronavirus ; COVID-19 ; Coronavirus Infections/prevention & control/*rehabilitation ; Global Health ; Health Services Accessibility/standards ; Humans ; Infection Control/standards ; Pandemics/prevention & control ; Pneumonia, Viral/prevention & control/*rehabilitation ; SARS-CoV-2 ; },
abstract = {COVID-19 has become a pandemic with strong influence on health systems. In many cases it leads to a disruption of rehabilitation service provision. On the other hand, rehabilitation must be an integral part of COVID-19 management. Rehabilitation for COVID-19 should start from acute and early post-acute care and needs to be continued in the post-acute and long-term rehabilitation phase. Of course, it should follow specific safety protocol. Additionally, rehabilitation must be kept available for all other people who are in need. From the perspective of health system, the Global Rehabilitation Alliance urges decision makers to ensure that rehabilitation services will be available for all patients with COVID-19 in the acute, post-acute and long-term phase. Additionally, it must be ensured that all other persons with rehabilitation need have access to rehabilitation services. Rehabilitation services must be equipped with personal protection equipment and follow strict hygiene measures. In particular, rehabilitation must be accessible for vulnerable populations. For that reason, rehabilitation must be kept a health priority during the COVID-19 pandemic and given adequate financial resources. Last but not least, scientific studies should be performed to clarify the impact of the pandemic on rehabilitation services as well as on the needs for rehabilitation of COVID-19 patients.},
}

*Betacoronavirus
COVID-19
Coronavirus Infections/prevention & control/*rehabilitation
Global Health
Health Services Accessibility/standards
Humans
Infection Control/standards
Pandemics/prevention & control
Pneumonia, Viral/prevention & control/*rehabilitation
SARS-CoV-2

@article {pmid32694078,
year = {2020},
author = {Vivas, D and Roldán, V and Esteve-Pastor, MA and Roldán, I and Tello-Montoliu, A and Ruiz-Nodar, JM and Cosín-Sales, J and Gámez, JM and Consuegra, L and Ferreiro, JL and Marín, F and , },
title = {Recommendations on antithrombotic treatment during the COVID-19 pandemic. Position statement of the Working Group on Cardiovascular Thrombosis of the Spanish Society of Cardiology.},
journal = {Revista espanola de cardiologia (English ed.)},
volume = {73},
number = {9},
pages = {749-757},
pmid = {32694078},
issn = {1885-5857},
mesh = {*Betacoronavirus ; COVID-19 ; Cardiology ; Coronavirus Infections/*drug therapy ; Fibrinolytic Agents/*therapeutic use ; Humans ; Pandemics ; Patient Selection ; Pneumonia, Viral/*drug therapy ; SARS-CoV-2 ; Societies, Medical ; Spain ; COVID-19 Drug Treatment ; },
abstract = {The new coronavirus SARS-CoV-2, which gives rise to the highly contagious COVID-19 disease, has caused a pandemic that is overwhelming health care systems worldwide. Affected patients have been reported to have a heightened inflammatory state that increases their thrombotic risk. However, there is very scarce information on the management of thrombotic risk, coagulation disorders, and anticoagulant therapy. In addition, the situation has also greatly influenced usual care in patients not infected with COVID-19. This article by the Working Group on Cardiovascular Thrombosis of the Spanish Society of Cardiology aims to summarize the available information and to provide a practical approach to the management of antithrombotic therapy.},
}

*Betacoronavirus
COVID-19
Cardiology
Coronavirus Infections/*drug therapy
Fibrinolytic Agents/*therapeutic use
Humans
Pandemics
Patient Selection
Pneumonia, Viral/*drug therapy
SARS-CoV-2
Societies, Medical
Spain
COVID-19 Drug Treatment

@article {pmid32675009,
year = {2020},
author = {Torlone, E and Festa, C and Formoso, G and Scavini, M and Sculli, MA and Succurro, E and Sciacca, L and Di Bartolo, P and Purrello, F and Lapolla, A},
title = {Italian recommendations for the diagnosis of gestational diabetes during COVID-19 pandemic: Position statement of the Italian Association of Clinical Diabetologists (AMD) and the Italian Diabetes Society (SID), diabetes, and pregnancy study group.},
journal = {Nutrition, metabolism, and cardiovascular diseases : NMCD},
volume = {30},
number = {9},
pages = {1418-1422},
pmid = {32675009},
issn = {1590-3729},
mesh = {*Betacoronavirus ; Blood Glucose/analysis ; COVID-19 ; Coronavirus Infections/*epidemiology ; Diabetes, Gestational/*diagnosis ; Female ; Glucose Tolerance Test ; Humans ; Italy ; Pandemics ; Pneumonia, Viral/*epidemiology ; Pregnancy ; SARS-CoV-2 ; },
abstract = {AIM: In response to the COVID-19 pandemic, there is a need for substantial changes in the procedures for accessing healthcare services. Even in the current pandemic, we should not reduce our attention towards the diagnosis and treatment of GDM. The purpose of this document is to provide a temporary guide for GDM screening, replacing the current guidelines when it is not possible to implement standard GDM screening because of an unfavorable risk/benefit ratio for pregnant women or when usual laboratory facilities are not available.

DATA SYNTHESIS: At the first visit during pregnancy, we must exclude the presence of "Overt diabetes" in all women. The criteria for the diagnosis of overt diabetes are either fasting plasma glucose ≥126 mg/dL, or random plasma glucose ≥200 mg/dL, or glycated hemoglobin ≥6.5%. When the screening procedure (OGTT) cannot be safely performed, the diagnosis of GDM is acceptable if fasting plasma glucose is ≥ 92 mg/dL. In order to consider the impaired fasting glucose as an acceptable surrogate for the diagnosis of GDM, the fasting glucose measurement should be performed within the recommended time windows for the risk level (high or medium risk).

CONCLUSIONS: The changes to the screening procedure for GDM reported below are specifically produced in response to the health emergency of the COVID-19 pandemic. Therefore, these recommended changes should cease to be in effect and should be replaced by current national guidelines when the healthcare authorities declare the end of this emergency.},
}

*Betacoronavirus
Blood Glucose/analysis
COVID-19
Coronavirus Infections/*epidemiology
Diabetes, Gestational/*diagnosis
Female
Glucose Tolerance Test
Humans
Italy
Pandemics
Pneumonia, Viral/*epidemiology
Pregnancy
SARS-CoV-2

@article {pmid32674177,
year = {2020},
author = {Kolditz, M and Dellweg, D and Geerdes-Fenge, H and Lepper, PM and Schaberg, T and Ewig, S and Pfeifer, M and Bauer, T},
title = {[Treatment with Dexamethasone in Patients with COVID-19 - A Position Paper of the German Respiratory Society (DGP)].},
journal = {Pneumologie (Stuttgart, Germany)},
volume = {74},
number = {8},
pages = {493-495},
pmid = {32674177},
issn = {1438-8790},
mesh = {Anti-Inflammatory Agents/*therapeutic use ; Betacoronavirus ; COVID-19 ; Coronavirus/*isolation & purification ; Coronavirus Infections/diagnosis/*drug therapy ; Dexamethasone/*therapeutic use ; Germany ; Humans ; *Pandemics ; Pneumonia, Viral/diagnosis/*drug therapy ; *Practice Guidelines as Topic ; SARS-CoV-2 ; Societies, Medical ; Treatment Outcome ; COVID-19 Drug Treatment ; },
}

Anti-Inflammatory Agents/*therapeutic use
Betacoronavirus
COVID-19
Coronavirus/*isolation & purification
Coronavirus Infections/diagnosis/*drug therapy
Dexamethasone/*therapeutic use
Germany
Humans
*Pandemics
Pneumonia, Viral/diagnosis/*drug therapy
*Practice Guidelines as Topic
SARS-CoV-2
Societies, Medical
Treatment Outcome
COVID-19 Drug Treatment

@article {pmid32643767,
year = {2020},
author = {Gralnek, IM and Hassan, C and Beilenhoff, U and Antonelli, G and Ebigbo, A and Pellisé, M and Arvanitakis, M and Bhandari, P and Bisschops, R and Van Hooft, JE and Kaminski, MF and Triantafyllou, K and Webster, G and Voiosu, AM and Pohl, H and Dunkley, I and Fehrke, B and Gazic, M and Gjergek, T and Maasen, S and Waagenes, W and de Pater, M and Ponchon, T and Siersema, PD and Messmann, H and Dinis-Ribeiro, M},
title = {ESGE and ESGENA Position Statement on gastrointestinal endoscopy and COVID-19: An update on guidance during the post-lockdown phase and selected results from a membership survey.},
journal = {Endoscopy},
volume = {52},
number = {10},
pages = {891-898},
pmid = {32643767},
issn = {1438-8812},
mesh = {Humans ; Betacoronavirus ; *Coronavirus Infections ; COVID-19 ; *Endoscopy, Gastrointestinal ; *Pandemics ; *Pneumonia, Viral ; SARS-CoV-2 ; Surveys and Questionnaires ; },
}

Humans
Betacoronavirus
*Coronavirus Infections
COVID-19
*Endoscopy, Gastrointestinal
*Pandemics
*Pneumonia, Viral
SARS-CoV-2
Surveys and Questionnaires

@article {pmid32638902,
year = {2020},
author = {Guimarães, HP and Timerman, S and Rodrigues, RDR and Corrêa, TD and Schubert, DUC and Freitas, AP and Rea Neto, Á and Polastri, TF and Vane, MF and Couto, TB and Brandão, ACA and Giannetti, NS and Timerman, T and Hajjar, LA and Bacal, F and Lopes, MACQ},
title = {Position Statement: Cardiopulmonary Resuscitation of Patients with Confirmed or Suspected COVID-19 - 2020.},
journal = {Arquivos brasileiros de cardiologia},
volume = {114},
number = {6},
pages = {1078-1087},
pmid = {32638902},
issn = {1678-4170},
mesh = {Advisory Committees ; Betacoronavirus ; Brazil/epidemiology ; COVID-19 ; Cardiopulmonary Resuscitation/methods/*standards ; *Coronavirus ; Coronavirus Infections/diagnosis/epidemiology/*therapy ; Humans ; *Pandemics ; Pneumonia, Viral/diagnosis/epidemiology/*therapy ; *Practice Guidelines as Topic ; SARS-CoV-2 ; Societies, Medical ; United States ; },
abstract = {Care for patients with cardiac arrest in the context of the coronavirus disease 2019 (COVID-19) pandemic has several unique aspects that warrant particular attention. This joint position statement by the Brazilian Association of Emergency Medicine (ABRAMEDE), Brazilian Society of Cardiology (SBC), Brazilian Association of Intensive Care Medicine (AMIB), and Brazilian Society of Anesthesiology (SBA), all official societies representing the corresponding medical specialties affiliated with the Brazilian Medical Association (AMB), provides recommendations to guide health care workers in the current context of limited robust evidence, aiming to maximize the protection of staff and patients alike. It is essential that full aerosol precautions, which include wearing appropriate personal protective equipment, be followed during resuscitation. It is also imperative that potential causes of cardiac arrest of particular interest in this patient population, especially hypoxia, cardiac arrhythmias associated with QT prolongation, and myocarditis, be considered and addressed. An advanced invasive airway device should be placed early. Use of HEPA filters at the bag-valve interface is mandatory. Management of cardiac arrest occurring during mechanical ventilation or during prone positioning demands particular ventilator settings and rescuer positioning for chest compressions which deviate from standard cardiopulmonary resuscitation techniques. Apart from these logistical issues, care should otherwise follow national and international protocols and guidelines, namely the 2015 International Liaison Committee on Resuscitation (ILCOR) and 2019 American Heart Association (AHA) guidelines and the 2019 Update to the Brazilian Society of Cardiology Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Guideline.},
}

Advisory Committees
Betacoronavirus
Brazil/epidemiology
COVID-19
Cardiopulmonary Resuscitation/methods/*standards
*Coronavirus
Coronavirus Infections/diagnosis/epidemiology/*therapy
Humans
*Pandemics
Pneumonia, Viral/diagnosis/epidemiology/*therapy
*Practice Guidelines as Topic
SARS-CoV-2
Societies, Medical
United States

@article {pmid32623686,
year = {2020},
author = {Stier, C and Lopez-Nava, G and Neto, MG and Thompson, CC and Campos, J and Khoursheed, M and Lakdawala, M and Ramos, A and Abu Dayyeh, BK},
title = {IFSO Endoscopy Committee Position Statement on the Practice of Bariatric Endoscopy During the COVID-19 Pandemic.},
journal = {Obesity surgery},
volume = {30},
number = {11},
pages = {4179-4186},
pmid = {32623686},
issn = {1708-0428},
mesh = {*Bariatrics ; *Betacoronavirus ; COVID-19 ; Coronavirus Infections/epidemiology/*prevention & control/transmission ; *Endoscopy ; Humans ; Infection Control/*organization & administration ; Obesity, Morbid/*surgery ; Pandemics/*prevention & control ; Patient Selection ; Pneumonia, Viral/epidemiology/*prevention & control/transmission ; Practice Guidelines as Topic ; SARS-CoV-2 ; },
abstract = {COVID-19 (Coronavirus disease 2019) caused by SARS-CoV-2 has become a global pandemic. Obesity is a risk factor for severe disease, and the practice of endoscopy poses special challenges and risks of SARS-CoV-2 transmission to patients and providers given the evolving role of the gastrointestinal tract in viral transmission and aerosol generation during endoscopic procedures. It is therefore necessary to distinguish between urgent interventions that cannot be postponed despite the risks during the pandemic and, in contrast, purely elective interventions that could be deferred in order to minimize transmission risks during a time of infection surge and limited access. Semi-urgent bariatric procedures have an intermediate position. Since the chronological course of the pandemic is still unpredictable, these interventions were defined according to whether or not they should be performed within a nominal 8-week period. In this position statement, the IFSO Endoscopy Committee offers guidance on navigating bariatric endoscopic procedures in patients with obesity during the COVID-19 pandemic, in the hope of mitigating the risk of SARS-CoV-2 transmission to vulnerable patients and healthcare workers. These recommendations may evolve as the pandemic progresses.},
}

*Bariatrics
*Betacoronavirus
COVID-19
Coronavirus Infections/epidemiology/*prevention & control/transmission
*Endoscopy
Humans
Infection Control/*organization & administration
Obesity, Morbid/*surgery
Pandemics/*prevention & control
Patient Selection
Pneumonia, Viral/epidemiology/*prevention & control/transmission
Practice Guidelines as Topic
SARS-CoV-2

@article {pmid32620315,
year = {2020},
author = {Miranda-Zazueta, G and González-Regueiro, JA and García-Juárez, I and Moctezuma-Velázquez, C and López-Díaz, FJ and Pérez-González, B and Uscanga-Domínguez, LF and Peláez-Luna, M},
title = {Pharmacologic management of patients with hepatic and pancreatic diseases that involve immunosuppressive therapies. Position statement within the framework of the SARS-CoV-2 (COVID-19) pandemic.},
journal = {Revista de gastroenterologia de Mexico (English)},
volume = {85},
number = {3},
pages = {312-320},
pmid = {32620315},
issn = {2255-534X},
mesh = {COVID-19 ; Coronavirus Infections/*complications ; Humans ; Immunosuppressive Agents/*adverse effects/*therapeutic use ; Liver Diseases/complications/*drug therapy ; Liver Transplantation ; Pancreas Transplantation ; Pancreatic Diseases/complications/*drug therapy ; *Pandemics ; Pneumonia, Viral/*complications ; },
abstract = {The coronavirus disease 2019 (COVID-19) is caused by the severe acute respiratory syndrome coronavirus2 (SARS-CoV-2) virus. COVID-19 affected more than 6million persons worldwide in fewer than 4 months, after the report of the first cases in China in December 2019. The relation of the disease caused by SARS-Cov-2 to immunosuppressive treatment used in different gastrointestinal disorders is uncertain, resulting in debate with regard to suspending immunosuppressive therapy to improve infection outcome. Said suspension implies the inherent risk for graft rejection or autoimmune disease exacerbation that can potentially worsen the course of the infection. Based on the presently available evidence, a treatment stance has been established for patients with gastrointestinal diseases that require immunosuppressive therapy.},
}

COVID-19
Coronavirus Infections/*complications
Humans
Immunosuppressive Agents/*adverse effects/*therapeutic use
Liver Diseases/complications/*drug therapy
Liver Transplantation
Pancreas Transplantation
Pancreatic Diseases/complications/*drug therapy
*Pandemics
Pneumonia, Viral/*complications

@article {pmid32617893,
year = {2020},
author = {Farmer, BM and Cole, JB and Olives, TD and Farrell, NM and Rao, R and Nelson, LS and Mazer-Amirshahi, M and Stolbach, AI},
title = {ACMT Position Statement: Medication Administration and Safety During the Response to COVID-19 Pandemic.},
journal = {Journal of medical toxicology : official journal of the American College of Medical Toxicology},
volume = {16},
number = {4},
pages = {481-483},
pmid = {32617893},
issn = {1937-6995},
mesh = {*Betacoronavirus ; COVID-19 ; Coronavirus Infections/drug therapy/*epidemiology/prevention & control ; Health Personnel/education ; Humans ; Pandemics/prevention & control ; Personal Protective Equipment ; Pneumonia, Viral/drug therapy/*epidemiology/prevention & control ; SARS-CoV-2 ; Toxicology ; },
}

*Betacoronavirus
COVID-19
Coronavirus Infections/drug therapy/*epidemiology/prevention & control
Health Personnel/education
Humans
Pandemics/prevention & control
Personal Protective Equipment
Pneumonia, Viral/drug therapy/*epidemiology/prevention & control
SARS-CoV-2
Toxicology

@article {pmid32613918,
year = {2020},
author = {Geneid, A and Nawka, T and Schindler, A and Oguz, H and Chrobok, V and Calcinoni, O and Am Zehnhoff-Dinnesen, A and Neumann, K and Farahat, M and Abou-Elsaad, T and Moerman, M and Chavez, E and Fishman, J and Yazaki, R and Arnold, B and Frajkova, Z and Graf, S and Pflug, C and Drsata, J and Desuter, G and Samuelsson, C and Tedla, M and Costello, D and Sjögren, E and Hess, M and Kinnari, T and Rubin, J},
title = {Union of the European Phoniatricians' position statement on the exit strategy of phoniatric and laryngological services: staying safe and getting back to normal after the peak of coronavirus disease 2019 (issued on 25th May 2020).},
journal = {The Journal of laryngology and otology},
volume = {134},
number = {8},
pages = {661-664},
pmid = {32613918},
issn = {1748-5460},
mesh = {Audiology/*methods/standards ; Betacoronavirus/*isolation & purification ; COVID-19 ; Child ; Child, Preschool ; Coronavirus Infections/epidemiology/*prevention & control/virology ; Deglutition Disorders/diagnosis/surgery/virology ; Europe/epidemiology ; Humans ; Mandatory Testing/standards ; Otolaryngology/*methods/standards ; Pandemics/*prevention & control ; Pediatrics/standards ; Personal Protective Equipment/standards/supply & distribution ; Pneumonia, Viral/epidemiology/*prevention & control/virology ; Practice Guidelines as Topic ; SARS-CoV-2 ; Societies, Medical/organization & administration ; Voice Disorders/diagnosis/surgery/virology ; },
abstract = {BACKGROUND: The following position statement from the Union of the European Phoniatricians, updated on 25th May 2020 (superseding the previous statement issued on 21st April 2020), contains a series of recommendations for phoniatricians and ENT surgeons who provide and/or run voice, swallowing, speech and language, or paediatric audiology services.

OBJECTIVES: This material specifically aims to inform clinical practices in countries where clinics and operating theatres are reopening for elective work. It endeavours to present a current European view in relation to common procedures, many of which fall under the aegis of aerosol generating procedures.

CONCLUSION: As evidence continues to build, some of the recommended practices will undoubtedly evolve, but it is hoped that the updated position statement will offer clinicians precepts on safe clinical practice.},
}

Audiology/*methods/standards
Betacoronavirus/*isolation & purification
COVID-19
Child
Child, Preschool
Coronavirus Infections/epidemiology/*prevention & control/virology
Deglutition Disorders/diagnosis/surgery/virology
Europe/epidemiology
Humans
Mandatory Testing/standards
Otolaryngology/*methods/standards
Pandemics/*prevention & control
Pediatrics/standards
Personal Protective Equipment/standards/supply & distribution
Pneumonia, Viral/epidemiology/*prevention & control/virology
Practice Guidelines as Topic
SARS-CoV-2
Societies, Medical/organization & administration
Voice Disorders/diagnosis/surgery/virology

@article {pmid32601022,
year = {2020},
author = {Parsonage, WA and Cullen, L and Brieger, D and Hillis, GS and Nasis, A and Dwyer, N and Wahi, S and Lo, S and Than, M and Kerr, A and Devlin, G and Chew, DK},
title = {CSANZ Position Statement on the Evaluation of Patients Presenting With Suspected Acute Coronary Syndromes During the COVID-19 Pandemic.},
journal = {Heart, lung & circulation},
volume = {29},
number = {7},
pages = {e105-e110},
pmid = {32601022},
issn = {1444-2892},
mesh = {*Acute Coronary Syndrome/diagnosis/epidemiology/therapy ; Australia/epidemiology ; Betacoronavirus ; COVID-19 ; *Cardiology/methods/organization & administration/trends ; *Communicable Disease Control/methods/organization & administration ; Consensus ; *Coronavirus Infections/epidemiology/prevention & control ; Humans ; Infection Control/*organization & administration ; New Zealand/epidemiology ; *Pandemics/prevention & control ; Patient Care Management/*methods ; *Pneumonia, Viral/epidemiology/prevention & control ; SARS-CoV-2 ; Societies, Medical ; },
abstract = {A pandemic of Coronavirus-19 disease was declared by the World Health Organization on March 11, 2020. The pandemic is expected to place unprecedented demand on health service delivery. This position statement has been developed by the Cardiac Society of Australia and New Zealand to assist clinicians to continue to deliver rapid and safe evaluation of patients presenting with suspected acute cardiac syndrome at this time. The position statement complements, and should be read in conjunction with, the National Heart Foundation of Australia & Cardiac Society of Australia and New Zealand: Australian Clinical Guidelines for the Management of Acute Coronary Syndromes 2016: Section 2 'Assessment of Possible Cardiac Chest Pain'.},
}

*Acute Coronary Syndrome/diagnosis/epidemiology/therapy
Australia/epidemiology
Betacoronavirus
COVID-19
*Cardiology/methods/organization & administration/trends
*Communicable Disease Control/methods/organization & administration
Consensus
*Coronavirus Infections/epidemiology/prevention & control
Humans
Infection Control/*organization & administration
New Zealand/epidemiology
*Pandemics/prevention & control
Patient Care Management/*methods
*Pneumonia, Viral/epidemiology/prevention & control
SARS-CoV-2
Societies, Medical

@article {pmid32574446,
year = {2020},
author = {},
title = {UHMS Position Statement: Hyperbaric Oxygen (HBO2) for COVID-19 Patients.},
journal = {Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc},
volume = {47},
number = {2},
pages = {297-298},
pmid = {32574446},
issn = {1066-2936},
mesh = {*Betacoronavirus ; COVID-19 ; Clinical Trials as Topic ; Coronavirus Infections/complications/*therapy ; Humans ; *Hyperbaric Oxygenation/adverse effects/methods ; Hypoxia/etiology/therapy ; Pandemics ; Pneumonia/etiology/therapy ; Pneumonia, Viral/complications/*therapy ; SARS-CoV-2 ; Societies, Medical ; },
abstract = {There have been numerous recent inquiries regarding use of hyperbaric oxygen (HBO2) for patients with COVID-19. Questions have been raised pertinent to two possible mechanisms for HBO2 in this clinical context. The UHMS Hyperbaric Oxygen Therapy Committee, UHMS Executive Committee, with collaborative input from multiple senior UHMS members and researchers have drafted this position statement.},
}

*Betacoronavirus
COVID-19
Clinical Trials as Topic
Coronavirus Infections/complications/*therapy
Humans
*Hyperbaric Oxygenation/adverse effects/methods
Hypoxia/etiology/therapy
Pandemics
Pneumonia/etiology/therapy
Pneumonia, Viral/complications/*therapy
SARS-CoV-2
Societies, Medical

@article {pmid32548994,
year = {2020},
author = {Mureddu, GF and Ambrosetti, M and Venturini, E and La Rovere, MT and Mazza, A and Pedretti, R and Sarullo, F and Fattirolli, F and Faggiano, P and Giallauria, F and Vigorito, C and Angelino, E and Brazzo, S and Ruzzolini, M},
title = {Cardiac rehabilitation activities during the COVID-19 pandemic in Italy. Position Paper of the AICPR (Italian Association of Clinical Cardiology, Prevention and Rehabilitation).},
journal = {Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace},
volume = {90},
number = {2},
pages = {},
doi = {10.4081/monaldi.2020.1439},
pmid = {32548994},
issn = {2532-5264},
mesh = {Acute Coronary Syndrome/rehabilitation ; COVID-19 ; Cardiac Rehabilitation/psychology/*standards ; Cardiotonic Agents/adverse effects/therapeutic use ; Coronavirus Infections/*epidemiology ; Exercise ; Female ; Heart Failure/rehabilitation ; Humans ; Italy/epidemiology ; Male ; Nutrition Therapy ; Pandemics ; Pneumonia, Viral/*epidemiology ; Thromboembolism/rehabilitation ; },
abstract = {The COVID-19 outbreak is having a significant impact on both cardiac rehabilitation (CR) inpatient and outpatient healthcare organization. The variety of clinical and care scenarios we are observing in Italy depends on the region, the organization of local services and the hospital involved. Some hospital wards have been closed to make room to dedicated beds or to quarantine the exposed health personnel. In other cases, CR units have been converted or transformed into COVID-19 units. The present document aims at defining the state of the art of CR during COVID-19 pandemic, through the description of the clinical and management scenarios frequently observed during this period and the exploration of the future frontiers in the management of cardiac rehabilitation programs after the COVID-19 outbreak.},
}

Acute Coronary Syndrome/rehabilitation
COVID-19
Cardiac Rehabilitation/psychology/*standards
Cardiotonic Agents/adverse effects/therapeutic use
Coronavirus Infections/*epidemiology
Exercise
Female
Heart Failure/rehabilitation
Humans
Italy/epidemiology
Male
Nutrition Therapy
Pandemics
Pneumonia, Viral/*epidemiology
Thromboembolism/rehabilitation

@article {pmid32541561,
year = {2020},
author = {Zidan, A and Alabbad, S and Ali, T and Nizami, I and Haberal, M and Tokat, Y and Kamel, R and Said, H and Abdelaal, A and Elsharkawy, M and El Fouly, A and Sayed, H and Al-Mousawi, M and AlGhonaim, M and Broering, D},
title = {Position Statement of Transplant Activity in the Middle East in Era of COVID-19 Pandemic.},
journal = {Transplantation},
volume = {104},
number = {11},
pages = {2205-2207},
pmid = {32541561},
issn = {1534-6080},
mesh = {Betacoronavirus ; COVID-19 ; Coronavirus Infections/*epidemiology ; Delivery of Health Care/*standards ; Humans ; Middle East ; Organ Transplantation/statistics & numerical data/*trends ; Pandemics ; Pneumonia, Viral/*epidemiology ; SARS-CoV-2 ; },
}

Betacoronavirus
COVID-19
Coronavirus Infections/*epidemiology
Delivery of Health Care/*standards
Humans
Middle East
Organ Transplantation/statistics & numerical data/*trends
Pandemics
Pneumonia, Viral/*epidemiology
SARS-CoV-2

@article {pmid32537929,
year = {2020},
author = {Hamad, N and Gottlieb, D and Ritchie, D and Kennedy, G and Watson, AM and Greenwood, M and Doocey, R and Perera, T and Spencer, A and Wong, E and O'Brien, T and Shaw, P and Conyers, R and Cole, T and Milliken, S and Bardy, P and Larsen, S and Lai, H and Butler, A and Fraser, C and Bajel, A and Butler, J and Kerridge, I and Purtill, D},
title = {Bone Marrow Transplant Society of Australia and New Zealand COVID-19 consensus position statement.},
journal = {Internal medicine journal},
volume = {50},
number = {6},
pages = {774-775},
doi = {10.1111/imj.14867},
pmid = {32537929},
issn = {1445-5994},
mesh = {Australia ; COVID-19 ; COVID-19 Testing ; Clinical Laboratory Techniques/*methods/statistics & numerical data ; Comorbidity ; *Consensus ; Coronavirus Infections/*diagnosis/physiopathology/therapy/virology ; Cryopreservation ; Hematopoietic Stem Cell Transplantation/*methods ; Humans ; Leukemia/physiopathology/*therapy ; New Zealand ; Pandemics ; Pneumonia, Viral/*diagnosis/physiopathology/therapy/virology ; Practice Guidelines as Topic ; Triage ; },
}

Australia
COVID-19
COVID-19 Testing
Clinical Laboratory Techniques/*methods/statistics & numerical data
Comorbidity
*Consensus
Coronavirus Infections/*diagnosis/physiopathology/therapy/virology
Cryopreservation
Hematopoietic Stem Cell Transplantation/*methods
Humans
Leukemia/physiopathology/*therapy
New Zealand
Pandemics
Pneumonia, Viral/*diagnosis/physiopathology/therapy/virology
Practice Guidelines as Topic
Triage

@article {pmid32531110,
year = {2021},
author = {Pfaar, O and Klimek, L and Jutel, M and Akdis, CA and Bousquet, J and Breiteneder, H and Chinthrajah, S and Diamant, Z and Eiwegger, T and Fokkens, WJ and Fritsch, HW and Nadeau, KC and O'Hehir, RE and O'Mahony, L and Rief, W and Sampath, V and Schedlowski, M and Torres, MJ and Traidl-Hoffmann, C and Wang, Y and Zhang, L and Bonini, M and Brehler, R and Brough, HA and Chivato, T and Del Giacco, SR and Dramburg, S and Gawlik, R and Gelincik, A and Hoffmann-Sommergruber, K and Hox, V and Knol, EF and Lauerma, A and Matricardi, PM and Mortz, CG and Ollert, M and Palomares, O and Riggioni, C and Schwarze, J and Skypala, I and Untersmayr, E and Walusiak-Skorupa, J and Ansotegui, IJ and Bachert, C and Bedbrook, A and Bosnic-Anticevich, S and Brussino, L and Canonica, GW and Cardona, V and Carreiro-Martins, P and Cruz, AA and Czarlewski, W and Fonseca, JA and Gotua, M and Haahtela, T and Ivancevich, JC and Kuna, P and Kvedariene, V and Larenas-Linnemann, DE and Abdul Latiff, AH and Mäkelä, M and Morais-Almeida, M and Mullol, J and Naclerio, R and Ohta, K and Okamoto, Y and Onorato, GL and Papadopoulos, NG and Patella, V and Regateiro, FS and Samoliński, B and Suppli Ulrik, C and Toppila-Salmi, S and Valiulis, A and Ventura, MT and Yorgancioglu, A and Zuberbier, T and Agache, I},
title = {COVID-19 pandemic: Practical considerations on the organization of an allergy clinic-An EAACI/ARIA Position Paper.},
journal = {Allergy},
volume = {76},
number = {3},
pages = {648-676},
pmid = {32531110},
issn = {1398-9995},
mesh = {Allergists ; COVID-19/*epidemiology/prevention & control ; Health Personnel ; Humans ; Hypersensitivity/diagnosis/*therapy ; Information Technology ; Patient Care Team ; *SARS-CoV-2 ; Triage ; },
abstract = {BACKGROUND: The coronavirus disease 2019 (COVID-19) has evolved into a pandemic infectious disease transmitted by the severe acute respiratory syndrome coronavirus (SARS-CoV-2). Allergists and other healthcare providers (HCPs) in the field of allergies and associated airway diseases are on the front line, taking care of patients potentially infected with SARS-CoV-2. Hence, strategies and practices to minimize risks of infection for both HCPs and treated patients have to be developed and followed by allergy clinics.

METHOD: The scientific information on COVID-19 was analysed by a literature search in MEDLINE, PubMed, the National and International Guidelines from the European Academy of Allergy and Clinical Immunology (EAACI), the Cochrane Library, and the internet.

RESULTS: Based on the diagnostic and treatment standards developed by EAACI, on international information regarding COVID-19, on guidelines of the World Health Organization (WHO) and other international organizations, and on previous experience, a panel of experts including clinicians, psychologists, IT experts, and basic scientists along with EAACI and the "Allergic Rhinitis and its Impact on Asthma (ARIA)" initiative have developed recommendations for the optimal management of allergy clinics during the current COVID-19 pandemic. These recommendations are grouped into nine sections on different relevant aspects for the care of patients with allergies.

CONCLUSIONS: This international Position Paper provides recommendations on operational plans and procedures to maintain high standards in the daily clinical care of allergic patients while ensuring the necessary safety measures in the current COVID-19 pandemic.},
}

Allergists
COVID-19/*epidemiology/prevention & control
Health Personnel
Humans
Hypersensitivity/diagnosis/*therapy
Information Technology
Patient Care Team
*SARS-CoV-2
Triage

@article {pmid32513287,
year = {2020},
author = {Campanile, FC and Podda, M and Arezzo, A and Botteri, E and Sartori, A and Guerrieri, M and Cassinotti, E and Muttillo, I and Pisano, M and Brachet Contul, R and D'Ambrosio, G and Cuccurullo, D and Bergamini, C and Allaix, ME and Caracino, V and Petz, WL and Milone, M and Silecchia, G and Anania, G and Agrusa, A and Di Saverio, S and Casarano, S and Cicala, C and Narilli, P and Federici, S and Carlini, M and Paganini, A and Bianchi, PP and Salaj, A and Mazzari, A and Meniconi, RL and Puzziello, A and Terrosu, G and De Simone, B and Coccolini, F and Catena, F and Agresta, F},
title = {Acute cholecystitis during COVID-19 pandemic: a multisocietary position statement.},
journal = {World journal of emergency surgery : WJES},
volume = {15},
number = {1},
pages = {38},
pmid = {32513287},
issn = {1749-7922},
mesh = {Betacoronavirus ; COVID-19 ; Cholecystectomy/methods/*standards ; Cholecystitis, Acute/*surgery/virology ; Coronavirus Infections/*complications/virology ; Humans ; Infection Control/*standards ; Pandemics ; Pneumonia, Viral/*complications/virology ; *Practice Guidelines as Topic ; SARS-CoV-2 ; Societies, Medical ; },
abstract = {Following the spread of the infection from the new SARS-CoV2 coronavirus in March 2020, several surgical societies have released their recommendations to manage the implications of the COVID-19 pandemic for the daily clinical practice. The recommendations on emergency surgery have fueled a debate among surgeons on an international level.We maintain that laparoscopic cholecystectomy remains the treatment of choice for acute cholecystitis, even in the COVID-19 era. Moreover, since laparoscopic cholecystectomy is not more likely to spread the COVID-19 infection than open cholecystectomy, it must be organized in such a way as to be carried out safely even in the present situation, to guarantee the patient with the best outcomes that minimally invasive surgery has shown to have.},
}

Betacoronavirus
COVID-19
Cholecystectomy/methods/*standards
Cholecystitis, Acute/*surgery/virology
Coronavirus Infections/*complications/virology
Humans
Infection Control/*standards
Pandemics
Pneumonia, Viral/*complications/virology
*Practice Guidelines as Topic
SARS-CoV-2
Societies, Medical

@article {pmid32501145,
year = {2020},
author = {Linnemann, B and Bauersachs, R and Grebe, M and Klamroth, R and Müller, O and Schellong, S and Lichtenberg, M},
title = {Venous thromboembolism in patients with COVID-19 (SARS-CoV-2 infection) - a position paper of the German Society of Angiology (DGA).},
journal = {VASA. Zeitschrift fur Gefasskrankheiten},
volume = {49},
number = {4},
pages = {259-263},
doi = {10.1024/0301-1526/a000885},
pmid = {32501145},
issn = {0301-1526},
mesh = {Anticoagulants/*administration & dosage ; Betacoronavirus ; COVID-19 ; Coronavirus Infections/*complications ; Humans ; Pandemics ; Pneumonia, Viral/*complications ; SARS-CoV-2 ; *Venous Thromboembolism ; },
abstract = {As observed in other infections with a systemic inflammatory response, severe COVID-19 is associated with hypercoagulability and a prothrombotic state. Currently, there is growing evidence that pulmonary embolism and thrombosis contribute to adverse outcomes and increased mortality in critically ill patients with COVID-19. The optimal thromboprophylactic regimen for patients with COVID-19 is not known. Whereas pharmacologic thromboprophylaxis is generally recommended for all hospitalized COVID-19 patients, adequate dosing of anticoagulants remains a controversial issue. Therefore, we summarize current evidence from the available literature and, on behalf of the German Society of Angiology (DGA), we aim to provide advice to establish an improved and more uniform strategy for thromboprophylaxis in patients with COVID-19.},
}

Anticoagulants/*administration & dosage
Betacoronavirus
COVID-19
Coronavirus Infections/*complications
Humans
Pandemics
Pneumonia, Viral/*complications
SARS-CoV-2
*Venous Thromboembolism

@article {pmid32500283,
year = {2020},
author = {Stolbach, AI and Mazer-Amirshahi, M and Marino, R and Nelson, LS and Sugarman, J},
title = {ACMT Position Statement: Off-Label Prescribing during COVID-19 Pandemic.},
journal = {Journal of medical toxicology : official journal of the American College of Medical Toxicology},
volume = {16},
number = {3},
pages = {342-345},
pmid = {32500283},
issn = {1937-6995},
mesh = {Betacoronavirus/drug effects ; COVID-19 ; Coronavirus Infections/*drug therapy ; Emergency Medical Services/*standards ; Humans ; Off-Label Use/*standards/*statistics & numerical data ; Pandemics ; Pneumonia, Viral/*drug therapy ; *Practice Guidelines as Topic ; SARS-CoV-2 ; United States ; United States Food and Drug Administration ; },
}

Betacoronavirus/drug effects
COVID-19
Coronavirus Infections/*drug therapy
Emergency Medical Services/*standards
Humans
Off-Label Use/*standards/*statistics & numerical data
Pandemics
Pneumonia, Viral/*drug therapy
*Practice Guidelines as Topic
SARS-CoV-2
United States
United States Food and Drug Administration

@article {pmid32489251,
year = {2020},
author = {Ahmed, S and Barbera, L and Bartlett, SJ and Bebb, DG and Brundage, M and Bryan, S and Cheung, WY and Coburn, N and Crump, T and Cuthbertson, L and Howell, D and Klassen, AF and Leduc, S and Li, M and Mayo, NE and McKinnon, G and Olson, R and Pink, J and Robinson, JW and Santana, MJ and Sawatzky, R and Moxam, RS and Sinclair, S and Servidio-Italiano, F and Temple, W},
title = {A catalyst for transforming health systems and person-centred care: Canadian national position statement on patient-reported outcomes.},
journal = {Current oncology (Toronto, Ont.)},
volume = {27},
number = {2},
pages = {90-99},
pmid = {32489251},
issn = {1718-7729},
mesh = {Canada ; Delivery of Health Care/methods/standards/*statistics & numerical data ; Humans ; Medical Oncology/methods/standards/*statistics & numerical data ; Neoplasms/diagnosis/*therapy ; *Patient Reported Outcome Measures ; Patient-Centered Care/methods/standards/*statistics & numerical data ; Quality of Life ; },
abstract = {BACKGROUND: Patient-reported outcomes (pros) are essential to capture the patient's perspective and to influence care. Although pros and pro measures are known to have many important benefits, they are not consistently being used and there is there no Canadian pros oversight. The Position Statement presented here is the first step toward supporting the implementation of pros in the Canadian health care setting.

METHODS: The Canadian pros National Steering Committee drafted position statements, which were submitted for stakeholder feedback before, during, and after the first National Canadian Patient Reported Outcomes (canpros) scientific conference, 14-15 November 2019 in Calgary, Alberta. In addition to the stakeholder feedback cycle, a patient advocate group submitted a section to capture the patient voice.

RESULTS: The canpros Position Statement is an outcome of the 2019 canpros scientific conference, with an oncology focus. The Position Statement is categorized into 6 sections covering 4 theme areas: Patient and Families, Health Policy, Clinical Implementation, and Research. The patient voice perfectly mirrors the recommendations that the experts reached by consensus and provides an overriding impetus for the use of pros in health care.

CONCLUSIONS: Although our vision of pros transforming the health care system to be more patient-centred is still aspirational, the Position Statement presented here takes a first step toward providing recommendations in key areas to align Canadian efforts. The Position Statement is directed toward a health policy audience; future iterations will target other audiences, including researchers, clinicians, and patients. Our intent is that future versions will broaden the focus to include chronic diseases beyond cancer.},
}

Canada
Delivery of Health Care/methods/standards/*statistics & numerical data
Humans
Medical Oncology/methods/standards/*statistics & numerical data
Neoplasms/diagnosis/*therapy
*Patient Reported Outcome Measures
Patient-Centered Care/methods/standards/*statistics & numerical data
Quality of Life

@article {pmid32487434,
year = {2020},
author = {Lal, S and Van Gossum, A and Joly, F and Bozzetti, F and Cuerda, C and Lamprecht, G and Mundi, MS and Staun, M and Szczepanek, K and Wanten, G and Wheatley, C and Pironi, L and , },
title = {Considerations for the management of home parenteral nutrition during the SARS-CoV-2 pandemic: A position paper from the Home Artificial Nutrition and Chronic Intestinal Failure Special Interest Group of ESPEN.},
journal = {Clinical nutrition (Edinburgh, Scotland)},
volume = {39},
number = {7},
pages = {1988-1991},
pmid = {32487434},
issn = {1532-1983},
mesh = {Betacoronavirus ; COVID-19 ; Chronic Disease ; *Coronavirus Infections/complications/therapy ; Hospitalization ; Humans ; *Intestinal Diseases/complications/therapy ; *Pandemics ; *Parenteral Nutrition, Home ; *Pneumonia, Viral/complications/therapy ; Practice Guidelines as Topic ; SARS-CoV-2 ; },
abstract = {The management of patients with chronic intestinal failure requiring home parenteral nutrition has been and will continue to be impaired during the SARS-CoV-2 pandemic. Multidisciplinary intestinal failure teams may have to adapt their clinical approaches to home care, outpatient care as well as hospital admission and discharge in order to keep this vulnerable group of patients as safe and well as possible during the unprecedented challenges that countries are facing during the pandemic. Equally, it is important that expert advice from intestinal failure teams is available when home parenteral nutrition (HPN)-dependent patients require admission with SARS-CoV-2 infection. The Home Artificial Nutrition & Chronic Intestinal Failure Special Interest Group of the European Society for Clinical Nutrition and Metabolism (ESPEN) has developed a position paper to outline areas for intestinal failure teams to consider when managing patients with chronic intestinal failure during the SARS-CoV-2 pandemic.},
}

Betacoronavirus
COVID-19
Chronic Disease
*Coronavirus Infections/complications/therapy
Hospitalization
Humans
*Intestinal Diseases/complications/therapy
*Pandemics
*Parenteral Nutrition, Home
*Pneumonia, Viral/complications/therapy
Practice Guidelines as Topic
SARS-CoV-2

@article {pmid32473781,
year = {2020},
author = {Nicholls, SJ and Nelson, M and Astley, C and Briffa, T and Brown, A and Clark, R and Colquhoun, D and Gallagher, R and Hare, DL and Inglis, S and Jelinek, M and O'Neil, A and Tirimacco, R and Vale, M and Redfern, J},
title = {Optimising Secondary Prevention and Cardiac Rehabilitation for Atherosclerotic Cardiovascular Disease During the COVID-19 Pandemic: A Position Statement From the Cardiac Society of Australia and New Zealand (CSANZ).},
journal = {Heart, lung & circulation},
volume = {29},
number = {7},
pages = {e99-e104},
pmid = {32473781},
issn = {1444-2892},
mesh = {Australia/epidemiology ; Betacoronavirus ; COVID-19 ; *Cardiac Rehabilitation/methods/trends ; *Cardiology/methods/organization & administration/trends ; *Cardiovascular Diseases/complications/epidemiology/prevention & control ; Consensus ; *Coronavirus Infections/epidemiology/prevention & control ; Delivery of Health Care/organization & administration ; Humans ; Infection Control/*organization & administration ; New Zealand/epidemiology ; *Pandemics/prevention & control ; *Pneumonia, Viral/epidemiology/prevention & control ; SARS-CoV-2 ; *Secondary Prevention/methods/organization & administration ; Societies, Medical ; },
abstract = {BACKGROUND: The coronavirus disease 2019 (COVID-19) pandemic has introduced a major disruption to the delivery of routine health care across the world. This provides challenges for the use of secondary prevention measures in patients with established atherosclerotic cardiovascular disease (CVD). The aim of this Position Statement is to review the implications for effective delivery of secondary prevention strategies during the COVID-19 pandemic.

CHALLENGES: The COVID-19 pandemic has introduced limitations for many patients to access standard health services such as visits to health care professionals, medications, imaging and blood tests as well as attendance at cardiac rehabilitation. In addition, the pandemic is having an impact on lifestyle habits and mental health. Taken together, this has the potential to adversely impact the ability of practitioners and patients to adhere to treatment guidelines for the prevention of recurrent cardiovascular events.

RECOMMENDATIONS: Every effort should be made to deliver safe, ongoing access to health care professionals and the use of evidenced based therapies in individuals with CVD. An increase in use of a range of electronic health platforms has the potential to transform secondary prevention. Integrating research programs that evaluate the utility of these approaches may provide important insights into how to develop more optimal approaches to secondary prevention beyond the pandemic.},
}

Australia/epidemiology
Betacoronavirus
COVID-19
*Cardiac Rehabilitation/methods/trends
*Cardiology/methods/organization & administration/trends
*Cardiovascular Diseases/complications/epidemiology/prevention & control
Consensus
*Coronavirus Infections/epidemiology/prevention & control
Delivery of Health Care/organization & administration
Humans
Infection Control/*organization & administration
New Zealand/epidemiology
*Pandemics/prevention & control
*Pneumonia, Viral/epidemiology/prevention & control
SARS-CoV-2
*Secondary Prevention/methods/organization & administration
Societies, Medical

@article {pmid32467031,
year = {2020},
author = {Wahi, S and Thomas, L and Stanton, T and Taylor, A and Mahadevan, D and Evans, G and Playford, D and To, A and Davis, M and Anderson, B and Buckley, B},
title = {CSANZ Imaging Council Position Statement on Echocardiography Services During the COVID-19 Pandemic.},
journal = {Heart, lung & circulation},
volume = {29},
number = {6},
pages = {e78-e83},
pmid = {32467031},
issn = {1444-2892},
mesh = {Australia/epidemiology ; *Betacoronavirus ; COVID-19 ; Cardiology ; *Coronavirus Infections/diagnostic imaging/epidemiology ; Delivery of Health Care/*standards ; Echocardiography/*standards ; Humans ; New Zealand/epidemiology ; *Pandemics ; *Pneumonia, Viral/diagnostic imaging/epidemiology ; Positron-Emission Tomography/*standards ; Risk Assessment ; SARS-CoV-2 ; Societies, Medical ; },
abstract = {This Cardiac Society of Australia and New Zealand (CSANZ) Imaging Council Position Statement aims to guide local, regional and national clinical practice, and facilitate resource and echocardiographic service planning appropriately during the current COVID-19 global pandemic. General considerations include workforce arrangements and contingency plans, patient risk assessment for COVID-19 and level of care (personal protective equipment) for staff. Both outpatient and inpatient settings are addressed, including specific considerations in the in-patient setting including scanning protocols, screening modalities and indications for echocardiograms in the context of COVID-19 infection.},
}

Australia/epidemiology
*Betacoronavirus
COVID-19
Cardiology
*Coronavirus Infections/diagnostic imaging/epidemiology
Delivery of Health Care/*standards
Echocardiography/*standards
Humans
New Zealand/epidemiology
*Pandemics
*Pneumonia, Viral/diagnostic imaging/epidemiology
Positron-Emission Tomography/*standards
Risk Assessment
SARS-CoV-2
Societies, Medical

@article {pmid32451232,
year = {2020},
author = {Kumar, S and Haqqani, H and Wynn, G and Pathak, RK and Lipton, J and Mahajan, R and Sanders, P and Healey, S and Wilsmore, B and Mariani, JA and Thomas, SP and Weerasooriya, R and McGavigan, A and Gould, PA and Weatherley, P and Saad, N and Cowan, M and Turnbull, S and Trivic, I and Wong, M and Tonchev, I and Morton, JB and Skinner, JR and Pflaumer, A and McGuire, M and Kistler, P and Kalman, JM and , },
title = {Position Statement on the Management of Cardiac Electrophysiology and Cardiac Implantable Electronic Devices in Australia During the COVID-19 Pandemic: A Living Document.},
journal = {Heart, lung & circulation},
volume = {29},
number = {6},
pages = {e57-e68},
pmid = {32451232},
issn = {1444-2892},
mesh = {Australia/epidemiology ; *Betacoronavirus ; COVID-19 ; *Coronavirus Infections/epidemiology/physiopathology/therapy ; *Defibrillators, Implantable ; *Electrophysiologic Techniques, Cardiac ; Humans ; *Pandemics ; *Pneumonia, Viral/epidemiology/physiopathology/therapy ; SARS-CoV-2 ; },
abstract = {The COVID-19 pandemic poses a significant stress on health resources in Australia. The Heart Rhythm Council of the Cardiac Society of Australia and New Zealand aims to provide a framework for efficient resource utilisation balanced with competing risks when appropriately treating patients with cardiac arrhythmias. This document provides practical recommendations for the electrophysiology (EP) and cardiac implantable electronic devices (CIED) services in Australia. The document will be updated regularly as new evidence and knowledge is gained with time.},
}

Australia/epidemiology
*Betacoronavirus
COVID-19
*Coronavirus Infections/epidemiology/physiopathology/therapy
*Defibrillators, Implantable
*Electrophysiologic Techniques, Cardiac
Humans
*Pandemics
*Pneumonia, Viral/epidemiology/physiopathology/therapy
SARS-CoV-2

@article {pmid32425181,
year = {2020},
author = {Bonalumi, G and Di Mauro, M and Garatti, A and Barili, F and Parolari, A and Gerosa, G},
title = {[COVID-19 outbreak and Cardiac Surgery: position paper from the COVID-SICCH Task Force of the Italian Society for Cardiac Surgery].},
journal = {Giornale italiano di cardiologia (2006)},
volume = {21},
number = {6},
pages = {396-400},
doi = {10.1714/3359.33320},
pmid = {32425181},
issn = {1972-6481},
mesh = {COVID-19 ; Cardiovascular Surgical Procedures/methods/*standards ; Coronavirus Infections/*complications ; Humans ; Italy ; Pandemics ; Pneumonia, Viral/*complications ; *Practice Guidelines as Topic ; Risk Assessment ; Societies, Medical ; },
}

COVID-19
Cardiovascular Surgical Procedures/methods/*standards
Coronavirus Infections/*complications
Humans
Italy
Pandemics
Pneumonia, Viral/*complications
*Practice Guidelines as Topic
Risk Assessment
Societies, Medical

@article {pmid32418875,
year = {2020},
author = {Lal, S and Hayward, CS and De Pasquale, C and Kaye, D and Javorsky, G and Bergin, P and Atherton, JJ and Ilton, MK and Weintraub, RG and Nair, P and Rudas, M and Dembo, L and Doughty, RN and Kumarasinghe, G and Juergens, C and Bannon, PG and Bart, NK and Chow, CK and Lattimore, JD and Kritharides, L and Totaro, R and Macdonald, PS},
title = {COVID-19 and Acute Heart Failure: Screening the Critically Ill - A Position Statement of the Cardiac Society of Australia and New Zealand (CSANZ).},
journal = {Heart, lung & circulation},
volume = {29},
number = {7},
pages = {e94-e98},
pmid = {32418875},
issn = {1444-2892},
mesh = {Australia/epidemiology ; Betacoronavirus ; COVID-19 ; *Cardiology/methods/organization & administration/trends ; Consensus ; *Coronavirus Infections/epidemiology/prevention & control ; Critical Illness/therapy ; *Heart Failure/diagnosis/etiology/therapy ; Humans ; *Infection Control/methods/organization & administration ; *Myocarditis/complications/virology ; New Zealand/epidemiology ; *Pandemics/prevention & control ; Patient Care Management/*methods ; *Pneumonia, Viral/epidemiology/prevention & control ; Risk Adjustment/methods ; SARS-CoV-2 ; Societies, Medical ; },
abstract = {Up to one-third of COVID-19 patients admitted to intensive care develop an acute cardiomyopathy, which may represent myocarditis or stress cardiomyopathy. Further, while mortality in older patients with COVID-19 appears related to multi-organ failure complicating acute respiratory distress syndrome (ARDS), the cause of death in younger patients may be related to acute heart failure. Cardiac involvement needs to be considered early on in critically ill COVID-19 patients, and even after the acute respiratory phase is passing. This Statement presents a screening algorithm to better identify COVID-19 patients at risk for severe heart failure and circulatory collapse, while balancing the need to protect health care workers and preserve personal protective equipment (PPE). The significance of serum troponin levels and the role of telemetry and targeted transthoracic echocardiography (TTE) in patient investigation and management are addressed, as are fundamental considerations in the management of acute heart failure in COVID-19 patients.},
}

Australia/epidemiology
Betacoronavirus
COVID-19
*Cardiology/methods/organization & administration/trends
Consensus
*Coronavirus Infections/epidemiology/prevention & control
Critical Illness/therapy
*Heart Failure/diagnosis/etiology/therapy
Humans
*Infection Control/methods/organization & administration
*Myocarditis/complications/virology
New Zealand/epidemiology
*Pandemics/prevention & control
Patient Care Management/*methods
*Pneumonia, Viral/epidemiology/prevention & control
Risk Adjustment/methods
SARS-CoV-2
Societies, Medical

@article {pmid32418120,
year = {2020},
author = {Mazer-Amirshahi, M and Fox, ER and Farmer, BM and Stolbach, AI},
title = {ACMT Position Statement: Medication Shortages During Coronavirus Disease Pandemic.},
journal = {Journal of medical toxicology : official journal of the American College of Medical Toxicology},
volume = {16},
number = {3},
pages = {346-348},
pmid = {32418120},
issn = {1937-6995},
mesh = {Antiviral Agents/*supply & distribution/*therapeutic use ; Betacoronavirus/drug effects ; COVID-19 ; Coronavirus Infections/*drug therapy ; Humans ; Medication Systems, Hospital/*standards/*statistics & numerical data ; Pandemics ; Pneumonia, Viral/*drug therapy ; *Practice Guidelines as Topic ; SARS-CoV-2 ; },
}

Antiviral Agents/*supply & distribution/*therapeutic use
Betacoronavirus/drug effects
COVID-19
Coronavirus Infections/*drug therapy
Humans
Medication Systems, Hospital/*standards/*statistics & numerical data
Pandemics
Pneumonia, Viral/*drug therapy
*Practice Guidelines as Topic
SARS-CoV-2

@article {pmid32414880,
year = {2020},
author = {Rubin, MA and Bonnie, RJ and Epstein, L and Hemphill, C and Kirschen, M and Lewis, A and Suarez, JI and , },
title = {AAN position statement: The COVID-19 pandemic and the ethical duties of the neurologist.},
journal = {Neurology},
volume = {95},
number = {4},
pages = {167-172},
doi = {10.1212/WNL.0000000000009744},
pmid = {32414880},
issn = {1526-632X},
mesh = {COVID-19 ; Coronavirus Infections/complications/*therapy ; Health Resources ; Humans ; Nervous System Diseases/complications ; Neurologists/*ethics ; Neurology/education/*ethics ; Pandemics/*ethics ; Pneumonia, Viral/complications/*therapy ; Referral and Consultation ; Societies, Medical ; Telemedicine ; },
abstract = {Patients, clinicians, and hospitals have undergone monumental changes during the coronavirus disease 2019 (COVID-19) pandemic. This crisis has forced us to consider the obligations that we neurologists have to our individual patients as well as the greater community. By returning to our fundamental understanding of these duties, we can ensure that we are providing the most ethically appropriate contingency and crisis care possible. We recommend specific adaptations to both the inpatient and outpatient settings, as well as changes to medical and trainee education. Furthermore, we explore the daunting but potentially necessary implementation of scare resource allocation protocols. As the pandemic evolves, we will need to adapt continuously to these rapidly changing circumstances and consider both national and regional standards and variation.},
}

COVID-19
Coronavirus Infections/complications/*therapy
Health Resources
Humans
Nervous System Diseases/complications
Neurologists/*ethics
Neurology/education/*ethics
Pandemics/*ethics
Pneumonia, Viral/complications/*therapy
Referral and Consultation
Societies, Medical
Telemedicine

@article {pmid32404302,
year = {2020},
author = {Chieffo, A and Stefanini, GG and Price, S and Barbato, E and Tarantini, G and Karam, N and Moreno, R and Buchanan, GL and Gilard, M and Halvorsen, S and Huber, K and James, S and Neumann, FJ and Möllmann, H and Roffi, M and Tavazzi, G and Ferré, JM and Windecker, S and Dudek, D and Baumbach, A},
title = {EAPCI Position Statement on Invasive Management of Acute Coronary Syndromes during the COVID-19 pandemic.},
journal = {EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology},
volume = {16},
number = {3},
pages = {233-246},
doi = {10.4244/EIJY20M05_01},
pmid = {32404302},
issn = {1969-6213},
mesh = {Acute Coronary Syndrome/*therapy ; Algorithms ; Betacoronavirus ; COVID-19 ; Cardiology/*standards ; *Coronavirus Infections ; Europe ; Humans ; *Pandemics ; *Pneumonia, Viral ; SARS-CoV-2 ; },
abstract = {The coronavirus disease 2019 (COVID-19) pandemic poses an unprecedented challenge to healthcare worldwide. The infection can be life threatening and require intensive care treatment. The transmission of the disease poses a risk to both patients and healthcare workers. The number of patients requiring hospital admission and intensive care may overwhelm health systems and negatively affect standard care for patients presenting with conditions needing emergency interventions. This position statements aims to assist cardiologists in the invasive management of acute coronary syndrome (ACS) patients in the context of the COVID-19 pandemic. To that end, we assembled a panel of interventional cardiologists and acute cardiac care specialists appointed by the European Association of Percutaneous Cardiovascular Interventions (EAPCI) and from the Acute Cardiovascular Care Association (ACVC) and included the experience from the first and worst affected areas in Europe. Modified diagnostic and treatment algorithms are proposed to adapt evidence-based protocols for this unprecedented challenge. Various clinical scenarios, as well as management algorithms for patients with a diagnosed or suspected COVID-19 infection, presenting with ST- and non-ST-segment elevation ACS are described. In addition, we address the need for re-organization of ACS networks, with redistribution of hub and spoke hospitals, as well as for in-hospital reorganization of emergency rooms and cardiac units, with examples coming from multiple European countries. Furthermore, we provide a guidance to reorganization of catheterization laboratories and, importantly, measures for protection of healthcare providers involved with invasive procedures.},
}

Acute Coronary Syndrome/*therapy
Algorithms
Betacoronavirus
COVID-19
Cardiology/*standards
*Coronavirus Infections
Europe
Humans
*Pandemics
*Pneumonia, Viral
SARS-CoV-2

@article {pmid32381517,
year = {2020},
author = {Klein, JD and Koletzko, B and El-Shabrawi, MH and Hadjipanayis, A and Thacker, N and Bhutta, Z},
title = {Promoting and supporting children's health and healthcare during COVID-19 - International Paediatric Association Position Statement.},
journal = {Archives of disease in childhood},
volume = {105},
number = {7},
pages = {620-624},
doi = {10.1136/archdischild-2020-319370},
pmid = {32381517},
issn = {1468-2044},
mesh = {Adolescent ; Betacoronavirus/*pathogenicity ; COVID-19 ; Child ; *Child Health ; Child, Preschool ; Consensus ; Coronavirus Infections/*prevention & control ; Health Promotion/*organization & administration ; Humans ; Infant ; Infant, Newborn ; Pandemics/*prevention & control ; *Pediatrics ; Pneumonia, Viral/*prevention & control ; Practice Guidelines as Topic ; *Public Health ; SARS-CoV-2 ; World Health Organization ; },
}

Adolescent
Betacoronavirus/*pathogenicity
COVID-19
Child
*Child Health
Child, Preschool
Consensus
Coronavirus Infections/*prevention & control
Health Promotion/*organization & administration
Humans
Infant
Infant, Newborn
Pandemics/*prevention & control
*Pediatrics
Pneumonia, Viral/*prevention & control
Practice Guidelines as Topic
*Public Health
SARS-CoV-2
World Health Organization

@article {pmid32374440,
year = {2020},
author = {Farrell, TW and Ferrante, LE and Brown, T and Francis, L and Widera, E and Rhodes, R and Rosen, T and Hwang, U and Witt, LJ and Thothala, N and Liu, SW and Vitale, CA and Braun, UK and Stephens, C and Saliba, D},
title = {AGS Position Statement: Resource Allocation Strategies and Age-Related Considerations in the COVID-19 Era and Beyond.},
journal = {Journal of the American Geriatrics Society},
volume = {68},
number = {6},
pages = {1136-1142},
pmid = {32374440},
issn = {1532-5415},
support = {K76 AG054862/AG/NIA NIH HHS/United States ; K76 AG054866/AG/NIA NIH HHS/United States ; K76 AG057023/AG/NIA NIH HHS/United States ; UL1 TR001863/TR/NCATS NIH HHS/United States ; },
mesh = {Aged ; Aged, 80 and over ; *Betacoronavirus ; COVID-19 ; *Coronavirus Infections ; Female ; Geriatrics/*standards ; Health Care Rationing/*standards ; *Health Planning Guidelines ; Humans ; Male ; *Pandemics ; *Pneumonia, Viral ; SARS-CoV-2 ; United States/epidemiology ; },
abstract = {Coronavirus disease 2019 (COVID-19) continues to impact older adults disproportionately, from severe illness and hospitalization to increased mortality risk. Concurrently, concerns about potential shortages of healthcare professionals and health supplies to address these needs have focused attention on how resources are ultimately allocated and used. Some strategies misguidedly use age as an arbitrary criterion, inappropriately disfavoring older adults. This statement represents the official policy position of the American Geriatrics Society (AGS). It is intended to inform stakeholders including hospitals, health systems, and policymakers about ethical considerations to consider when developing strategies for allocating scarce resources during an emergency involving older adults. Members of the AGS Ethics Committee collaborated with interprofessional experts in ethics, law, nursing, and medicine (including geriatrics, palliative care, emergency medicine, and pulmonology/critical care) to conduct a structured literature review and examine relevant reports. The resulting recommendations defend a particular view of distributive justice that maximizes relevant clinical factors and deemphasizes or eliminates factors placing arbitrary, disproportionate weight on advanced age. The AGS positions include (1) avoiding age per se as a means for excluding anyone from care; (2) assessing comorbidities and considering the disparate impact of social determinants of health; (3) encouraging decision makers to focus primarily on potential short-term (not long-term) outcomes; (4) avoiding ancillary criteria such as "life-years saved" and "long-term predicted life expectancy" that might disadvantage older people; (5) forming and staffing triage committees tasked with allocating scarce resources; (6) developing institutional resource allocation strategies that are transparent and applied uniformly; and (7) facilitating appropriate advance care planning. The statement includes recommendations that should be immediately implemented to address resource allocation strategies during COVID-19, aligning with AGS positions. The statement also includes recommendations for post-pandemic review. Such review would support revised strategies to ensure that governments and institutions have equitable emergency resource allocation strategies, avoid future discriminatory language and practice, and have appropriate guidance to develop national frameworks for emergent resource allocation decisions. J Am Geriatr Soc 68:1136-1142, 2020.},
}

Aged
Aged, 80 and over
*Betacoronavirus
COVID-19
*Coronavirus Infections
Female
Geriatrics/*standards
Health Care Rationing/*standards
*Health Planning Guidelines
Humans
Male
*Pandemics
*Pneumonia, Viral
SARS-CoV-2
United States/epidemiology

@article {pmid32371055,
year = {2020},
author = {Lavinsky, J and Kosugi, EM and Baptistella, E and Roithmann, R and Dolci, E and Ribeiro, TK and Rossini, B and Romano, FR and Maunsell, RCK and Mitre, EI and Imamura, R and Hachiya, A and Chone, CT and Watanabe, LMN and Fornazieri, MA and Lessa, MM and Sant'Anna, GD},
title = {An update on COVID-19 for the otorhinolaryngologist - a Brazilian Association of Otolaryngology and Cervicofacial Surgery (ABORL-CCF) Position Statement.},
journal = {Brazilian journal of otorhinolaryngology},
volume = {86},
number = {3},
pages = {273-280},
pmid = {32371055},
issn = {1808-8686},
mesh = {*Betacoronavirus ; COVID-19 ; Coronavirus Infections/*prevention & control ; Humans ; Infectious Disease Transmission, Patient-to-Professional/prevention & control ; Otolaryngology/*standards ; Pandemics/*prevention & control ; Personal Protective Equipment/*standards ; Pneumonia, Viral/*prevention & control ; Practice Guidelines as Topic ; Practice Patterns, Physicians' ; SARS-CoV-2 ; Societies, Medical ; },
abstract = {INTRODUCTION: We are facing a pandemic with a great impact worldwide, as a result of the rapid spread of the novel coronavirus (COVID-19). The medical community is still getting to know behavior of this virus and the consequences from a population point of view. All this knowledge is extremely dynamic, so some behaviors are still not well established. Otorhinolaryngologists have a central role in the management of this situation, in which they must assess the patient, avoid contamination to and by health professionals and other patients. Thus, the recommendations of the Brazilian Association of Otorhinolaryngology and Cervical-Facial Surgery (ABORL-CCF) have the main objective of reducing the spread of the new coronavirus during otorhinolaryngological care and assisting in the management of these patients.

METHODS: Review of the main recommendations of national and international scientific societies, decisions by government agencies and class councils. The topics will be related to the general aspects of COVID-19, personal protective equipment, care in patient assistance, endoscopic exam routines and the management of sinonasal, otological and pediatric evaluations related to COVID-19.

RESULTS: The use of personal protective equipment is considered crucial in routine ENT care. We recommend postponing appointments, exams and elective surgeries to reduce the spread of COVID-19. Similarly, we recommend changing routines in several areas of otolaryngology. Additionally, guidance is provided on the use of telemedicine resources during the pandemic period.

CONCLUSIONS: We are still at the beginning of the COVID-19 pandemic and scientific evidence is still scarce and incomplete, so these ABORL-CCF recommendations for otorhinolaryngologists may be updated based on new knowledge and the pattern of the new coronavirus spread.},
}

*Betacoronavirus
COVID-19
Coronavirus Infections/*prevention & control
Humans
Infectious Disease Transmission, Patient-to-Professional/prevention & control
Otolaryngology/*standards
Pandemics/*prevention & control
Personal Protective Equipment/*standards
Pneumonia, Viral/*prevention & control
Practice Guidelines as Topic
Practice Patterns, Physicians'
SARS-CoV-2
Societies, Medical

@article {pmid32323287,
year = {2020},
author = {Pfeifer, M and Ewig, S and Voshaar, T and Randerath, W and Bauer, T and Geiseler, J and Dellweg, D and Westhoff, M and Windisch, W and Schönhofer, B and Kluge, S and Lepper, PM},
title = {[Position Paper for the State of the Art Application of Respiratory Support in Patients with COVID-19 - German Respiratory Society].},
journal = {Pneumologie (Stuttgart, Germany)},
volume = {74},
number = {6},
pages = {337-357},
pmid = {32323287},
issn = {1438-8790},
mesh = {Berlin ; Betacoronavirus ; COVID-19 ; *Continuous Positive Airway Pressure/standards ; Coronavirus Infections/complications/epidemiology ; Humans ; Intubation, Intratracheal ; Lung/physiopathology/virology ; Noninvasive Ventilation/*methods ; Pandemics ; Pneumonia, Viral/complications/epidemiology ; *Positive-Pressure Respiration ; *Practice Guidelines as Topic ; Pulmonary Edema/etiology/*therapy ; Respiratory Distress Syndrome/etiology/*therapy ; Respiratory Insufficiency/prevention & control/*therapy ; SARS-CoV-2 ; Societies, Medical ; },
abstract = {Against the background of the pandemic caused by infection with the SARS-CoV-2, the German Society for Pneumology and Respiratory Medicine (DGP e.V.), in cooperation with other associations, has designated a team of experts in order to answer the currently pressing questions about therapy strategies in dealing with COVID-19 patients suffering from acute respiratory insufficiency (ARI).The position paper is based on the current knowledge that is evolving daily. Many of the published and cited studies require further review, also because many of them did not undergo standard review processes.Therefore, this position paper is also subject to a continuous review process and will be further developed in cooperation with the other professional societies.This position paper is structured into the following five topics:1. Pathophysiology of acute respiratory insufficiency in patients without immunity infected with SARS-CoV-22. Temporal course and prognosis of acute respiratory insufficiency during the course of the disease3. Oxygen insufflation, high-flow oxygen, non-invasive ventilation and invasive ventilation with special consideration of infectious aerosol formation4. Non-invasive ventilation in ARI5. Supply continuum for the treatment of ARIKey points have been highlighted as core statements and significant observations. Regarding the pathophysiological aspects of acute respiratory insufficiency (ARI), the pulmonary infection with SARS-CoV-2 COVID-19 runs through three phases: early infection, pulmonary manifestation and severe hyperinflammatory phase.There are differences between advanced COVID-19-induced lung damage and those changes seen in Acute Respiratory Distress Syndromes (ARDS) as defined by the Berlin criteria. In a pathophysiologically plausible - but currently not yet histopathologically substantiated - model, two types (L-type and H-type) are distinguished, which correspond to an early and late phase. This distinction can be taken into consideration in the differential instrumentation in the therapy of ARI.The assessment of the extent of ARI should be carried out by an arterial or capillary blood gas analysis under room air conditions and must include the calculation of the oxygen supply (measured from the variables of oxygen saturation, the Hb value, the corrected values of the Hüfner number and the cardiac output). In principle, aerosols can cause transmission of infectious viral particles. Open systems or leakage systems (so-called vented masks) can prevent the release of respirable particles. Procedures in which the invasive ventilation system must be opened, and endotracheal intubation must be carried out are associated with an increased risk of infection.The protection of personnel with personal protective equipment should have very high priority because fear of contagion must not be a primary reason for intubation. If the specifications for protective equipment (eye protection, FFP2 or FFP-3 mask, gown) are adhered to, inhalation therapy, nasal high-flow (NHF) therapy, CPAP therapy or NIV can be carried out according to the current state of knowledge without increased risk of infection to the staff. A significant proportion of patients with respiratory failure presents with relevant hypoxemia, often also caused by a high inspiratory oxygen fraction (FiO2) including NHF, and this hypoxemia cannot be not completely corrected. In this situation, CPAP/NIV therapy can be administered under use of a mouth and nose mask or a respiratory helmet as therapy escalation, as long as the criteria for endotracheal intubation are not fulfilled.In acute hypoxemic respiratory insufficiency, NIV should be performed in an intensive care unit or in a comparable unit by personnel with appropriate expertise. Under CPAP/NIV, a patient can deteriorate rapidly. For this reason, continuous monitoring with readiness to carry out intubation must be ensured at all times. If CPAP/NIV leads to further progression of ARI, intubation and subsequent invasive ventilation should be carried out without delay if no DNI order is in place.In the case of patients in whom invasive ventilation, after exhausting all guideline-based measures, is not sufficient, extracorporeal membrane oxygenation procedure (ECMO) should be considered to ensure sufficient oxygen supply and to remove CO2.},
}

Berlin
Betacoronavirus
COVID-19
*Continuous Positive Airway Pressure/standards
Coronavirus Infections/complications/epidemiology
Humans
Intubation, Intratracheal
Lung/physiopathology/virology
Noninvasive Ventilation/*methods
Pandemics
Pneumonia, Viral/complications/epidemiology
*Positive-Pressure Respiration
*Practice Guidelines as Topic
Pulmonary Edema/etiology/*therapy
Respiratory Distress Syndrome/etiology/*therapy
Respiratory Insufficiency/prevention & control/*therapy
SARS-CoV-2
Societies, Medical

@article {pmid32320138,
year = {2021},
author = {Sadeghipour, P and Talasaz, AH and Eslami, V and Geraiely, B and Vojdanparast, M and Sedaghat, M and Moosavi, AF and Alipour-Parsa, S and Aminian, B and Firouzi, A and Ghaffari, S and Ghasemi, M and Saleh, DK and Khosravi, A and Kojuri, J and Noohi, F and Pourhosseini, H and Salarifar, M and Salehi, MR and Sezavar, H and Shabestari, M and Soleimani, A and Tabarsi, P and Parsa, AFZ and Abdi, S},
title = {Management of ST-segment-elevation myocardial infarction during the coronavirus disease 2019 (COVID-19) outbreak: Iranian"247" National Committee's position paper on primary percutaneous coronary intervention.},
journal = {Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions},
volume = {97},
number = {3},
pages = {E346-E351},
pmid = {32320138},
issn = {1522-726X},
mesh = {Algorithms ; COVID-19/*epidemiology/*prevention & control/transmission ; Humans ; Infection Control/*organization & administration ; Iran/epidemiology ; *Percutaneous Coronary Intervention ; ST Elevation Myocardial Infarction/*therapy ; },
abstract = {World Health Organization has designated coronavirus disease 2019 (COVID-19) as a pandemic. During the past several weeks, a considerable burden has been imposed on the Iranian's healthcare system. The present document reviewed the latest evidence and expert opinion regarding the management of ST-segment-elevation myocardial infarction during the outbreak of COVID-19 and outlines a practical algorithm for it.},
}

Algorithms
COVID-19/*epidemiology/*prevention & control/transmission
Humans
Infection Control/*organization & administration
Iran/epidemiology
*Percutaneous Coronary Intervention
ST Elevation Myocardial Infarction/*therapy

@article {pmid32311380,
year = {2020},
author = {Maillard, JY and Bloomfield, SF and Courvalin, P and Essack, SY and Gandra, S and Gerba, CP and Rubino, JR and Scott, EA},
title = {Reducing antibiotic prescribing and addressing the global problem of antibiotic resistance by targeted hygiene in the home and everyday life settings: A position paper.},
journal = {American journal of infection control},
volume = {48},
number = {9},
pages = {1090-1099},
pmid = {32311380},
issn = {1527-3296},
mesh = {Anti-Bacterial Agents/*adverse effects ; Bacterial Infections/drug therapy ; *Drug Resistance, Bacterial ; Global Health/*standards ; Humans ; Hygiene/*standards ; Prescription Drug Overuse/*prevention & control ; Sanitation/standards ; },
abstract = {Antimicrobial resistance (AMR) continues to threaten global health. Although global and national AMR action plans are in place, infection prevention and control is primarily discussed in the context of health care facilities with home and everyday life settings barely addressed. As seen with the recent global SARS-CoV-2 pandemic, everyday hygiene measures can play an important role in containing the threat from infectious microorganisms. This position paper has been developed following a meeting of global experts in London, 2019. It presents evidence that home and community settings are important for infection transmission and also the acquisition and spread of AMR. It also demonstrates that the targeted hygiene approach offers a framework for maximizing protection against colonization and infections, thereby reducing antibiotic prescribing and minimizing selection pressure for the development of antibiotic resistance. If combined with the provision of clean water and sanitation, targeted hygiene can reduce the circulation of resistant bacteria in homes and communities, regardless of a country's Human Development Index (overall social and economic development). Achieving a reduction of AMR strains in health care settings requires a mirrored reduction in the community. The authors call upon national and international policy makers, health agencies, and health care professionals to further recognize the importance of targeted hygiene in the home and everyday life settings for preventing and controlling infection, in a unified quest to tackle AMR.},
}

Anti-Bacterial Agents/*adverse effects
Bacterial Infections/drug therapy
*Drug Resistance, Bacterial
Global Health/*standards
Humans
Hygiene/*standards
Prescription Drug Overuse/*prevention & control
Sanitation/standards

@article {pmid32243317,
year = {2020},
author = {Garcia-Castrillo, L and Petrino, R and Leach, R and Dodt, C and Behringer, W and Khoury, A and Sabbe, M},
title = {European Society For Emergency Medicine position paper on emergency medical systems' response to COVID-19.},
journal = {European journal of emergency medicine : official journal of the European Society for Emergency Medicine},
volume = {27},
number = {3},
pages = {174-177},
pmid = {32243317},
issn = {1473-5695},
mesh = {Betacoronavirus ; COVID-19 ; Coronavirus Infections/*diagnosis/*therapy ; Emergency Medicine/*standards ; Emergency Service, Hospital/*organization & administration ; Humans ; Infection Control ; Pandemics ; Patient Isolation ; Personal Protective Equipment/supply & distribution ; Pneumonia, Viral/*diagnosis/*therapy ; SARS-CoV-2 ; Triage ; },
abstract = {The 2019 novel coronavirus acute respiratory epidemic is creating a stressed situation in all the health systems of the affected countries. Emergency medical systems and specifically the emergency departments as the front line of the health systems are suffering from overload and severe working conditions, the risk of contagion and transmission of the health professionals adds a substantial burden to their daily work. Under the perspective of European Society For Emergency Medicine, the recommendations provided by the health authorities are reviewed focus on the emergency department's activity.},
}

Betacoronavirus
COVID-19
Coronavirus Infections/*diagnosis/*therapy
Emergency Medicine/*standards
Emergency Service, Hospital/*organization & administration
Humans
Infection Control
Pandemics
Patient Isolation
Personal Protective Equipment/supply & distribution
Pneumonia, Viral/*diagnosis/*therapy
SARS-CoV-2
Triage

@article {pmid32223063,
year = {2020},
author = {Tarantini, G and Fraccaro, C and Chieffo, A and Marchese, A and Tarantino, FF and Rigattieri, S and Limbruno, U and Mauro, C and La Manna, A and Castiglioni, B and Longoni, M and Berti, S and Greco, F and Musumeci, G and Esposito, G and , },
title = {Italian Society of Interventional Cardiology (GISE) position paper for Cath lab-specific preparedness recommendations for healthcare providers in case of suspected, probable or confirmed cases of COVID-19.},
journal = {Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions},
volume = {96},
number = {4},
pages = {839-843},
pmid = {32223063},
issn = {1522-726X},
mesh = {*Betacoronavirus ; COVID-19 ; *Cardiac Catheterization ; Clinical Protocols ; Coronavirus Infections/epidemiology/*prevention & control/transmission ; Humans ; Infection Control/*organization & administration ; Italy ; Pandemics/*prevention & control ; Pneumonia, Viral/epidemiology/*prevention & control/transmission ; Practice Guidelines as Topic ; SARS-CoV-2 ; Societies, Medical ; },
abstract = {COVID-19 pandemic raised the issue to guarantee the proper level of care to patients with acute cardiovascular diseases and concomitant suspected or confirmed COVID-19 and, in the meantime safety and protection of healthcare providers. The aim of this position paper is to provide standards to healthcare facilities and healthcare providers on infection prevention and control measures during the management of suspected and confirmed cases of 2019-nCoV infection accessing in cath-lab. The document represents the view of the Italian Society of Interventional Cardiology (GISE), and it is based on recommendations from the main World and European Health Organizations (WHO, and ECDC) as well as from the Italian Society of Anesthesia, Analgesia, Resuscitation and Intensive Care (SIAARTI).},
}

*Betacoronavirus
COVID-19
*Cardiac Catheterization
Clinical Protocols
Coronavirus Infections/epidemiology/*prevention & control/transmission
Humans
Infection Control/*organization & administration
Italy
Pandemics/*prevention & control
Pneumonia, Viral/epidemiology/*prevention & control/transmission
Practice Guidelines as Topic
SARS-CoV-2
Societies, Medical

@article {pmid32207189,
year = {2020},
author = {Poon, LC and Abramowicz, JS and Dall'Asta, A and Sande, R and Ter Haar, G and Maršal, K and Brezinka, C and Miloro, P and Basseal, J and Westerway, SC and Abu-Rustum, RS and Lees, C},
title = {ISUOG Safety Committee Position Statement on safe performance of obstetric and gynecological scans and equipment cleaning in context of COVID-19.},
journal = {Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology},
volume = {55},
number = {5},
pages = {709-712},
doi = {10.1002/uog.22027},
pmid = {32207189},
issn = {1469-0705},
mesh = {*Betacoronavirus ; COVID-19 ; *Coronavirus Infections/prevention & control/transmission ; *Diagnostic Techniques, Obstetrical and Gynecological/standards ; Equipment Safety/*standards ; Female ; Genital Diseases, Female/diagnosis ; Humans ; *Hygiene/standards ; *Pandemics/prevention & control ; *Pneumonia, Viral/prevention & control/transmission ; Pregnancy ; SARS-CoV-2 ; Societies, Medical ; },
}

*Betacoronavirus
COVID-19
*Coronavirus Infections/prevention & control/transmission
*Diagnostic Techniques, Obstetrical and Gynecological/standards
Equipment Safety/*standards
Female
Genital Diseases, Female/diagnosis
Humans
*Hygiene/standards
*Pandemics/prevention & control
*Pneumonia, Viral/prevention & control/transmission
Pregnancy
SARS-CoV-2
Societies, Medical

@article {pmid41401760,
year = {2025},
author = {Blanco, J and Ferreras, M and Cosido, O},
title = {Predictive modeling of hospital emergency department demand using artificial intelligence: A systematic review.},
journal = {International journal of medical informatics},
volume = {207},
number = {},
pages = {106215},
doi = {10.1016/j.ijmedinf.2025.106215},
pmid = {41401760},
issn = {1872-8243},
abstract = {BACKGROUND: Accurately forecasting patient arrivals in hospital emergency departments (EDs) is critical for hospital capacity and planning and clinical decision-making. Artificial intelligence (AI), particularly machine learning (ML) and deep learning (DL), has shown promising performance over traditional time series approaches. However, the extent to which these models are validated and generalizable remains uncertain.

OBJECTIVE: To systematically review the literature on predictive models for hospital ED demand forecasting, focusing on algorithms used, internal and external variables, validation strategies and limitations pre- and post-pandemic developments.

METHODS: A systematic literature review (SLR) was conducted following PRISMA guidelines. Five databases (PubMed, IEEE, Springer, ScienceDirect, ACM) were searched for peer-reviewed articles published between January 2019 and July 2025. Eligible studies applied predictive algorithms - excluding those focused on COVID-19 - to forecast ED visits. Extracted data included modeling approaches, feature types, evaluation metrics, and validation methods.

RESULTS: Eleven studies met the inclusion criteria. Classical models such as ARIMA and SARIMA remain in use, but ML (e.g., XGBoost, Random Forest) and DL (e.g., LSTM, CNN) showed higher predictive accuracy, especially with high-dimensional, nonlinear data. Incorporating external variables-such as weather (temperature, humidity, wind), air quality, and calendar events-consistently improved performance. Common metrics included Mean Absolute Error (MAE), Root Mean Squared Error (RMSE), and Mean Absolute Percentage Error (MAPE), with MAPE ranging from 3 % to 18 %. Few studies performed external validation, and only a minority employed explainable AI methods (e.g., SHAP) to address interpretability.

CONCLUSIONS: AI-based models offer strong potential for ED demand forecasting, particularly when integrating environmental and temporal features. However, limited external validation and lack of interpretability remain significant barriers to clinical adoption. Future research should prioritize multicenter validation, standardized evaluation, and explainable AI to support reliable, transparent, and scalable use in hospital emergency departments.},
}

@article {pmid41401413,
year = {2025},
author = {Miranda Quintero, J and Celis-Amórtegui, M and Arturo Rojas, MC and Mendoza Rosado, L and Grillo-Ardila, CF and Grillo-Ardila, EK and Ramírez-Mosquera, JJ and Lovera, LA and Ramírez-Mosquera, MJ},
title = {[Consenso de expertos en torno a la vacunación como estrategia de prevención primaria para la mujer que se encuentra en edad reproductiva, gestando o en la edad adulta].},
journal = {Revista colombiana de obstetricia y ginecologia},
volume = {76},
number = {2},
pages = {},
doi = {10.18597/rcog.4310},
pmid = {41401413},
issn = {2463-0225},
mesh = {Humans ; Female ; Pregnancy ; *Vaccination/methods ; Adult ; Colombia ; *Primary Prevention/methods ; Young Adult ; Consensus ; *Vaccines/administration & dosage ; },
abstract = {OBJETIVO: generar recomendaciones para la vacunación de la mujer, en las diferentes etapas de su vida, a fin de disminuir la posible variabilidad de su uso actual en Colombia. Materiales y métodos: el grupo desarrollador estuvo conformado por profesionales pertenecientes al área de la salud. Todos los participantes declararon por escrito sus conflictos de interés. Se formularon preguntas clínicas contestables, se hizo la graduación de los desenlaces y la pesquisa de la información se realizó en Medline/PubMed, Embase y Lilacs. La búsqueda también abarcó fuentes de literatura gris y se actualizó el 14 de mayo de 2024 sin restricciones por fecha o idioma. Se implementó la metodología GRADE (Grading of Recommendations Assessment, Development and Evaluation) para establecer la calidad de la evidencia y la fuerza de la recomendación. En virtud de las limitaciones de los estudios recuperados, y especialmente cuando se trató de limitaciones en la aplicabilidad de la evidencia, se acudió a la opinión de expertos. Se realizó consenso formal acorde con la metodología RAND/UCLA (RAND Corporation/Universidad de California en Los Ángeles). Previo a la publicación, el documento fue objeto de revisión por pares.

RESULTADOS: se desarrollaron las siguientes recomendaciones: • El grupo desarrollador sugiere que las mujeres no inmunes a las paperas, sarampión o rubeola (p. ej., IgG negativo) sean vacunadas durante el periodo preconcepcional. Calidad de la evidencia: baja ⨁⨁◯◯ • El grupo desarrollador sugiere que todas las mujeres en periodo preconcepcional se vacunen contra la varicela si no tienen inmunidad natural confirmada (p. ej., anticuerpos IgG negativo para el virus varicela zóster). Calidad de la evidencia: muy baja ⨁◯◯◯ • El grupo desarrollador sugiere que las mujeres que viven en regiones endémicas para fiebre amarilla se vacunen durante el periodo preconcepcional si no han sido previamente inmunizadas. Calidad de la evidencia: muy baja ⨁◯◯◯ • El grupo desarrollador sugiere vacunar adolescentes y adultas jóvenes con la vacuna para el virus del papiloma humano (VPH), de 3 dosis (0,2 y 6 meses) con el fin de reducir la incidencia y mortalidad por cáncer cervical. Calidad de evidencia: moderada ⨁⨁⨁◯ • El grupo desarrollador sugiere que las mujeres gestantes sean inmunizadas contra el tétano, la difteria y la tos ferina durante la gestación, con el objetivo de reducir el riesgo de infección en la madre y el neonato. Calidad de la evidencia: baja ⨁⨁◯◯ • El grupo desarrollador sugiere la vacunación contra la influenza a cualquier edad gestacional, con el objetivo de reducir el riesgo de infección en la madre y el neonato hasta los seis meses de edad. Calidad de la evidencia: muy baja ⨁◯◯◯ • El grupo desarrollador sugiere la vacunación materna frente al COVID-19 a cualquier edad gestacional, con el objetivo de reducir el riesgo de hospitalización y muerte de la madre y el neonato durante los primeros cuatro meses de vida. Calidad de la evidencia: muy baja ⨁◯◯◯ • El grupo desarrollador sugiere la vacunación contra el virus sincitial respiratorio (VSR) en mujeres gestantes, con el objetivo de reducir el riesgo de hospitalización en el neonato. Calidad de la evidencia: muy baja ⨁◯◯◯ • El grupo desarrollador sugiere que la mujer adulta mayor se vacune contra el herpes zóster, con el fin de reducir la morbilidad asociada a esta condición. Calidad de la evidencia: moderada ⨁⨁⨁◯ • El grupo desarrollador sugiere que la mujer adulta mayor se vacune contra la influenza a fin de reducir la incidencia de infección respiratoria aguda (IRA). Calidad de la evidencia: moderada ⨁⨁⨁◯ • El grupo desarrollador sugiere que la mujer adulta mayor se vacune contra el neumococo a fin de reducir la incidencia de neumonía y enfermedad neumocócica invasora. Calidad de la evidencia: baja ⨁⨁◯◯ • El grupo desarrollador sugiere que la mujer adulta mayor se vacune contra el VSR a fin de reducir la incidencia de infección respiratoria aguda e infección respiratoria del tracto inferior. Calidad de la evidencia: baja ⨁⨁◯◯ • El grupo desarrollador sugiere que la mujer adulta mayor que vive en regiones endémicas para fiebre amarilla se vacune si no ha sido previamente inmunizada. Calidad de la evidencia: muy baja ⨁◯◯◯ Conclusiones: se recomienda la vacunación como estrategia de prevención primaria a lo largo de las diferentes etapas de la vida en la mujer. Dada la calidad de la evidencia y las serias limitaciones en la aplicabilidad de algunos estudios, especialmente en mujeres gestantes, se requieren más investigaciones que evalúen la seguridad y la efectividad de esta intervención en esta etapa de la vida.},
}

Humans
Female
Pregnancy
*Vaccination/methods
Adult
Colombia
*Primary Prevention/methods
Young Adult
Consensus
*Vaccines/administration & dosage

@article {pmid41401334,
year = {2025},
author = {Gabor, M and Schlosserova, A and Korchynska, OO},
title = {Vaccination in pregnancy: a systematic review of current evidence.},
journal = {Wiadomosci lekarskie (Warsaw, Poland : 1960)},
volume = {78},
number = {10},
pages = {2142-2146},
doi = {10.36740/WLek/213601},
pmid = {41401334},
issn = {0043-5147},
mesh = {Humans ; Pregnancy ; Female ; *COVID-19/prevention & control ; *Influenza, Human/prevention & control ; *Pregnancy Complications, Infectious/prevention & control ; *Vaccination ; *Influenza Vaccines/administration & dosage ; *COVID-19 Vaccines/administration & dosage ; *Whooping Cough/prevention & control ; *Pertussis Vaccine ; },
abstract = {OBJECTIVE: Aim: To summarize current recommendations and the state of knowledge on vaccination of pregnant women against influenza, pertussis, and Covid-19, and to highlight evidence on the efficacy and safety of vaccination during pregnancy.

PATIENTS AND METHODS: Materials and Methods: A systematic literature review of studies published between 2014 and 2024 in the PubMed, Science Direct, Google Scholar, and NCBI databases was conducted. Of the total number of 31 studies found, 10 that met our required conditions were included. The inclusion criteria were peer-reviewed articles dealing with vaccination during pregnancy. Data selection and extraction were performed in accordance with PRISMA recommendations.

CONCLUSION: Conclusions: Vaccination of pregnant women appears to be a safe and effective way to protect mothers and their offspring. Emphasis should be placed on raising awareness and education in clinical practice.},
}

Humans
Pregnancy
Female
*COVID-19/prevention & control
*Influenza, Human/prevention & control
*Pregnancy Complications, Infectious/prevention & control
*Vaccination
*Influenza Vaccines/administration & dosage
*COVID-19 Vaccines/administration & dosage
*Whooping Cough/prevention & control
*Pertussis Vaccine

@article {pmid41399268,
year = {2025},
author = {Fedorchenko, Y and Zimba, O},
title = {Ethical Use of Artificial Intelligence for Processing Medical Images.},
journal = {Journal of Korean medical science},
volume = {40},
number = {48},
pages = {e341},
doi = {10.3346/jkms.2025.40.e341},
pmid = {41399268},
issn = {1598-6357},
mesh = {Humans ; *Artificial Intelligence/ethics ; *Image Processing, Computer-Assisted/ethics ; *Diagnostic Imaging/ethics ; COVID-19 ; Algorithms ; Deep Learning ; SARS-CoV-2 ; },
abstract = {Artificial intelligence (AI) tools employ prompts and algorithms to perform tasks that typically require human expertise, hypothesis formulation, and critical evaluation. AI enables rapid analysis of complex imaging data, automates segmentation and lesion detection, and supports real-time image-guided interventions. Deep learning architectures (CNNs, RNNs, U-Net, and transformer-based models) facilitate advanced image classification, reconstruction, and interpretation, achieving clinical accuracies above 90% in multiple domains, including coronavirus disease 2019, oncology, and rheumatology. Generative AI platforms (MedGAN, StyleGAN, CycleGAN, SinGAN-Seg) further support synthetic image creation and dataset augmentation, mitigating data scarcity while preserving patient privacy. However, the integration of AI in healthcare presents significant ethical challenges. Key concerns include algorithmic bias, patient privacy, transparency, accountability, and equitable access. Biases-such as annotation, automation, confirmation, demographic, and feedback-loop bias-can compromise diagnostic reliability and patient outcomes. Ethical deployment requires rigorous data governance, informed consent, anonymization, standardized validation frameworks, human oversight, and regulatory compliance. Maintaining interpretability and transparency of AI outputs is essential for clinical decision-making, while professional training and AI literacy are critical to mitigate overreliance and ensure patient safety.},
}

Humans
*Artificial Intelligence/ethics
*Image Processing, Computer-Assisted/ethics
*Diagnostic Imaging/ethics
COVID-19
Algorithms
Deep Learning
SARS-CoV-2

@article {pmid41398580,
year = {2025},
author = {Manarte, R and Henriques, MR},
title = {From exceptionalism to universal testing: an historical review of HIV testing in Portugal.},
journal = {BMC public health},
volume = {25},
number = {1},
pages = {4251},
pmid = {41398580},
issn = {1471-2458},
mesh = {Portugal/epidemiology ; Humans ; *HIV Infections/diagnosis ; *HIV Testing/history ; *Health Policy ; History, 20th Century ; History, 21st Century ; *Mass Screening/history ; *Universal Health Care ; },
abstract = {INTRODUCTION: Portugal has made significant progress over the last 40 years in the response against the Human Immunodeficiency Virus (HIV) infection and the Acquired Immunodeficiency Syndrome (AIDS). However, as of 2021, it remained one of the three Western European countries with the highest rates of new HIV infections and AIDS cases. Initially shaped by HIV exceptionalism, Portugal began transitioning to a universal testing strategy in 2011. This study provides a historical and policy review of the evolution of HIV testing in Portugal, focusing on alignment with international guidelines and national implementation outcomes.

METHODS: We conducted a narrative policy review covering the period from 1998 to 2024. Our analysis drew on scientific literature, national health plans, surveillance reports, and international guidelines. Documents were selected through structured searches in multiple academic databases and government repositories using relevant Portuguese and English search terms. Thematically coded findings were mapped chronologically and assessed against evolving WHO and CDC recommendations.

RESULTS: Portugal gradually moved from a targeted testing approach to a more comprehensive, universal strategy. Key policy shifts occurred in 2011 and 2017, accompanied by an expansion of testing modalities, including self-testing and community-based testing. Despite these developments, implementation has been uneven. The lack of standardized protocols, limited integration into primary healthcare, and regional disparities tied to a contract-based health system have contributed to inconsistent service delivery. Additionally, testing uptake among older adults, migrants, and other key populations remains suboptimal. The COVID-19 pandemic temporarily disrupted testing services but also accelerated the use of self-testing strategies.

DISCUSSION: Portugal's experience illustrates the challenges of operationalizing universal HIV testing within a hybrid public-private healthcare system. Although policies increasingly reflect international best practices, structural barriers continue to hinder equitable implementation.

CONCLUSION: To close existing testing gaps, Portugal must strengthen implementation by standardizing procedures, improve disaggregated data collection in monitoring systems, and ensure greater integration of HIV testing in primary healthcare. Enhanced outreach to underserved populations will be critical to achieving national and international HIV prevention targets. This paper offers a historical and policy perspective to inform more equitable and effective national testing strategies.},
}

Portugal/epidemiology
Humans
*HIV Infections/diagnosis
*HIV Testing/history
*Health Policy
History, 20th Century
History, 21st Century
*Mass Screening/history
*Universal Health Care

@article {pmid41398527,
year = {2025},
author = {Maleki, F and Hosseinpour, M and Pashaei, MR and Aghdam, ME and Bahardoust, M and Delpisheh, A},
title = {Body mass index in children with newly diagnosed celiac disease: A systematic review and meta-analysis.},
journal = {European journal of pediatrics},
volume = {185},
number = {1},
pages = {18},
pmid = {41398527},
issn = {1432-1076},
mesh = {Humans ; *Celiac Disease/diagnosis/complications/diet therapy/epidemiology ; *Body Mass Index ; Child ; *Thinness/epidemiology ; Prevalence ; Diet, Gluten-Free ; *Pediatric Obesity/epidemiology ; Child, Preschool ; },
abstract = {UNLABELLED: Clinical manifestations of celiac disease (CeD) in children are often associated with malabsorption, malnutrition, and underweight. Recent evidence suggests an increased prevalence in normal-weight and obese children. Under-recognition of patients with normal or high BMI can lead to delayed diagnosis and serious complications. The present study aimed to determine the BMI status of children with CeD at diagnosis and before gluten-free diet (GFD). A systematic review and meta-analysis was conducted following the PRISMA and MOOSE guidelines and after PROSPERO registration (CRD42023390243). The information sources, including PubMed, Scopus, and Web of Science, were systematically searched through 30 September 2025 to identify relevant articles. The study's eligibility criteria included observational studies, such as retrospective, cross-sectional, and prospective designs, with participants whose CeD diagnosis was confirmed by a gastroenterologist and who reported BMI data at the time of diagnosis. Heterogeneity among studies was assessed using the I[2] statistic. Funnel plots and Egger's test were also used to examine publication bias. The risk of bias of studies was assessed using the Newcastle-Ottawa (NOS) scale. The Grading of Recommendations, Assessment, Development and Evaluation (GRADE) framework was used to determine the certainty of the evidence. Overall, 32 studies including 14,169 children with CeD were investigated. The pooled prevalence of underweight and overweight/obesity at diagnosis was 15.3% (10.8-20.4%) and 10.5% (5.7-16.4%), respectively. Subgroup analysis by WHO region revealed a marked heterogeneity (I[2] > 90%), with the highest prevalence of underweight observed in the Eastern Mediterranean Region (EMRO) (31.9%). On the other hand, the highest prevalence of overweight/obesity was observed in the European Region (EURO) (12.0%) and the Western Pacific Region (WPRO) (21.4%). A key finding was a significant difference across World Bank income groups; underweight prevalence was nearly four times higher in low- and middle-income countries (LMICs), 35.48 (24.29, 47.51), compared with high-income countries, 9.58 (6.88, 12.63). The certainty of the evidence for all pooled prevalence estimates was rated as very low due to serious inconsistency and imprecision.

CONCLUSIONS:  The prevalence of normal weight and overweight/obesity in children with celiac disease at diagnosis was higher than that of underweight, mainly in high-income countries. This finding challenges the traditional belief about the CeD and emphasizes its diagnosis in children with suspicious symptoms, regardless of their BMI status. This approach will lead to earlier diagnosis, improving clinical outcomes and quality of life for patients in the long term.

WHAT IS KNOWN: • The clinical presentation of celiac disease is evolving, and its association with underweight is inconsistent. • The structural effects of COVID-19 on the developing brain remain poorly understood due to limited pediatric imaging studies.

WHAT IS NEW: • This is the first meta-analysis focused exclusively on children, revealing that the majority (70.2%) present with a normal BMI at diagnosis. • The clinical inconsistency in BMI presentation is strongly linked to income levels; underweight prevalence is nearly four times higher in LMICs (35.5%) than in high-income countries (9.6%).},
}

Humans
*Celiac Disease/diagnosis/complications/diet therapy/epidemiology
*Body Mass Index
Child
*Thinness/epidemiology
Prevalence
Diet, Gluten-Free
*Pediatric Obesity/epidemiology
Child, Preschool

@article {pmid41397515,
year = {2025},
author = {Chen, P and Prosser, M and Phillips, B and Ellison CEng, P and Rangan, A},
title = {Accuracy and Reliability of Remote Shoulder Motion Capturing Methods: A Systematic Review and Meta-Analysis.},
journal = {Journal of shoulder and elbow surgery},
volume = {},
number = {},
pages = {},
doi = {10.1016/j.jse.2025.11.007},
pmid = {41397515},
issn = {1532-6500},
abstract = {BACKGROUND: The COVID-19 pandemic accelerated the demand for remote assessment tools in rehabilitation, especially the need for accurate and reliable technologies to measure shoulder range of motion (ROM) outside of clinical environments. Emerging tools such as smartphone apps, wearable sensors, and markerless motion capture systems are increasingly being adopted, yet their accuracy and reliability compared to reference standards remains unclear.

OBJECTIVE: To systematically evaluate the accuracy and reliability of existing remote shoulder ROM measurement technologies, quantify measurement bias, and assess their agreement with reference standards.

METHODS: A systematic review and meta-analysis was conducted on 26 studies evaluating remote ROM measurement tools. Pooled mean bias (in degrees) was calculated as the primary effect size for agreement, with reliability assessed using intraclass correlation coefficients (ICCs). Subgroup analyses were performed by motion type, technology category, population health status, and data acquisition method. Risk of bias was assessed using the QUADAS-2 tool.

RESULTS: Remote measurement methods showed a small but consistent overestimation of ROM compared to reference standards (pooled mean bias = 2.63°, 95% CI: 1.52°, 3.74°), particularly in flexion, internal rotation, and external rotation. No significant bias was observed in abduction or extension. Both IMU and non-IMU technologies demonstrated comparable levels of overestimation. Pathological populations exhibited greater variability (bias = 4.33° vs. 2.37° in healthy subjects). Self-measurements showed lower and non-significant bias compared to assessor-guided methods. Reliability was generally high, especially for test-retest assessments (ICCs > 0.90), though more variable in inter-rater and pathological settings.

CONCLUSION: Remote shoulder ROM measurement technologies tend to slightly overestimate joint angles but remain within clinically acceptable limits. These tools are reliable for tracking ROM trends and suitable for remote monitoring in clinical and research settings. However, increased variability in pathological populations warrants caution. Broader validation in diverse patient cohorts is needed to strengthen clinical implementation.},
}

@article {pmid41397310,
year = {2025},
author = {Cho, AH and Cho, SY and Kim, S and Lee, S},
title = {Targeting emerging viruses with phage display-driven engineered antibodies: Bridging molecular design and clinical application.},
journal = {Molecular aspects of medicine},
volume = {107},
number = {},
pages = {101441},
doi = {10.1016/j.mam.2025.101441},
pmid = {41397310},
issn = {1872-9452},
abstract = {Phage display (PD) is a powerful platform that accelerates the discovery and engineering of therapeutic antibodies across diverse diseases, including emerging and re-emerging viral infections. The COVID-19 pandemic highlighted the urgency for rapid and adaptable antibody development against highly mutable pathogens, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). PD technology enables the rapid and high-throughput identification, optimization, and efficient reformatting of virus-neutralizing antibodies, yielding fully PD-derived antibodies and reformatted derivatives from PD fragments without requiring convalescent samples or animal immunization. This approach supports a proactive and scalable strategy for pandemic preparedness. This review provides a comprehensive overview of PD-derived therapeutic antibodies targeting infectious diseases, focusing on approved agents and candidates in clinical or preclinical development for SARS-CoV-2. We highlight recent case studies, including our own, showing the successful application of PD in generating potent neutralizing and multispecific antibody formats. These offer functional advantages such as enhanced breadth and affinity while also serving as versatile molecular tools for elucidating viral pathogenesis and immune evasion mechanisms. Despite PD's technological strengths, the clinical advancement of PD-derived candidates has been influenced by external circumstances associated with the evolving pandemic landscape, highlighting the need to strategically leverage PD's strengths to accelerate translational outcomes in future outbreaks. This review offers a well-rounded viewpoint on PD, outlining its applications, addressing its challenges, and incorporating emerging innovations into PD workflows. These advances position PD-derived candidates as a strategic, versatile, and rapid-response platform that bridges molecular insights with clinical translation, offering a robust framework for addressing current and future infectious disease challenges.},
}

@article {pmid33909785,
year = {2021},
author = {Beck, ALS and Barberato, SH and Almeida, ALC and Grau, CRPC and Lopes, MMU and Lima, RSL and Cerci, RJ and Albricker, ACL and Barros, FS and Oliveira, AJ and Lira Filho, EB and Miglioranza, MH and Vieira, MLC and Pena, JLB and Strabelli, TMV and Bihan, DCSL and Tsutsui, JM and Rochitte, CE},
title = {Position Statement on Indications and the Safe Reintroduction of Cardiovascular Imaging Methods in the COVID-19 Scenario - 2021.},
journal = {Arquivos brasileiros de cardiologia},
volume = {116},
number = {3},
pages = {659-678},
pmid = {33909785},
issn = {1678-4170},
mesh = {Humans ; *Cardiovascular System ; *COVID-19 ; SARS-CoV-2 ; Societies, Medical ; },
}

Humans
*Cardiovascular System
*COVID-19
SARS-CoV-2
Societies, Medical

@article {pmid32472377,
year = {2020},
author = {Ganau, M and Netuka, D and Broekman, M and Zoia, C and Tsianaka, E and Schwake, M and Balak, N and Sekhar, A and Ridwan, S and Clusmann, H and , },
title = {Neurosurgeons and the fight with COVID-19: a position statement from the EANS Individual Membership Committee.},
journal = {Acta neurochirurgica},
volume = {162},
number = {8},
pages = {1777-1782},
pmid = {32472377},
issn = {0942-0940},
mesh = {Humans ; *Access to Information ; Betacoronavirus ; *Communication ; *Coronavirus Infections/epidemiology ; COVID-19 ; Europe/epidemiology ; Neurosurgeons ; Neurosurgery ; Pandemics ; *Personal Protective Equipment ; *Pneumonia, Viral/epidemiology ; SARS-CoV-2 ; Societies, Medical ; *Stress, Psychological ; },
}

Humans
*Access to Information
Betacoronavirus
*Communication
*Coronavirus Infections/epidemiology
COVID-19
Europe/epidemiology
Neurosurgeons
Neurosurgery
Pandemics
*Personal Protective Equipment
*Pneumonia, Viral/epidemiology
SARS-CoV-2
Societies, Medical
*Stress, Psychological

@article {pmid32407899,
year = {2020},
author = {Lavoué, V and Akladios, C and Gladieff, L and Classe, JM and Lécuru, F and Collinet, P},
title = {Onco-gynecologic surgery in the COVID-19 era: Risks and precautions-A position paper from FRANCOGYN, SCGP, SFCO, and SFOG.},
journal = {Journal of gynecology obstetrics and human reproduction},
volume = {49},
number = {7},
pages = {101787},
pmid = {32407899},
issn = {2468-7847},
mesh = {Female ; Humans ; Anesthesiologists ; Antineoplastic Agents/therapeutic use ; *Betacoronavirus ; Consensus ; *Coronavirus Infections/epidemiology/prevention & control/transmission ; COVID-19 ; France/epidemiology ; *Genital Neoplasms, Female/diagnosis/therapy ; *Gynecologic Surgical Procedures ; *Occupational Diseases/prevention & control ; *Pandemics/prevention & control ; Personal Protective Equipment ; *Pneumonia, Viral/epidemiology/prevention & control/transmission ; Preoperative Care/methods ; SARS-CoV-2 ; *Societies, Medical ; Surgeons ; Telemedicine ; Withholding Treatment ; },
}

Female
Humans
Anesthesiologists
Antineoplastic Agents/therapeutic use
*Betacoronavirus
Consensus
*Coronavirus Infections/epidemiology/prevention & control/transmission
COVID-19
France/epidemiology
*Genital Neoplasms, Female/diagnosis/therapy
*Gynecologic Surgical Procedures
*Occupational Diseases/prevention & control
*Pandemics/prevention & control
Personal Protective Equipment
*Pneumonia, Viral/epidemiology/prevention & control/transmission
Preoperative Care/methods
SARS-CoV-2
*Societies, Medical
Surgeons
Telemedicine
Withholding Treatment

@article {pmid41394882,
year = {2025},
author = {Padilla-Blanco, M and García-García, T and Grigas, J and López-Ayllón, BD and Garrido, JJ and Oliva, MA and Montoya, M},
title = {Hidden players of COVID-19: the evolving roles of SARS-CoV-2 accessory proteins.},
journal = {Frontiers in immunology},
volume = {16},
number = {},
pages = {1726698},
pmid = {41394882},
issn = {1664-3224},
mesh = {Humans ; *SARS-CoV-2/immunology/genetics ; *COVID-19/immunology/virology ; Host-Pathogen Interactions/immunology ; Interferon Type I/immunology/metabolism ; Animals ; *Viral Regulatory and Accessory Proteins/immunology/genetics/metabolism ; Viral Proteins/immunology ; },
abstract = {SARS-CoV-2 accessory proteins (APs), particularly ORF3a and ORF9b, have emerged as key modulators of host-pathogen interaction and potential contributors to long COVID. Of the 13 predicted APs, only nine are expressed during infection - termed Infection-related APs - while the remaining are classified as Putative APs. Despite this distinction, extensive gene overlap among APs underscores the remarkable adaptability of SARS-CoV-2 viral genome. This review delves into the diverse roles of the original Wuhan APs and their Omicron counterparts in shaping host immunity, with an emphasis on their ability to suppress type I interferon (IFN-I) signalling, modulate cellular metabolism, and trigger inflammatory/apoptotic pathways. By integrating immunopathological insights with evolutionary dynamics and structural perspectives, this review provides a comprehensive understanding of the mechanism underlying Omicron's reduced pathogenicity and highlights promising, yet unexplored, therapeutic targets within the SARS-CoV-2 accessory proteome.},
}

Humans
*SARS-CoV-2/immunology/genetics
*COVID-19/immunology/virology
Host-Pathogen Interactions/immunology
Interferon Type I/immunology/metabolism
Animals
*Viral Regulatory and Accessory Proteins/immunology/genetics/metabolism
Viral Proteins/immunology

@article {pmid41394849,
year = {2025},
author = {Gabig-Cimińska, M},
title = {Dysregulated TFEB-autophagy-lysosome pathway links acute COVID-19 immunopathology to Long COVID sequelae.},
journal = {Frontiers in immunology},
volume = {16},
number = {},
pages = {1708364},
pmid = {41394849},
issn = {1664-3224},
mesh = {Humans ; *COVID-19/immunology/pathology/complications ; *Lysosomes/immunology/metabolism ; *Basic Helix-Loop-Helix Leucine Zipper Transcription Factors/metabolism/immunology ; *Autophagy/immunology ; *SARS-CoV-2/immunology ; Animals ; Signal Transduction/immunology ; Immunity, Innate ; },
abstract = {SARS-CoV-2 disrupts cellular homeostasis, including the autophagy-lysosome pathway (ALP), a critical component of innate immunity and viral clearance. By subverting autophagy, SARS-CoV-2 proteins such as ORF3a, ORF7a, and NSP6 inhibit autophagosome-lysosome (APG-L) fusion, generating "incomplete autophagy" that permits viral persistence and drives hyperinflammation. Transcription factor EB (TFEB), a master regulator of lysosomal biogenesis and autophagy, has emerged as a central player in the host response to coronavirus infection. TFEB orchestrates the expression of genes required for lysosomal function and autophagic flux while also shaping immune processes, including cytokine production, interferon-stimulated gene expression, and inflammasome clearance. This mini review synthesizes current knowledge on the TFEB-ALP axis in COVID-19 pathogenesis, highlighting its influence on acute immunopathology and its potential contribution to post-acute sequelae (Long COVID). Restoring TFEB activity and autophagic flux may counteract SARS-CoV-2 evasion strategies and restrain aberrant inflammatory responses. Harnessing the TFEB-autophagy pathway as a host-directed therapeutic strategy could help rebalance immune homeostasis, limit tissue damage during acute infection, and mitigate persistent inflammatory sequelae in Long COVID.},
}

Humans
*COVID-19/immunology/pathology/complications
*Lysosomes/immunology/metabolism
*Basic Helix-Loop-Helix Leucine Zipper Transcription Factors/metabolism/immunology
*Autophagy/immunology
*SARS-CoV-2/immunology
Animals
Signal Transduction/immunology
Immunity, Innate

@article {pmid41392909,
year = {2025},
author = {Pandey, V and Sen, D and Rathee, S and Soni, S and Mishra, S and Jain, SK and Patil, UK},
title = {Unlocking Toll-Like Receptors: Targeting Therapeutics for Respiratory Tract Infections and Inflammatory Disorders.},
journal = {Recent advances in inflammation & allergy drug discovery},
volume = {19},
number = {3},
pages = {303-315},
doi = {10.2174/0127722708329138240926073013},
pmid = {41392909},
issn = {2772-2716},
mesh = {Humans ; *Toll-Like Receptors/immunology/metabolism/antagonists & inhibitors ; COVID-19/immunology ; *Respiratory Tract Infections/drug therapy/immunology ; *Inflammation/drug therapy/immunology ; *COVID-19 Drug Treatment ; Animals ; SARS-CoV-2 ; Signal Transduction/drug effects ; Immunity, Innate/drug effects ; },
abstract = {The Toll-like Receptors (TLRs) family has significantly enhanced the understanding of innate immune responses by identifying and responding to various microbes or host-derived organisms. TLRs contribute to these responses by increasing the levels of cytokines, interleukins, and other inflammatory mediators through multiple pathways. Located both intracellularly and on the surface of various cells and tissues, including vascular smooth muscles (VSMs) and myocardium cells, TLRs play distinct roles in innate immune activation, such as recognizing pathogen-associated molecular patterns (PAMPs) and activating downstream signaling pathways. In the context of COVID-19, TLRs are critically involved in the pathophysiology by mediating excessive inflammatory responses that exacerbate disease severity, influencing both the acute phase and long-term outcomes. It has been observed that inflammatory diseases such as atherosclerosis, viral myocarditis, and other comorbidities associated with the spread of COVID-19 have increased, although the exact mechanisms remain not fully understood. Nonetheless, there is evidence of TLR-mediated increased pro-inflammatory signaling by different mechanisms in these diseases. This review explains the role of TLRs in various inflammatory diseases related to COVID-19, including viral myocarditis, acute lung infections, and atherosclerosis. Furthermore, the review discusses various herbal drugs, such as Platycodon grandiflorum, Acanthopanax senticosus, Scutellaria baicalensis Georgi, and Engelhardia roxburghiana, and their mechanisms of action on TLRs, including NF-κB, MyD88-dependent, MyD88-independent pathways, and Plasmacytoid DCs. Enhanced clarity on TLRs' specific contributions to COVID-19 pathophysiology and stronger evidence supporting herbal interventions targeting TLRs could improve the impact and applicability of these findings in clinical settings.},
}

Humans
*Toll-Like Receptors/immunology/metabolism/antagonists & inhibitors
COVID-19/immunology
*Respiratory Tract Infections/drug therapy/immunology
*Inflammation/drug therapy/immunology
*COVID-19 Drug Treatment
Animals
SARS-CoV-2
Signal Transduction/drug effects
Immunity, Innate/drug effects

@article {pmid41392882,
year = {2025},
author = {de Bruin, O and Maisonneuve, E and Hurley, E and Nordeng, HME and Bérard, A and Sheehy, O and Kaul, P and Shinde, MU and Cosgrove, A and Lyons, JG and Messenger-Jones, E and Kempner, ME and Toh, S and Hua, W and Hernández-Muñoz, JJ and Sahin, L and Cesta, CE and Hägg, D and Gini, R and Paoletti, O and Poblador-Plou, B and Jordan, S and Rodríguez-Bernal, CL and Sánchez-Sáez, F and Lassalle, R and Bernard, MA and Ahmadizar, F and Favre, G and Panchaud, A and Bloemenkamp, KWM and Plueschke, K and de Vries, C and Siiskonen, SJ and Sturkenboom, MCJM and , },
title = {Adverse outcomes among pregnant women with COVID-19 according to hospitalization status: A prospective individual participant data meta-analysis in Europe and North America.},
journal = {International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics},
volume = {},
number = {},
pages = {},
doi = {10.1002/ijgo.70694},
pmid = {41392882},
issn = {1879-3479},
support = {//European Medicines Agency/ ; /CAPMC/CIHR/Canada ; //Canada Foundation for Innovation/ ; /FD/FDA HHS/United States ; },
abstract = {BACKGROUND: Understanding the varied impact of COVID-19 severity on pregnancy outcomes is crucial for informed clinical management and targeted interventions.

OBJECTIVE: To evaluate the impact of COVID-19 on pregnancy outcomes, distinguishing between pregnant women managed in primary care and those requiring hospitalization.

SEARCH STRATEGY: Regulatory authorities actively promoted global cooperation on COVID-19's impact during pregnancy. Data were obtained through these regulatory bodies and direct researcher communication rather than through systematic searches.

SELECTION CRITERIA: Data sources required secondary population-based data to identify pregnancies with COVID-19, along with hospitalization, diagnostic and medication codes. Eligibility for the meta-analysis was determined through protocol evaluation and researcher consultations.

DATA COLLECTION AND ANALYSIS: PRISMA-IPD and Cochrane guidelines for prospective meta-analysis were followed. Protocols and definitions were standardized across sources, and a common R script was developed. Initially, crude and adjusted relative risks (aRR) with 95% confidence intervals (CI) were calculated to assess adverse outcomes in pregnant women with and without COVID-19 in each data source. Estimates were stratified by trimester at infection and hospitalization status. Subsequently, data were pooled using a random-effects meta-analysis.

MAIN RESULTS: Data from 10 sources across seven countries contributed to the meta-analysis, including 86 210 pregnant women diagnosed with COVID-19, of whom 4.4% were hospitalized. Non-hospitalized pregnant women with COVID-19 had no increased risks of adverse outcomes compared to pregnant women without COVID-19. However, hospitalized women with COVID-19 in each trimester had higher risks of cesarean section, preterm birth, and LBW compared to pregnant women without COVID-19. Hospitalization due to COVID-19 in the third trimester was associated with increased risk of stillbirth (aRR 5.90, 95% CI: 2.22-15.71, I[2] = 0%). First-trimester hospitalizations due to COVID-19 did not show heightened risks of GDM (aRR 2.08, 95% CI: 0.93-4.64, I[2] = 65%), pre-eclampsia (aRR 1.79, 95% CI: 0.48-6.66, I[2] = 71%), or major congenital anomalies (aRR 1.30, 95% CI: 0.55-3.06, I[2] = 0%).

CONCLUSIONS AND RELEVANCE: COVID-19 requiring hospitalization is associated with adverse pregnancy outcomes, emphasizing the need to prevent severe illness during pregnancy. This study also highlights the importance of international collaboration for gathering pregnancy data and shows that building global research networks is essential for responding to future health crises.},
}

@article {pmid41392436,
year = {2025},
author = {Celano, R and Urso, F and Bartoli, A and Meschia, A and Masseroli, MM and Cirigliano, F and Colaneri, M and Foschi, A and Gori, A and Cogliati, C and Calloni, M and Taino, A and Scoppettuolo, G and Pittiruti, M and Gidaro, A},
title = {COVID-19 and vascular access: Evidence and lessons for improving the standard of care, a scoping review.},
journal = {The journal of vascular access},
volume = {},
number = {},
pages = {11297298251398421},
doi = {10.1177/11297298251398421},
pmid = {41392436},
issn = {1724-6032},
abstract = {The Coronavirus Disease 2019 (COVID-19) pandemic has significantly impacted intravenous therapy practices, particularly in critically ill patients. Vascular access strategies were adapted to evolving clinical needs, infection control priorities, and resource limitations, with a focus on safety, efficacy, and technological advancements. This scoping review aimed to explore how the COVID-19 pandemic affected vascular access practices and catheter-related complications, with the objective of mapping innovations, identifying emerging trends, and summarizing preventive and therapeutic strategies. The review followed PRISMA-ScR guidelines and was registered in PROSPERO (CRD420251027530). A systematic search was conducted in PubMed[®], EMBASE[®], EBSCO-CINAHL[®], and CENTRAL for English-language studies published between January 2020 and May 2025 addressing catheter-related complications in COVID-19 patients, including catheter-related bloodstream infections (CRBSI), central line-associated bloodstream infections (CLABSI), catheter-related thrombosis (CRT), and accidental catheter removal. Among 521 screened articles, 58 met the inclusion criteria. Most studies reported higher rates of CRBSI, CLABSI, CRT, and accidental removal in COVID-19 patients, especially in critical care settings. Arterial catheters were also associated with elevated risks of thrombosis and infection during the pandemic. Mid-thigh femoral access sites emerged as practical alternatives to reduce central line use and healthcare personnel exposure. Technological advances, including power-injectable catheters, ultrasound-guided insertion, intracavitary ECG for tip confirmation, and securement tools such as cyanoacrylate glue and subcutaneous anchor systems, improved safety and reduced mechanical and infectious complications. Chlorhexidine-based antisepsis, antimicrobial-impregnated devices, and disinfectant caps effectively decreased CRBSI and CLABSI rates. In older, comorbid patients-now representing the majority of COVID-19 hospitalizations-nutritional and anticoagulant therapy must be carefully balanced to minimize bleeding and thrombotic risks. In conclusion, the pandemic catalyzed significant innovation and adaptation in vascular access practices. Integrating portable technologies, infection prevention strategies, and alternative access routes has enhanced patient care and established new standards for managing intravenous therapy in high-risk, resource-constrained settings.},
}

@article {pmid41391467,
year = {2025},
author = {Rutter, H and Wabnitz, K and Nambiar, D and Garde, A and Benton, TG and Heymann, DL and Yates, R and Friel, S and Hollands, GJ and Cai, W and Chater, N and Bloom, DE and Guinto, RR and El Omrani, O and Wilsdon, J and Amuasi, JH and Butler, C and Tlou, S and Marteau, TM},
title = {The Lancet Commission on improving population health post-COVID-19.},
journal = {Lancet (London, England)},
volume = {},
number = {},
pages = {},
doi = {10.1016/S0140-6736(25)02061-6},
pmid = {41391467},
issn = {1474-547X},
}

@article {pmid41390653,
year = {2025},
author = {Waqqas, HM and Pan, J and Xia, N and Chen, W},
title = {mRNA based vaccines and therapeutics for parasitic infections: a comprehensive review.},
journal = {Journal of nanobiotechnology},
volume = {},
number = {},
pages = {},
doi = {10.1186/s12951-025-03787-z},
pmid = {41390653},
issn = {1477-3155},
support = {SKLRD-OP-202409//Open Project of the State Key Laboratory of Respiratory Disease/ ; },
abstract = {The success of mRNA vaccines during the COVID-19 pandemic has revealed a revolutionary platform for addressing neglected parasite zoonosis, which represent a continual and significant threat to world health, especially in resource-constrained settings. The current review consolidates recent progress in the development of mRNA-based treatments, vaccines, and diagnostic ways for these pathogens. We elucidate how customized delivery platforms, particularly lipid nanoparticles, augment the stability and immunogenicity of parasite-derived mRNA cargo by safeguarding it from degradation and promoting uptake by antigen-presenting cells. Our findings suggest that mRNA technology provides a particularly adaptable strategy to targeting complicated parasite life cycles and efficiently modulating host immune responses. However, important challenges, such as cold-chain logistics, scalability, clinical trial design for diverse populations, and managing public opinion, must be solved beforehand. Future initiatives must priorities the creation of thermostable formulations and effective community participation strategies. Finally, this review emphasizes that mRNA-based interventions represent a promising, albeit challenging, frontier in the fight against parasitic diseases, urging a collaborative cross-disciplinary effort to translate this potential into tangible health breakthroughs for the world's most vulnerable populations.},
}

@article {pmid41297153,
year = {2025},
author = {Kattner, AA},
title = {Sticks and stones - mending bones.},
journal = {Biomedical journal},
volume = {48},
number = {6},
pages = {100931},
pmid = {41297153},
issn = {2320-2890},
mesh = {Humans ; *COVID-19/prevention & control ; *Bone Regeneration ; COVID-19 Vaccines ; SARS-CoV-2 ; },
abstract = {A novel biomaterial demonstrates enhanced bone regeneration in critical defects, offering potential improvements in orthopedic repair. In immunology, a second booster dose of mRNA COVID-19 vaccine is shown to elicit robust responses in older adults in Taiwan. Hepatology research explores new therapeutic strategies for managing hepatitis B in kidney transplant recipients. Biomarker discovery advances with a new assay enabling the use of miRNAs for non-invasive diagnosis and staging of metabolic dysfunction-associated steatotic liver disease (MASLD). Finally, an optimized elastase assay improves FISH-based detection of ALK gene rearrangements, enhancing diagnostic accuracy in non-small cell lung cancer (NSCLC).},
}

Humans
*COVID-19/prevention & control
*Bone Regeneration
COVID-19 Vaccines
SARS-CoV-2

@article {pmid40608563,
year = {2026},
author = {Bernstein, WK and Pearl, RG and Huang, J and Mayrsohn, BG and Mery, MW and Banoub, M and Pease, S and Ayad, S and Saffary, R and Olszewski, RF and Aronson, S and Vetter, TR},
title = {Enhancing Anesthetic Preoptimization: Promising Opportunities for Innovation in Economically Diverse Regions.},
journal = {Anesthesia and analgesia},
volume = {142},
number = {1},
pages = {76-84},
pmid = {40608563},
issn = {1526-7598},
mesh = {Humans ; *COVID-19/economics/epidemiology ; *Perioperative Care/economics/methods ; *Anesthesia/economics/methods ; *Preoperative Care/economics/methods/trends ; Anesthesiologists/economics ; },
abstract = {The escalating costs of perioperative care are unsustainable, necessitating the identification of high-impact investment opportunities to enhance both quality and cost-effectiveness of perioperative processes. In both rural and urban areas with less access to health care resources, a sustainable health care system must focus on delivering value-based care and prioritizing population health, promoting efficiency, preventing complications, and optimizing outcomes. Given the shortage of primary care physicians, and the lessons learned from the COVID-19 pandemic, which emphasized the importance of a systems-based approach, as well as the evolving roles in the perioperative surgical home and ERAS pathways, anesthesiologists are in a prime position to contribute to these essential value-based objectives. They can achieve this by playing a more active role in the preoperative evaluation and optimization of patients.This paper presents a comprehensive review of pertinent perioperative medical conditions (obstructive sleep apnea, hypertension, anemia, food insecurity and nutrition, diabetes, cognitive and brain health) that can be optimized before surgery. It highlights the latest research and innovations in preoperative management that can significantly alter intraoperative anesthetic management of these conditions leading to reduced morbidity and mortality among surgical patients. Furthermore, this paper highlights existing gaps in preoperative management, particularly in the optimization of comorbid medical conditions.},
}

Humans
*COVID-19/economics/epidemiology
*Perioperative Care/economics/methods
*Anesthesia/economics/methods
*Preoperative Care/economics/methods/trends
Anesthesiologists/economics

@article {pmid41387929,
year = {2025},
author = {Kanno, H and Liu, Z and Sato, R and Endo, H and Niizuma, K and Goda, K},
title = {Single-pixel imaging flow cytometry for biomedical research.},
journal = {Inflammation and regeneration},
volume = {45},
number = {1},
pages = {36},
pmid = {41387929},
issn = {1880-9693},
abstract = {High-throughput single-cell analysis and screening have become essential tools in life science research. Imaging flow cytometry, in particular, enables large-scale image-based profiling of heterogeneous cell populations, allowing statistical analysis of cellular morphology, subcellular features, and functional responses. However, its analytical capability is often limited by the use of conventional two-dimensional (2D) image sensors. In this review, we highlight recent advances in single-pixel imaging flow cytometry, which replaces 2D image sensors with single-pixel photodetectors. This approach offers advantages in sensitivity, flexibility, and speed in imaging system design and has been implemented in various optical configurations to achieve high-throughput single-cell imaging. We first introduce its key techniques, then outline representative biomedical applications, including cancer and COVID-19 research, and finally discuss current limitations and prospects for future developments. Single-pixel imaging flow cytometry is expected to serve as a versatile platform supporting both basic and translational studies in diverse biomedical applications.},
}

@article {pmid41366793,
year = {2025},
author = {Chen, H and Zhang, J and Huang, J and Wu, Z and Tang, L and Tian, Y and Gao, S and Huang, S and Cao, J and Chen, J and Li, Y},
title = {Convergence of mRNA technology and chimeric antigen receptor therapy: targeted technology optimizing targeted therapy.},
journal = {Journal of translational medicine},
volume = {23},
number = {1},
pages = {1393},
pmid = {41366793},
issn = {1479-5876},
abstract = {Engineering cells to express chimeric antigen receptors (CARs) represents a novel approach in cancer immunotherapy, demonstrating remarkable efficacy in the treatment of hematologic malignancies while also encountering numerous challenges. Against the backdrop of the widespread application of COVID-19 mRNA vaccines, the integration of mRNA technology to produce CAR cells and enhance CAR therapies marks the cutting edge of cancer treatment innovation, offering potential solutions to the challenges faced by traditional CAR therapies. This convergence offers distinct advantages. It enables the generation of CAR cells both in vitro and in vivo without transgene integration, thereby achieving transient expression that reduces the risk of various side effects. Meanwhile, this approach entails lower production costs. This method may therefore serve as a novel and promising alternative to existing therapies in the future. In this article, we review the latest advancements and clinical applications of mRNA-based CAR therapies, which utilize mRNA technology to generate CAR-T cells. Additionally, we explore the diverse therapies enabled by mRNA technology, such as gene editing and vaccines, and their combination with CAR therapies. By analyzing their challenges and prospects, we aim to provide new insights into comprehensively improving the therapeutic efficacy of CAR therapies and expanding their clinical application.},
}

@article {pmid40292916,
year = {2025},
author = {Barton, MJ and Okada, M and Todorovic, M},
title = {Podcasts in health education-Insights from a scoping review and survey.},
journal = {Anatomical sciences education},
volume = {18},
number = {12},
pages = {1388-1405},
doi = {10.1002/ase.70037},
pmid = {40292916},
issn = {1935-9780},
mesh = {Humans ; *Webcasts as Topic ; *Health Education/methods ; Surveys and Questionnaires ; *COVID-19/epidemiology ; Adult ; Male ; Female ; },
abstract = {Podcasts have rapidly emerged as a powerful tool for health communication, especially since the COVID-19 pandemic. While evidence shows that podcasts can enhance student knowledge, confidence, and flexibility in learning, their educational impact is primarily studied within formal academic contexts. Despite their popularity and potential, little is known about how bioscience-focused health podcasts engage broader audiences beyond structured health education programs. Limited research examines who listens, why they choose podcasts, and how this format influences their learning or behavior. To address this, we used a mixed-methods approach comprising a scoping review and an exploratory online survey. The scoping review, following PRISMA guidelines, identified 14 eligible studies published between 2008 and 2024. The survey, distributed via social media and Dr. Matt & Dr. Mike's Medical Education Podcast, captured responses from 226 participants-predominantly aged 25-34 and mostly from the USA-with two-thirds enrolled in health programs. Participants cited access to expert insights, enjoyment, and the ability to multitask as key reasons for podcast use. Content relevance and presenter expertise were rated the most important factors when selecting a health podcast. The preferred episode length was 30-60 min. On average, participants rated the impact of podcasts on their health knowledge at 4.22 out of 5, with 58% reporting changes in health-related behaviors. These findings suggest that podcasts offer a flexible, engaging way to communicate bioscience-focused health content and support learning across diverse audiences. Educators should consider listener motivations and preferences when integrating podcasts into educational practice.},
}

Humans
*Webcasts as Topic
*Health Education/methods
Surveys and Questionnaires
*COVID-19/epidemiology
Adult
Male
Female

@article {pmid41386922,
year = {2025},
author = {Bhalla, A and Tummalapalli, SL and Silberzweig, J},
title = {Quality Metrics in Dialysis: It Takes a Village.},
journal = {Advances in kidney disease and health},
volume = {32},
number = {5},
pages = {451-459},
doi = {10.1053/j.akdh.2024.12.001},
pmid = {41386922},
issn = {2949-8139},
mesh = {Humans ; *COVID-19/epidemiology ; *Renal Dialysis/standards ; *Kidney Failure, Chronic/therapy ; United States ; *Patient Care Team/organization & administration ; SARS-CoV-2 ; *Quality of Health Care ; Hemodialysis, Home/standards ; },
abstract = {Dialysis is a specialized therapy rendered by a team of interdisciplinary professionals. Federal regulations mandate that dialysis facility staff, at minimum, include a registered nurse, physician, social worker, and dietitian. To ensure that patients on dialysis receive high-quality care, the Centers for Medicare and Medicaid Services introduced the first federally mandated pay for performance program in January 2012: the ESRD Quality Incentive Program. Quality metrics in the ESRD Quality Incentive Program have continuously evolved, necessitating greater involvement from the dialysis interdisciplinary team. In this article, we discuss the interdisciplinary nature of dialysis facility staffing and highlight the critical role of all care team members in attaining high performance on dialysis quality metrics. In the context of the coronavirus disease 2019 pandemic, we highlight recent staffing challenges and propose strategies to alleviate workforce shortages. Finally, we review 2 major trends: (1) an increased emphasis on home dialysis and (2) calls to address social determinants of health, which will require the interdisciplinary team to assume an even larger role in achieving high-quality care.},
}

Humans
*COVID-19/epidemiology
*Renal Dialysis/standards
*Kidney Failure, Chronic/therapy
United States
*Patient Care Team/organization & administration
SARS-CoV-2
*Quality of Health Care
Hemodialysis, Home/standards

@article {pmid41046954,
year = {2025},
author = {Welc, N and Anioła, A and Ważniewicz, S and Michalak, M and Jałowska, M and Dańczak-Pazdrowska, A and Grzybowski, A and Żaba, R and Kavanagh, K},
title = {Syphilis incidence during the COVID-19 pandemic: systematic review and meta-analysis.},
journal = {Clinics in dermatology},
volume = {43},
number = {6},
pages = {836-849},
doi = {10.1016/j.clindermatol.2025.09.031},
pmid = {41046954},
issn = {1879-1131},
mesh = {Humans ; *Syphilis/epidemiology/diagnosis/transmission ; *COVID-19/epidemiology ; Incidence ; Pandemics ; SARS-CoV-2 ; Health Services Accessibility ; },
abstract = {The COVID-19 pandemic created a public health crisis that affected mental and physical health. Research examined its effect on sexually transmitted infections, particularly syphilis. Asymptomatic stages and inadequate screening likely delayed detection and increased transmission after restrictions eased. Limited health care access and lockdowns reduced social interactions. Studying syphilis reveals how changes in health care access influenced transmission, showcasing the pandemic as a natural experiment for sexually transmitted infection epidemiology. We used the PubMed database, selecting studies from 2019 to August 2024. The meta-analysis evaluated incidence rate ratios from 2019 to 2020 to assess the pandemic's global impact on syphilis rates. Published papers were categorized by region for subgroup analysis. Of the 233 studies, 21 were selected for further analysis. A common-effects model was used to calculate the incidence rate ratio with a 95% CI. We assessed publication bias using funnel plot asymmetry and Egger test, examining heterogeneity with the I[2] statistic. We found a 14% decrease in syphilis incidence in various regions (incidence rate ratio: 1.14; 95% CI: 1.06-1.24, P = .006). Analysis by country and city was inconclusive. This indicates that the impact of the epidemic on syphilis transmission and diagnosis may be multifactorial. Syphilis incidence fell during the pandemic, illustrating that reduced health care access and social restrictions affected transmission. National analyses were inconclusive, suggesting the pandemic's effects on syphilis may vary by location. These findings emphasize the need for further research on the pandemic's long-term impact on syphilis trends and the importance of improving sexually transmitted infection surveillance and health care access during recovery.},
}

Humans
*Syphilis/epidemiology/diagnosis/transmission
*COVID-19/epidemiology
Incidence
Pandemics
SARS-CoV-2
Health Services Accessibility

@article {pmid41386679,
year = {2025},
author = {Hamel, LP},
title = {Nicotiana benthamiana's Responses to Agroinfiltration, a Treasure Grove of New Avenues to Improve Protein Yields in Plant Molecular Farming.},
journal = {Plant biotechnology journal},
volume = {},
number = {},
pages = {},
doi = {10.1111/pbi.70460},
pmid = {41386679},
issn = {1467-7652},
abstract = {Transient expression of recombinant proteins in leaves of Nicotiana benthamiana is routinely employed for both basic research and manufacturing of biopharmaceutical products in plants. Relying on disarmed strains of the bacterial plant pathogen Agrobacterium tumefaciens as a transgene vector, this safe, cost-effective and easily scalable 'plant molecular farming' approach offers a reliable alternative to classical protein expression platforms. Commonly referred to as agroinfiltration, scaled-up versions of this manufacturing process have now become helpful in the fight against global health issues, such as those rapidly evolving virus strains causing influenza or coronavirus disease 2019. In the past decades, considerable efforts have been deployed to improve the efficacy of Agrobacterium-mediated expression, including through the development of new binary vectors, the design of strong promoters, and the deployment of approaches to increase levels and stability of transgene mRNAs. By comparison, much less attention has been given to understanding the effects that agroinfiltration unavoidably has on host plants, including the infiltration process itself, the perception of Agrobacterium and the subsequent accumulation of recombinant products throughout the expression phase. Using the upregulation profiles of plant receptor genes during the heterologous expression of virus-like particles in N. benthamiana leaves, I here describe how some of these host responses interact with each other to form an intricate signalling interplay at the molecular level. I also review host plant's responses to agroinfiltration and highlight strategies that have emerged to improve the efficacy of plant cell biofactories based on the better understanding of this transient expression system.},
}

@article {pmid41385537,
year = {2025},
author = {Takkar, A and Mahesh, KV and Shree, R and Tigari, B and Chatterjee, D and Ahuja, CK and Lal, V},
title = {Neuro-ophthalmology of Infectious Diseases.},
journal = {Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society},
volume = {45},
number = {3},
pages = {362-377},
pmid = {41385537},
issn = {1536-5166},
mesh = {Humans ; *Ophthalmology/methods ; *Eye Infections/diagnosis ; *Neurology ; },
abstract = {BACKGROUND: According to the World Health Organization, infections, particularly sepsis, are linked to over 20% mortality worldwide and are leading cause of morbidity. A variety of infections have neuro-ophthalmic manifestations. The profile of infectious agents, clinical manifestations, severity, and prognosis of these diseases are highly heterogeneous, and it is therefore difficult to make generalized statements about management.

EVIDENCE ACQUISITION: Available literature with regard to individual infectious agents and their neuroophthalmic manifestations or complications was searched using electronic databases such as PubMed, MEDLINE, Scopus, ProQuest, and Embase. The current study is a review of the literature along with the authors' personal experience in this field.

RESULTS: In this review, we describe the key neuro-ophthalmic manifestations of common bacterial, fungal, viral (except HIV, opportunistic infections, and COVID-19 virus), parasitic, and protozoal infections using illustrative examples.

CONCLUSIONS: Infections may involve the afferent and efferent visual pathways, as well as higher order visual processing functions. They can directly invade the eye and the brain or may cause damage due to inflammation, necrosis, vascular compromise, and postinfective demyelination. With the shifting geographic boundaries and widespread international migration, the spectrum of infectious neuro-ophthalmic diseases is expanding. Clinical details, dedicated imaging, biochemical, serological, and at times histopathological confirmation aids in making prompt diagnosis.},
}

Humans
*Ophthalmology/methods
*Eye Infections/diagnosis
*Neurology

@article {pmid41385334,
year = {2025},
author = {Yang, Y and Sun, Y and Kang, X and Wang, Y},
title = {mRNA vaccine platforms and novel delivery systems: From mechanistic principles to clinical translation.},
journal = {Human vaccines & immunotherapeutics},
volume = {21},
number = {1},
pages = {2597629},
doi = {10.1080/21645515.2025.2597629},
pmid = {41385334},
issn = {2164-554X},
mesh = {Humans ; *COVID-19 Vaccines/immunology/administration & dosage ; *Drug Delivery Systems/methods ; *Vaccines, Synthetic/immunology/administration & dosage ; *COVID-19/prevention & control/immunology ; Nanoparticles ; Vaccine Development ; *RNA, Messenger/immunology/administration & dosage/genetics ; *mRNA Vaccines/immunology/administration & dosage ; SARS-CoV-2/immunology ; Vaccines, Virus-Like Particle/administration & dosage/immunology ; },
abstract = {Messenger RNA (mRNA) vaccines have revolutionized the field of vaccinology, offering rapid design flexibility, scalable manufacturing, and strong immunogenicity. The unprecedented success of COVID-19 mRNA vaccines has accelerated research into novel delivery platforms and expanded therapeutic applications beyond infectious diseases to cancer immunotherapy and immune-mediated disorders. This review provides a comprehensive overview of the mechanistic principles underlying mRNA vaccine design, including mRNA engineering strategies, delivery innovations such as lipid nanoparticles (LNPs), polymeric nanoparticles (PNPs), and virus-like particles (VLPs), as well as emerging needle-free administration technologies. We further highlight recent advances in therapeutic areas spanning infectious diseases (e.g. HIV, tuberculosis, respiratory syncytial virus), oncology, and non-traditional indications such as autoimmune disorders. Despite remarkable progress, critical challenges persist in vaccine stability, delivery efficiency, large-scale manufacturing, and global accessibility. Finally, we discuss future research directions integrating artificial intelligence, nanotechnology, and systems immunology to accelerate next-generation mRNA vaccine development and clinical translation.},
}

Humans
*COVID-19 Vaccines/immunology/administration & dosage
*Drug Delivery Systems/methods
*Vaccines, Synthetic/immunology/administration & dosage
*COVID-19/prevention & control/immunology
Nanoparticles
Vaccine Development
*RNA, Messenger/immunology/administration & dosage/genetics
*mRNA Vaccines/immunology/administration & dosage
SARS-CoV-2/immunology
Vaccines, Virus-Like Particle/administration & dosage/immunology

@article {pmid41384659,
year = {2025},
author = {Bessalah, S and Sinha, D and Yuan, X and Paul, S and Longet, S},
title = {[Long COVID: therapeutic challenges and opportunities in the face of persistent sequelae].},
journal = {Medecine sciences : M/S},
volume = {41},
number = {11},
pages = {869-876},
doi = {10.1051/medsci/2025185},
pmid = {41384659},
issn = {1958-5381},
mesh = {Humans ; *COVID-19/complications/therapy/epidemiology ; *SARS-CoV-2/physiology ; Post-Acute COVID-19 Syndrome ; Pandemics ; COVID-19 Drug Treatment ; Antiviral Agents/therapeutic use ; Chronic Disease ; },
abstract = {The COVID-19 pandemic, caused by SARS-CoV-2, has not only led to a global health and economic crisis but also renewed attention to a clinical phenomenon of persistent symptoms after viral infection. This phenomenon is defined as long COVID or post-COVID-19 syndrome. Approximately one in eight patients experience persistent symptoms of varying intensity after the acute phase of the infection. This phenomenon, combined with the virus's high transmissibility and rapid mutation rate, poses a major public health challenge. This review examines various therapeutic approaches currently under consideration for treating long COVID, and explores future prospects in this field.},
}

Humans
*COVID-19/complications/therapy/epidemiology
*SARS-CoV-2/physiology
Post-Acute COVID-19 Syndrome
Pandemics
COVID-19 Drug Treatment
Antiviral Agents/therapeutic use
Chronic Disease

@article {pmid41384439,
year = {2025},
author = {Van Houtte, P and Lamarche, F and Every-Palmer, S},
title = {Effects of face coverings on people and interactions in mental health settings: scoping review.},
journal = {BJPsych open},
volume = {12},
number = {1},
pages = {e11},
doi = {10.1192/bjo.2025.10917},
pmid = {41384439},
issn = {2056-4724},
abstract = {BACKGROUND: Early in the SARS-CoV-2 pandemic, most jurisdictions implemented mandatory face covering policies across healthcare settings. This intervention, which lasted multiple years, was unprecedented in psychiatry. Masks may affect the delivery of mental healthcare, given its reliance on nuanced communication and establishing a therapeutic alliance.

AIMS: This scoping review aimed to provide an overview of the current literature concerning the impact of face masks in mental health settings beyond infection control and identify research gaps to guide future research and policy.

METHOD: Systematic searches were completed in the MEDLINE, Embase, PsycINFO, Scopus and CINAHL databases on 14 August 2024. Articles were eligible if they described peer-reviewed empirical studies involving people with mental disorders or mental health clinicians that reported on impacts of face coverings.

RESULTS: Twenty-eight studies were selected for inclusion, involving 5385 participants. There was considerable heterogeneity among studies. Negative effects of face masks were reported in 26 studies in at least one domain. Themes from the survey-based literature included face masks negatively affecting communication, the therapeutic relationship and overall assessment quality. Experimental studies using emotion recognition tasks showed that people with mental disorders were disadvantaged by masks when interpreting emotions from facial expressions. The most commonly studied population was people with autism spectrum disorder. Children and people with severe or acute mental illness were underrepresented. Only two studies expressly recruited psychiatrists.

CONCLUSIONS: Policy makers should be aware of adverse impacts of mask-wearing in mental health settings and consider these in evolving risk-benefit analyses. Further research is needed to establish the extent of impacts on population subgroups.},
}

@article {pmid41383825,
year = {2025},
author = {Trulik, KG and Kumar, VA and Wu, W and Varma, M and Patel, MM and Manglani, K and Mathew, TA},
title = {Exploring Stress, Fatigue, Burnout, and Resilience Among Healthcare Personnel in Southern and South-Eastern Asia: A Scoping Review.},
journal = {Public health reviews},
volume = {46},
number = {},
pages = {1608603},
pmid = {41383825},
issn = {0301-0422},
abstract = {OBJECTIVES: This study aims to compare methods used to measure burnout, fatigue, stress, and resilience, as well as resilience-building interventions among healthcare personnel (HCP) in Southern and South-eastern Asia. Even before COVID-19, HCP faced high levels of burnout and stress, exacerbated by the pandemic. Identifying effective resilience-building strategies is essential to supporting a healthier workforce.

METHODS: Studies published from January 2016 to December 2021 focusing on burnout, stress, fatigue, and resilience were included. COVIDENCE software was used for screening.

RESULTS: A total of 55 studies were included in the review. Of these 55 studies, 51 measured burnout, stress, fatigue, or resilience, using 77 different instruments. The MBI-HSS, PSS-10, BRS, Brief-COPE, and CD-RISC were the most common tools to assess burnout, stress, and individual resilience. Four studies evaluated resilience interventions, using mindfulness training, meditation, progressive muscle relaxation, and yoga.

CONCLUSION: There are many studies assessing burnout, stress, and resilience among HCP in Southern and South-eastern Asia, yet gaps remain in identifying effective resilience-building interventions. Further research is needed to assess the impact of individual resilience on health systems resilience.},
}

@article {pmid41383811,
year = {2025},
author = {Manivannan, SN and Diaz Arenas, C and Grubaugh, ND and Ogbunugafor, CB},
title = {The importance of epistasis in the evolution of viral pathogens.},
journal = {Virus evolution},
volume = {11},
number = {1},
pages = {veaf091},
pmid = {41383811},
issn = {2057-1577},
abstract = {Understanding the genetic and genomic underpinnings of infectious disease outbreaks has emerged as a frontier of epidemiology. Here, we argue that epistasis-where the phenotypic effects of mutations or gene variants are dictated by the presence of other mutations or genes-should become a focus of genomic epidemiology. To demonstrate this, we present the results of a systematic review of the literature on epistasis in viruses, focusing on three major human viral systems: (i) influenza, (ii) SARS-CoV-2, and (iii) human immunodeficiency virus, as well as two other bodies of the literature mainly focusing on nonhuman viruses: (iv) tobacco etch virus and (v) experimental evolution of viruses. Our systematic review of these five bodies of the literature highlights that epistasis is prevalent in host-virus systems of various kinds, manifesting within and between different loci, with effects of different magnitudes and directions, and shaping various phenotypic traits of epidemiological interest. At the same time, our systematic review demonstrates that our ability to draw general conclusions about the direction and magnitude of epistasis in viral evolution is constrained by several factors: the idiosyncrasies of virus-host systems, biases in the underlying data collection exercises, and the limitations of existing methods. Moving forward, we encourage collaborations between genomic epidemiologists and evolutionary biologists to identify and measure epistasis in studying the evolution of viral pathogens.},
}

@article {pmid41383618,
year = {2025},
author = {Xu, T and Zhang, J and Hou, X and Xie, X and Qi, J and Wang, C and Yan, Y and Kuang, L and Zhu, B},
title = {MIS-C pathogenesis: immune dysregulation & viral triggers.},
journal = {Frontiers in immunology},
volume = {16},
number = {},
pages = {1624963},
pmid = {41383618},
issn = {1664-3224},
mesh = {Humans ; *COVID-19/immunology/complications ; *SARS-CoV-2/immunology ; *Systemic Inflammatory Response Syndrome/immunology/therapy/etiology/virology ; Child ; Immunity, Innate ; Adaptive Immunity ; Cytokine Release Syndrome/immunology ; },
abstract = {Multisystem Inflammatory Syndrome in Children (MIS-C) is a serious condition emerging during the COVID-19 pandemic, strongly associated with prior SARS-CoV-2 infection. Characterized by systemic inflammation affecting multiple organs, MIS-C presents a complex clinical picture including fever, gastrointestinal distress, cardiac dysfunction, and neurological manifestations. Although its exact pathogenesis remains incompletely understood, immune dysregulation is recognized as a central mechanism. This review examines current understanding of MIS-C pathogenesis, focusing on immune dysfunction and viral triggers, particularly SARS-CoV-2. We analyze both innate and adaptive immune responses, cytokine storm dynamics, molecular mimicry, and virus-induced inflammatory cascades. Additionally, we discuss potential immunomodulatory therapeutic strategies and identify future research directions to improve MIS-C management and treatment outcomes.},
}

Humans
*COVID-19/immunology/complications
*SARS-CoV-2/immunology
*Systemic Inflammatory Response Syndrome/immunology/therapy/etiology/virology
Child
Immunity, Innate
Adaptive Immunity
Cytokine Release Syndrome/immunology

@article {pmid41383331,
year = {2025},
author = {Okon, MB and Ugwu, OP and Ugwu, CN and Ogenyi, FC and Swase, DT and Anyanwu, CN and Eze, VHU and Ugwu, JN and Akinola, SA and Mujinya, R and Anyanwu, EG},
title = {From pandemics to preparedness: harnessing AI, CRISPR, and synthetic biology to counter biosecurity threats.},
journal = {Frontiers in public health},
volume = {13},
number = {},
pages = {1711344},
pmid = {41383331},
issn = {2296-2565},
mesh = {Humans ; *Artificial Intelligence ; *Pandemics/prevention & control ; *Synthetic Biology ; *Biosecurity ; *Bioterrorism/prevention & control ; COVID-19/prevention & control ; *Civil Defense/methods ; Global Health ; },
abstract = {Biosecurity threats, which include natural outbreaks, laboratory accidents, and intentional bioterrorism, are a major issue for global health security. The impact of poor preparedness on the health, social, and economic effects of the 1918 influenza pandemic, the 2001 anthrax attacks, and the COVID-19 crisis is devastating. Standard methods, such as quarantine and serology, as well as traditional inoculations, offered basic defences but were often reactive, slow, and unfair. The recent scientific and technological progress has altered the concept of biosecurity preparedness by providing new instruments of early detection, quick reaction, and fair health solutions. Artificial intelligence-based epidemic prediction, next-generation sequencing, CRISPR-based diagnostics, and digital epidemiology are emerging technologies that enable near-real-time surveillance. New therapeutic agents and vaccines, such as mRNA and DNA platforms, monoclonal antibodies, and nanobody therapies, have enhanced response capabilities. Containment measures based on robotics, biosensors, nanotechnology-based PPE, and portable biocontainment units have simultaneously improved frontline safety. Sensitive health information and enhanced coordination are today secured with the help of digital and cyber-biosecurity tools. Nonetheless, the innovations have ethical, legal, and equity issues, which point to the need to govern responsibly and make them accessible to all. This review brings forth the incorporation of emerging technologies with international cooperation, fair systems, and responsive policies as the keys to developing resilient and future-orientated systems that could help alleviate natural, accidental, and intentional biosecurity threats.},
}

Humans
*Artificial Intelligence
*Pandemics/prevention & control
*Synthetic Biology
*Biosecurity
*Bioterrorism/prevention & control
COVID-19/prevention & control
*Civil Defense/methods
Global Health

@article {pmid41380396,
year = {2025},
author = {Ballout, S and Darwish, SA and Kelly, PJ and Keller, T and Shegog, R and Aboul-Enein, BH},
title = {The use of storytelling in COVID-19 vaccine promotion: A scoping review of interventions and campaigns.},
journal = {Vaccine},
volume = {72},
number = {},
pages = {128098},
doi = {10.1016/j.vaccine.2025.128098},
pmid = {41380396},
issn = {1873-2518},
abstract = {BACKGROUND: The development of the COVID-19 vaccine, a groundbreaking scientific advancement, also fueled vaccine hesitancy mainly due to vaccine misinformation and the limited public understanding of the new technology and its rapid pace of development and deployment. A variety of public health communication strategies have been used that include engaging the community in identifying and developing messages, using culturally appropriate communication methods, applying behavioral health principles, and storytelling. The purpose of this scoping review was to assess the most relevant evidence from the research literature on storytelling interventions to mitigate COVID vaccine hesitancy during the pandemic.

METHODS: A scoping review was conducted using the PICOS framework and PRISMA-ScR guidelines, examining studies across 16 databases published between 2020 and October 2025.

RESULTS: Twelve studies met inclusion criteria. Studies involved diverse populations and four implementation themes (cultural relevance, emotional engagement, participant involvement and reach) were identified. The experimental and quasi-experimental studies consistently found that narratives elicited greater emotional engagement, heightened perceived credibility, and stronger identification with the messenger.

CONCLUSION: Storytelling is recognized as a critical component of public health campaigns in its ability to leverage the power of community influencers, such as religious leaders, educators, and local advocates who echo community values. Long-term cohort studies, community-based social marketing campaigns, and qualitative studies are needed to assess specific impacts on vaccination behaviors. Storytelling, when tailored to audience, culture, and context, can contribute to promotion of vaccination, particularly in improving trust, empathy, and misinformation.},
}

@article {pmid41380366,
year = {2025},
author = {Sorotos, M and Firmani, G and Mareş, T and Ceccaroni, A and Santanelli di Pompeo, F},
title = {Epidemiology of Breast Implant-Associated Anaplastic Large Cell Lymphoma - A systematic review of literature.},
journal = {Journal of plastic, reconstructive & aesthetic surgery : JPRAS},
volume = {113},
number = {},
pages = {399-410},
doi = {10.1016/j.bjps.2025.11.038},
pmid = {41380366},
issn = {1878-0539},
abstract = {INTRODUCTION: Breast Implant Associated - Anaplastic Large Cell Lymphoma (BIA-ALCL) cases are steadily increasing worldwide. When considering only the patients with textured implant as the active population, prevalence appears higher than previously reported, and uncertainty regarding incidence rate (IR) trends. We aimed to provide comprehensive estimates by identifying epidemiologic studies reporting prevalence, risk, and IR.

METHODS: A systematic review was conducted up to November 2024 across PubMed, Google Scholar, and Web of Science. Epidemiological data were extracted from the "Patient Registry and Outcomes for Breast Implants and Anaplastic Large Cell Lymphoma Etiology and Epidemiology" (PROFILE) registry (US-specific), Food and Drug Administration (FDA)-Medical Device Reporting (MDR) (US/global), and BIA-ALCL Global Network (worldwide), providing granular data for 2019-2024, enabling yearly IR analysis. All findings were normalized using textured implants patients as the denominator. Interrupted time-series analysis was used to determine the impact of the COVID-19 pandemic on BIA-ALCL reporting.

RESULTS: Among the 1949 studies, 23 were analyzed.

PREVALENCE: 1.0-397.9/100,000 persons; risk: 1:250-1:99,992; and IR 0.021-124/100.000 persons/year. Nationally (US), PROFILE and FDA-MDR data showed IR peaking in 2020 (16.4 and 25.7/100,000) and then declining. Globally, FDA-MDR estimates peaked in 2021 (0.95/100,000) and plummeted in 2022 (0.14/100,000). Global Network data peaked in 2018 (0.68/100,000), dropped in 2020 (0.18/100,000), but rose again in 2024 (0.73/100,000). Significant IR declines (p = 0.02), were identified during the COVID-19 pandemic (2020-2022). Global data suggest transient underreporting and diagnostic delays.

CONCLUSION: BIA-ALCL IR decreased in 2022, then rose globally in 2023-2024, but not in the US, where it continued declining. IR trends were increasing but were influenced by COVID-19, with differences in absolute values likely reflecting smooth vs. textured implant market share variations. Contextualizing epidemiology by surface type and geography remains fundamental.},
}

@article {pmid41379427,
year = {2025},
author = {Salamh, P and Dilibe-Daramola, F and Flannery, A and Pollard, C and Rocha, R and Lapidow, A and Wooten, L},
title = {Incidence and characteristics among individuals developing frozen shoulder following COVID-19 vaccine administration: A systematic review.},
journal = {Physiotherapy theory and practice},
volume = {},
number = {},
pages = {1-8},
doi = {10.1080/09593985.2025.2601894},
pmid = {41379427},
issn = {1532-5040},
abstract = {PURPOSE: Perform a systematic review to determine incidence and characteristics of vaccine administration of those developing frozen shoulder (FS) following COVID-19 vaccine administration.

METHODOLOGY: Systematic review of the literature (PROSPERO number CRD42024611140). Inclusion criteria; diagnosis of frozen shoulder, published or available in the English language and onset of frozen shoulder linked to COVID-19 vaccination. Studies were excluded if FS was linked to onset outside of vaccination and if data were not separated. Relevant studies were assessed for inclusion and selected studies were identified from PubMed, EMBASE, EBSCOhost, Cochrane Library, Web of Science and CINAHL databases. The search strategy was developed by a biomedical librarian run on August 4, 2025. Data were extracted from retained studies and underwent quality assessment using The Joanna Briggs Institute Critical Appraisal Checklist.

RESULTS: The search resulted in 1,506 studies and 9 retained for appraisal. A total of 140 individuals were identified among the retained studies with past medical history being reported in 6 of these studies identifying diabetes and hypothyroidism among the most common. Vaccine manufacturer and symptom manifestation data were reported in all retained studies. Incidence could not be determined based on available data.

CONCLUSION: In addition to known risk factors associated with vaccinations, those with comorbidities associated with the etiology of FS may also be predisposed to developing FS following COVID-19 vaccination administration. Clinicians evaluating those with suspected FS should be aware of the link between vaccinations and the development of FS. Additionally, clinicians administering COVID-19 vaccinations and boosters need to be aware of potential risk factors that may predispose individuals to developing FS following as well as possible signs and symptoms to be aware of post-vaccination.},
}

@article {pmid41379362,
year = {2025},
author = {Nazarian, E and Sinnige, JS and Bos, LDJ and Smit, MR},
title = {Advances in bedside imaging: lung ultrasound.},
journal = {Intensive care medicine experimental},
volume = {13},
number = {1},
pages = {126},
pmid = {41379362},
issn = {2197-425X},
abstract = {Lung ultrasound has become an indispensable tool in the management of acute respiratory failure, offering real-time, radiation-free bedside imaging. Its portability, repeatability, and high sensitivity for detecting pulmonary abnormalities have made it particularly valuable in critical care settings, especially during the Coronavirus disease 2019 pandemic. This narrative review explores the evolving role of lung ultrasound, examining both its established clinical applications and recent advances in artificial intelligence and imaging analysis. These developments emphasize the growing importance of lung ultrasound not only as a diagnostic tool but also as a platform for innovation, with artificial intelligence-driven approaches to further enhance its clinical utility.},
}

@article {pmid41223433,
year = {2025},
author = {Worthington, D},
title = {Integration of Virtual Care in the Audiology Service and Beyond.},
journal = {American journal of audiology},
volume = {34},
number = {4},
pages = {767-780},
doi = {10.1044/2025_AJA-25-00149},
pmid = {41223433},
issn = {1558-9137},
mesh = {Humans ; *Telemedicine/organization & administration ; COVID-19 ; *Audiology/organization & administration/methods ; United States ; United States Department of Veterans Affairs ; Pandemics ; SARS-CoV-2 ; Health Services Accessibility ; *Coronavirus Infections/epidemiology ; *Pneumonia, Viral/epidemiology ; Betacoronavirus ; },
abstract = {PURPOSE: This clinical focus article examines the history and evolution of telehealth, emphasizing its technological advancements, integration into health care systems, and the transformative impact of the COVID-19 pandemic on telehealth utilization in the United States, within the private sector and the Veterans Health Administration (VHA). Particular attention is given to the integration of audiology within telehealth, highlighting how the growth and use of teleaudiology services within the VHA have expanded access to this specialized care for Veterans. It aims to clarify how telehealth, including teleaudiology, has been established as a critical modality for enhancing health care access and delivery to Veterans.

CONCLUSIONS: The historical context reveals that, while telehealth has roots tracing back to the American Civil War or earlier, the COVID-19 pandemic catalyzed an unprecedented surge in adoption and integration of telehealth services in both the private sector and the VHA. The data indicate a significant increase in telehealth encounters and patient satisfaction before, during, and after the COVID-19 pandemic, reinforcing its role as a complementary modality alongside traditional in-person care. Challenges such as regulatory barriers and digital access disparities continue to exist, yet ongoing efforts to embed telehealth training in health care education and to foster technological innovation signal a promising future for telehealth. As the health care landscape evolves, telehealth is poised to remain an integral component of patient-centered care.},
}

Humans
*Telemedicine/organization & administration
COVID-19
*Audiology/organization & administration/methods
United States
United States Department of Veterans Affairs
Pandemics
SARS-CoV-2
Health Services Accessibility
*Coronavirus Infections/epidemiology
*Pneumonia, Viral/epidemiology
Betacoronavirus

@article {pmid41128286,
year = {2025},
author = {Ajulo, HK and Alele, FO and Emeto, TI and Adegboye, OA},
title = {Spatial and spatiotemporal machine learning models for COVID-19 dynamics: a review of methodology and reporting practices.},
journal = {Epidemiologic reviews},
volume = {47},
number = {1},
pages = {},
doi = {10.1093/epirev/mxaf017},
pmid = {41128286},
issn = {1478-6729},
mesh = {*COVID-19/epidemiology ; Humans ; *Machine Learning ; *Spatio-Temporal Analysis ; SARS-CoV-2 ; Pandemics ; },
abstract = {COVID-19 has transitioned from a pandemic to an endemic state, but the emergence of novel variants continues to pose significant public health challenges. In this study, the application of spatial and spatiotemporal machine learning (ML) models in understanding the dynamics of COVID-19 was systematically reviewed, as were contextual local-level comprehensive socio-environmental drivers. A systematic search was conducted across the Scopus, Web of Science, PubMed, Emcare (via Ovid), and the World Health Organization COVID-19 databases, and gray literature, adhering to Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Data extraction was conducted according to the Critical Appraisal and Data Extraction for Systematic Reviews of Prediction Modeling Studies checklist, and study quality was assessed using a validated scoring system. A total of 42 studies met the inclusion criteria. The review Findings indicate that global-scale spatial and spatiotemporal ML models dominate the field. Long-standing standalone factors in the demographic, environmental, and socioeconomic domains are frequently used as local-level drivers. However, the integration of composite indicators, aggregating multiple standalone factors into a single score, is notably lacking. Such composite indicators have the potential to reduce model complexity, improve interpretability, and enhance performance by capturing multidimensional aspects of vulnerability or risk in a more simplified form. This review highlights critical gaps in the current use of spatial and spatiotemporal ML models to understand the spatial epidemiology of COVID-19. Addressing these gaps could significantly enhance the understanding of COVID-19 dynamics and inform the development of effective public health strategies to mitigate future threats.},
}

*COVID-19/epidemiology
Humans
*Machine Learning
*Spatio-Temporal Analysis
SARS-CoV-2
Pandemics

@article {pmid41102611,
year = {2025},
author = {Karakonstantis, S and Lytras, T and Keske, S and Tsiodras, S and Papst, L and Ioannou, P and Velikov, P and Berg, LP and De Angelis, G and Prendki, V and Adlhoch, C and Penttinen, P and Rello, J and Gavazzi, G and Malhotra-Kumar, S and Skevaki, C and Slafkosky, M and Rath, B},
title = {The Care Continuum of Patients With Influenza in the Post-COVID-19 Era: A Position Paper.},
journal = {The Journal of infectious diseases},
volume = {232},
number = {Supplement_3},
pages = {S333-S346},
doi = {10.1093/infdis/jiaf333},
pmid = {41102611},
issn = {1537-6613},
mesh = {Humans ; *Influenza, Human/therapy/diagnosis ; *COVID-19/epidemiology ; *Continuity of Patient Care ; SARS-CoV-2 ; Health Services Accessibility ; },
abstract = {This position paper addresses the evolving care continuum for patients with respiratory viral infections in the context of the post-coronavirus disease 2019 pandemic phase. We emphasize the need to place the patient at the center of attention from the first signs of influenza-like illness to recovery. Current practices have revealed several deficiencies, such as timely access to healthcare, fragmentation of care, and inadequate follow-up instructions. This article proposes means to address these deficiencies and discusses diagnostic and management considerations for patients with suspected influenza infection.},
}

Humans
*Influenza, Human/therapy/diagnosis
*COVID-19/epidemiology
*Continuity of Patient Care
SARS-CoV-2
Health Services Accessibility

@article {pmid40982324,
year = {2025},
author = {Cruise, C},
title = {Overview of Telehealth in the Department of Veterans Affairs.},
journal = {American journal of audiology},
volume = {34},
number = {4},
pages = {781-784},
doi = {10.1044/2025_AJA-24-00274},
pmid = {40982324},
issn = {1558-9137},
mesh = {Humans ; *Telemedicine/organization & administration/trends ; United States ; *United States Department of Veterans Affairs ; COVID-19/epidemiology ; SARS-CoV-2 ; Health Services Accessibility ; Pandemics ; Veterans ; },
abstract = {BACKGROUND: Telehealth facilitates access to care via technology and broadband infrastructure, remotely connecting patients and their clinical care teams. This is particularly important for those in rural and medically underserved areas, where there may be a lack of specialty medical care, and terrain, weather, or transportation options may make travel to a health care facility difficult.

PURPOSE: The purpose of this clinical focus article is to provide an overview of the history, current state, and future direction of telehealth within the Department of Veterans Affairs.

CONCLUSIONS: A variety of tools and technology with which telehealth can be delivered exist. This enables health care organizations to leverage their clinical networks to match supply and demand across their enterprise and offer additional choices for how patients receive their care. The COVID-19 pandemic was an opportune time for expansion of telehealth. Postpandemic, in many health care systems, it has become a core part of clinical operations. To realize the full potential of telehealth and to ensure equity across populations, addressing gaps in broadband access and digital skills will be critical.},
}

Humans
*Telemedicine/organization & administration/trends
United States
*United States Department of Veterans Affairs
COVID-19/epidemiology
SARS-CoV-2
Health Services Accessibility
Pandemics
Veterans

@article {pmid40010790,
year = {2025},
author = {Chen, JG and Chen, CY and Zhu, K and Ren, XY and Li, HB},
title = {[Interpretation of the Position Paper on Olfactory Dysfunction 2023 (PPOD-23)].},
journal = {Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery},
volume = {60},
number = {2},
pages = {212-216},
doi = {10.3760/cma.j.cn115330-20240428-00246},
pmid = {40010790},
issn = {1673-0860},
support = {2024SF-YBXM-345//Key Research and Development Program of Shaanxi Province/ ; xzy012020046//Basic Research Fund for the Central Universities/ ; 2021JQ-418//Natural Science Foundation of Shaanxi Province Youth Project/ ; },
mesh = {Humans ; COVID-19 ; *Olfaction Disorders/diagnosis/therapy ; Pandemics ; SARS-CoV-2 ; *Coronavirus Infections/complications ; *Pneumonia, Viral ; Betacoronavirus ; Practice Guidelines as Topic ; },
}

Humans
COVID-19
*Olfaction Disorders/diagnosis/therapy
Pandemics
SARS-CoV-2
*Coronavirus Infections/complications
*Pneumonia, Viral
Betacoronavirus
Practice Guidelines as Topic

@article {pmid39905337,
year = {2025},
author = {Pennestrì, F and Cabitza, F and Picerno, N and Banfi, G},
title = {Sharing reliable information worldwide: healthcare strategies based on artificial intelligence need external validation. Position paper.},
journal = {BMC medical informatics and decision making},
volume = {25},
number = {1},
pages = {56},
pmid = {39905337},
issn = {1472-6947},
support = {Ricerca Corrente//Ministero della Salute/ ; },
mesh = {Humans ; *Artificial Intelligence ; *COVID-19 ; *Information Dissemination/methods ; *Machine Learning ; Reproducibility of Results ; SARS-CoV-2 ; },
abstract = {Training machine learning models using data from severe COVID-19 patients admitted to a central hospital, where entire wards are specifically dedicated to COVID-19, may yield predictions that differ significantly from those generated using data collected from patients admitted to a high-volume specialized hospital for orthopedic surgery, where COVID-19 is only a secondary diagnosis. This disparity arises despite the two hospitals being geographically close (within20 kilometers). While machine learning can facilitate rapid public health responses, rigorous external validation and continuous monitoring are essential to ensure reliability and safety.},
}

Humans
*Artificial Intelligence
*COVID-19
*Information Dissemination/methods
*Machine Learning
Reproducibility of Results
SARS-CoV-2

@article {pmid39610162,
year = {2024},
author = {Jacobsen, FF and Glasdam, S and Haukelien, H and van den Muijsenbergh, METC and Ågotnes, G},
title = {Healthy ageing in long-term care? Lessons learned from the COVID-19 pandemic: a position paper.},
journal = {Primary health care research & development},
volume = {25},
number = {},
pages = {e66},
pmid = {39610162},
issn = {1477-1128},
mesh = {Aged ; Aged, 80 and over ; Female ; Humans ; Male ; *COVID-19/epidemiology/prevention & control ; *Frail Elderly ; *Healthy Aging ; *Long-Term Care/organization & administration ; Nursing Homes ; Pandemics ; SARS-CoV-2 ; },
abstract = {AIM: This position paper focuses on healthy ageing for the frailest and institutionalized older adults in the context of the recent pandemic. The paper aims to identify and discuss hindering and promoting factors for healthy ageing in this context, taking both health safety and a meaningful social life into account, in a pandemic situation and beyond.

BACKGROUND: The recent COVID-19 pandemic has highlighted the vulnerability of frail older adults residing in long-term care institutions. This is a segment of the older population that does not seem to align well with the recent policy trend of healthy and active ageing. The need for healthy ageing in this population has been voiced by professionals and interest organizations alike, alluding to inadequate support systems during the pandemic, conditioned by both previous and newly emerging contextual factors. Supporting healthy ageing in older adults in nursing homes and other residential care settings calls for attending to meaningful social life as well as to disease control.

METHODS: Findings and early conclusions leading up to the position paper were presented with peer discussions involving healthcare professionals and researchers at two joint EFPC PRIMORE workshops 2021 and 2022, as well as other international research seminars on long-term care. The following aspects of long-term care and COVID-19 were systematically discussed in those events, with reference to relevant research literature: 1. Long-term care policies, 2. pre-COVID state of long-term care facilities and vulnerability to the pandemic, 3. factors influencing the extent of spread of infection in long-term care facilities, and 4. the challenge of balancing between strict measures for infection control and maintaining a meaningful social life for residents and their significant others.

FINDINGS: A policy shift towards ageing at home and supporting the healthiest of older adults seems to have had unwarranted effects both for frail older adults, their significant others, and professional care staff attending to their needs. Resulting insufficient investment in primary health care staff and in the built environment for frail older adults in nursing homes were detrimental both for the older adults living in nursing homes, their significant others, and staff. More investment in staff and in physical surroundings might improve the quality of care and the social life of older adults in nursing homes in a non-pandemic situation and be a resource for primary health care staff ensuring both protection from health hazards and a meaningful social life for frail older adults in a pandemic or epidemic situation. As for investing in the physical surroundings, smaller nursing homes are advantageous, with singular resident rooms and for developing out-and indoor spaces for socializing and for meeting with families and other visitors. Regarding investment in staff, there is a documented need for educated staff in full-time positions. Use of part-time or temporary staff should be limited.},
}

Aged
Aged, 80 and over
Female
Humans
Male
*COVID-19/epidemiology/prevention & control
*Frail Elderly
*Healthy Aging
*Long-Term Care/organization & administration
Nursing Homes
Pandemics
SARS-CoV-2

@article {pmid39441539,
year = {2025},
author = {Vohra, KP and Johnson, KG and Dalal, A and Ibrahim, S and Krishnan, V and Abbasi-Feinberg, F and Abreu, AR and Bandyopadhyay, A and Gurubhagavatula, I and Kuhlmann, D and Martin, JL and Olson, EJ and Patil, SP and Shelgikar, AV and Trotti, LM and Wickwire, EM and Rowley, JA and Kapur, VK},
title = {Recommendations for permanent sleep telehealth: an American Academy of Sleep Medicine position statement.},
journal = {Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine},
volume = {21},
number = {2},
pages = {401-404},
pmid = {39441539},
issn = {1550-9397},
mesh = {Humans ; *Telemedicine/standards ; United States ; *Sleep Medicine Specialty ; *COVID-19/epidemiology ; *Sleep Wake Disorders/therapy ; Societies, Medical ; Academies and Institutes ; },
abstract = {UNLABELLED: Telehealth use greatly expanded under the Centers for Medicare and Medicaid Services waivers at the start of the COVID-19 pandemic; however, the uncertainty and limitations of continued coverage risks loss of this momentum. Permanent coverage with adequate reimbursement is essential for the long-term acceptance and expansion of telehealth services. Telehealth supports both the current and future need for sleep health management by expanding patient access, increasing clinician efficiency, improving patient safety, and addressing health care equity. Sleep medicine is an ideal field for telehealth due to limited provider access, safety concerns with sleepy patients, availability of remote patient monitoring for treatment management, and the minimal need for repeated physical examinations. Telehealth is noninferior for delivery of cognitive behavioral therapy for insomnia and can enhance obstructive sleep apnea treatment adherence. It is the position of the American Academy of Sleep Medicine that telehealth is an essential tool for the provision of high-quality, patient-centered care for patients with sleep disorders. We encourage all stakeholders including legislators, policymakers, clinicians, and patients to work together to address payment models, interstate care, technology access, prescribing practices, and ongoing research to ensure that sleep telehealth services are permanently available and accessible for all patients seeking sleep medicine care.

CITATION: Vohra KP, Johnson KG, Dalal A, et al. Recommendations for permanent sleep telehealth: an American Academy of Sleep Medicine position statement. J Clin Sleep Med. 2025;21(2):401-404.},
}

Humans
*Telemedicine/standards
United States
*Sleep Medicine Specialty
*COVID-19/epidemiology
*Sleep Wake Disorders/therapy
Societies, Medical
Academies and Institutes

@article {pmid39321629,
year = {2024},
author = {Assiri, AM and Alshahrani, AM and Sakkijha, H and AlGeer, A and Zeitouni, M and AlGohary, M and Dhaini, L and Verma, R and Singh, H},
title = {Transforming respiratory tract infection diagnosis in the kingdom of saudi arabia through point-of-care testing: A white paper for policy makers.},
journal = {Diagnostic microbiology and infectious disease},
volume = {110},
number = {4},
pages = {116530},
doi = {10.1016/j.diagmicrobio.2024.116530},
pmid = {39321629},
issn = {1879-0070},
mesh = {Humans ; COVID-19/diagnosis/epidemiology ; Health Policy ; *Point-of-Care Testing/organization & administration ; *Respiratory Tract Infections/diagnosis/drug therapy/epidemiology ; Saudi Arabia/epidemiology ; },
abstract = {With the evident increased prevalence of respiratory tract infections (RTIs) such as Respiratory Syncytial Virus (RSV), influenza, Group A Streptococcus (GAS), and COVID-19, the conventional diagnostic methods are considered sub-optimal in providing timely management to patients in the Kingdom of Saudi Arabia (KSA). Gaps in current diagnostics are magnified by the Kingdom's unique demographic composition, comprising 11.9 million foreign workers, and the annual influx of over 10 million pilgrims. Current gaps in timely diagnosis leads to delays in treatment, misuse of antibiotics, and protracted hospital stays, subsequently compromising patient care, and escalating healthcare costs. KSA healthcare stakeholders suggest that the integration of rapid molecular Point-of-Care Testing (POCT) into the Kingdom's healthcare infrastructure is an absolute necessity. This publication serves as an urgent call for action aimed at healthcare policymakers in Saudi Arabia, to review the existing diagnostic challenges and include rapid POCTs in the Saudi healthcare strategy for respiratory infections.},
}

Humans
COVID-19/diagnosis/epidemiology
Health Policy
*Point-of-Care Testing/organization & administration
*Respiratory Tract Infections/diagnosis/drug therapy/epidemiology
Saudi Arabia/epidemiology

@article {pmid39074368,
year = {2024},
author = {Snyder Sulmasy, L and Burnett, JR and Carney, JK and DeCamp, M and , },
title = {Ethics and Academic Discourse, Scientific Integrity, Uncertainty, and Disinformation in Medicine: An American College of Physicians Position Paper.},
journal = {Annals of internal medicine},
volume = {177},
number = {9},
pages = {1244-1250},
doi = {10.7326/M24-0648},
pmid = {39074368},
issn = {1539-3704},
mesh = {Humans ; *COVID-19 ; Uncertainty ; *SARS-CoV-2 ; *Ethics, Medical ; *Pandemics ; United States ; Communication ; Pneumonia, Viral ; Betacoronavirus ; },
abstract = {Respect for the scientific process and a diversity of views; open discourse and debate based on principles of ethics, best available evidence, and scientific inquiry and integrity; and an understanding of evidence gaps and uncertainty and how to communicate about them are important values in the advancement of science and the practice of medicine. Physicians often must make decisions about their recommendations to patients in the face of scarce or conflicting data. Are these characteristics of medicine and science widely understood and effectively communicated among members of the profession and to patients and the public? Issues of scientific integrity are longstanding, but COVID-19 brought them to the forefront, in an environment that was sometimes characterized by communication missteps as guidance came and went-or changed-quickly. Today, is open debate flourishing? Have some debates shed more heat than light? Are people losing confidence in science and medicine? In health care institutions? The American College of Physicians explores these issues and offers guidance in this position paper.},
}

Humans
*COVID-19
Uncertainty
*SARS-CoV-2
*Ethics, Medical
*Pandemics
United States
Communication
Pneumonia, Viral
Betacoronavirus

@article {pmid39028203,
year = {2024},
author = {Hsu, VP and Pergam, SA and Shenoy, ES and Banach, DB and Jones Batshon, L and Branch-Elliman, W and Dumyati, G and Haessler, S and Jump, RLP and Malani, AN and Mathew, TA and Murthy, RK and Weber, DJ},
title = {SHEA position statement on pandemic preparedness for policymakers: emerging infectious threats.},
journal = {Infection control and hospital epidemiology},
volume = {45},
number = {7},
pages = {818-820},
doi = {10.1017/ice.2024.64},
pmid = {39028203},
issn = {1559-6834},
mesh = {Humans ; *Pandemics/prevention & control ; Communicable Diseases, Emerging/prevention & control/epidemiology ; COVID-19/prevention & control/epidemiology ; Disaster Planning/organization & administration ; Health Policy ; Pandemic Preparedness ; },
}

Humans
*Pandemics/prevention & control
Communicable Diseases, Emerging/prevention & control/epidemiology
COVID-19/prevention & control/epidemiology
Disaster Planning/organization & administration
Health Policy
Pandemic Preparedness