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About | Classical Genetics | Timelines | What's New | What's Hot

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The Electronic Scholarly Publishing Project: Providing access to classic scientific papers and other scholarly materials, since 1993. More About:  ESP | OUR CONTENT | THIS WEBSITE | WHAT'S NEW | WHAT'S HOT

ESP Timelines

Comparative Timelines

The ESP Timeline (one of the site's most popular features) has been completely updated to allow the user to select (using the timeline controls above each column) different topics for the left and right sides of the display.

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image The numerical equality of paternal and maternal chromosomes at fertilization was established by Theodor Boveri and Jean-Louis-Léon Guignard.

1890

image The numerical equality of paternal and maternal chromosomes at fertilization was established by Theodor Boveri and Jean-Louis-Léon Guignard.

(no entry for this year)

1891

(no entry for this year)

image Publication of August Weismann's book Das Keimplasma (The Germ Plasm) emphasized meiosis as an exact mechanism of chromosome distribution.

Joseph Whiteaves describes Anomalocaris, meaning "anomalous shrimp," from the Cambrian. The fossil that Whiteaves identifies as a shrimp will later prove to be part of a much larger animal.

1892

image Publication of August Weismann's book Das Keimplasma (The Germ Plasm) emphasized meiosis as an exact mechanism of chromosome distribution.

Joseph Whiteaves describes Anomalocaris, meaning "anomalous shrimp," from the Cambrian. The fossil that Whiteaves identifies as a shrimp will later prove to be part of a much larger animal.

Entomologist E.B. Poulton studies caterpillars from the species Gastropacha quercifolia, noting how siblings look different depending on where they live and what they eat. His discovery will become known as phenotypic plasticity.

1893

Entomologist E.B. Poulton studies caterpillars from the species Gastropacha quercifolia, noting how siblings look different depending on where they live and what they eat. His discovery will become known as phenotypic plasticity.

image Wilhelm Wien discovers that the maximum wavelength emitted by hot body varies inversely with its absolute temperature. Wien's law becomes useful in establishing the temperature of stars. The problems he has with deriving an equation to describe black-body radiation lead to Max Planck's introduction of the quantum in 1900.

image Hans Driesch expounded the view that all nuclei of an organism were equipotential but varied in their activity in accordance with the differentiation of tissues.

image Karl Pearson published the first in a long series of contributions to the mathematical theory of evolution. Methods for analyzing statistical frequency distributions were developed in detail.

image William Bateson's Materials for the Study of Variation emphasized the importance of discontinuous variations, foreshadowing the rediscovery of Mendel's work.

Eugène Dubois publishes his monograph of Pithecanthropus erectus, or Java Man, a missing link between humans and apes.

French paleontologist Charles Brongniart describes a fossil dragonfly from the Carboniferous with a 2-foot (63-centimeter) wingspan. The find implies a higher oxygen content in the Earth's ancient atmosphere.

image The intricately carved mammoth ivory figurine known as the Lady (or Venus) of Brassempouy is discovered in France. At roughly 25,000 years old, it ranks among the earliest known depictions of a human face.

1894

image Hans Driesch expounded the view that all nuclei of an organism were equipotential but varied in their activity in accordance with the differentiation of tissues.

image Karl Pearson published the first in a long series of contributions to the mathematical theory of evolution. Methods for analyzing statistical frequency distributions were developed in detail.

image William Bateson's Materials for the Study of Variation emphasized the importance of discontinuous variations, foreshadowing the rediscovery of Mendel's work.

Eugène Dubois publishes his monograph of Pithecanthropus erectus, or Java Man, a missing link between humans and apes.

French paleontologist Charles Brongniart describes a fossil dragonfly from the Carboniferous with a 2-foot (63-centimeter) wingspan. The find implies a higher oxygen content in the Earth's ancient atmosphere.

image The intricately carved mammoth ivory figurine known as the Lady (or Venus) of Brassempouy is discovered in France. At roughly 25,000 years old, it ranks among the earliest known depictions of a human face.

image Joseph John (J.J.) Thomson announces that he has found that the velocity of cathode rays is much lower than that of light.

A team of paleontologists, including Samuel Williston, Elmer Riggs and Barnum Brown, successfully excavates a Triceratops fossil in Wyoming.

1895

A team of paleontologists, including Samuel Williston, Elmer Riggs and Barnum Brown, successfully excavates a Triceratops fossil in Wyoming.

image Charles Thomson Rees Wilson develops the CLOUD CHAMBER, a box containing a gas that is saturated. When a charged particle passes through the gas, small droplets are formed that make the track of the particle visible. The cloud chamber becomes a powerful tool in particle physics.

image Pierre Curie shows that as the temperature of the magnet is increased, there is a level at which the magnetism is disrupted and ceases to exist. This temperature is still called the Curie point.

image Wilhelm Konrad Röntgen (Roentgen) discovers X-rays, which will soon be applied in the visualization of bodily structures and in the induction of genetic mutations (both intentionally and accidentally).

image E. B. Wilson publishes The Cell in Development and Heredity. This influential treatise (ultimately reprinted in several editions) distills the information compiled concerning cytology in the half-century since Schleiden and Schwann put forth the cell theory.

Dublin anatomist Daniel Cunningham concludes that Neanderthals represent an intermediate step between Pithecanthropus erectus and modern humans.

J. de Morgan describes nine pierced fossil urchins found in a Chalcolithic tomb at Toukh.

1896

image E. B. Wilson publishes The Cell in Development and Heredity. This influential treatise (ultimately reprinted in several editions) distills the information compiled concerning cytology in the half-century since Schleiden and Schwann put forth the cell theory.

Dublin anatomist Daniel Cunningham concludes that Neanderthals represent an intermediate step between Pithecanthropus erectus and modern humans.

J. de Morgan describes nine pierced fossil urchins found in a Chalcolithic tomb at Toukh.

image Less than three months after the discovery of x-rays, Dartmouth College Professor of Physics Edwin Frost and his brother, the then physician in chief of Mary Hitchcock Hospital, Gilman Frost, MD, take the first clinical X-ray in the US — an image of Eddie McCarthy's fractured left wrist.

image Antoine-Henri Becquerel discovers rays produced by uranium — the first observation of natural radioactivity.

image Gabriel Bertrand coined the term COENZYME to designate inorganic substances which were necessary to activate certain enzymes.

1897

image Gabriel Bertrand coined the term COENZYME to designate inorganic substances which were necessary to activate certain enzymes.

Renowned physicist Lord Kelvin gives a lecture at London's Victoria Institute claiming that the sun, which is cooling from its initial formation, can be no more than 20 million years old.

image Joseph John Thomson discovers the electron, the first known particle that is smaller than an atom, in part because he has better vacuum pumps that were previously available. He, and independently, Emil Wiechert, determine the ratio of mass to charge of the particles by deflecting them by electric and magnetic fields.

Marie Curie begins research of "uranium rays" that will lead to the discovery of radioactivity.

(no entry for this year)

1898

image image Marie and Pierre Curie discovered that thorium, gives off "uranium rays", which Marie renames RADIOACTIVITY.

image image L. Cuénot (France) working with animals, and Strasburger (Germany) working with plants, advance theory that sex is controlled within the germ cell, not by environment.

Richard Altmann renames "nuclein" as NUCLEIC ACID.

The First International Congress of Genetics held in London.

image William Bateson writes a paper on hybridisation and cross-breeding as a method of scientific investigation that anticipates Mendel's rediscovery.

1899

image British physicist Ernest Rutherford discovers the radioactivity from uranium has at least two different forms, which he calls alpha and beta rays.

image image image Fritz Geisel, Antoine-Henri Becquerel, and Marie Curie proved the beta rays consist of high-speed electrons.

image image L. Cuénot (France) working with animals, and Strasburger (Germany) working with plants, advance theory that sex is controlled within the germ cell, not by environment.

Richard Altmann renames "nuclein" as NUCLEIC ACID.

The First International Congress of Genetics held in London.

image William Bateson writes a paper on hybridisation and cross-breeding as a method of scientific investigation that anticipates Mendel's rediscovery.

ESP Quick Facts

ESP Origins

In the early 1990's, Robert Robbins was a faculty member at Johns Hopkins, where he directed the informatics core of GDB — the human gene-mapping database of the international human genome project. To share papers with colleagues around the world, he set up a small paper-sharing section on his personal web page. This small project evolved into The Electronic Scholarly Publishing Project.

ESP Support

In 1995, Robbins became the VP/IT of the Fred Hutchinson Cancer Research Center in Seattle, WA. Soon after arriving in Seattle, Robbins secured funding, through the ELSI component of the US Human Genome Project, to create the original ESP.ORG web site, with the formal goal of providing free, world-wide access to the literature of classical genetics.

ESP Rationale

Although the methods of molecular biology can seem almost magical to the uninitiated, the original techniques of classical genetics are readily appreciated by one and all: cross individuals that differ in some inherited trait, collect all of the progeny, score their attributes, and propose mechanisms to explain the patterns of inheritance observed.

ESP Goal

In reading the early works of classical genetics, one is drawn, almost inexorably, into ever more complex models, until molecular explanations begin to seem both necessary and natural. At that point, the tools for understanding genome research are at hand. Assisting readers reach this point was the original goal of The Electronic Scholarly Publishing Project.

ESP Usage

Usage of the site grew rapidly and has remained high. Faculty began to use the site for their assigned readings. Other on-line publishers, ranging from The New York Times to Nature referenced ESP materials in their own publications. Nobel laureates (e.g., Joshua Lederberg) regularly used the site and even wrote to suggest changes and improvements.

ESP Content

When the site began, no journals were making their early content available in digital format. As a result, ESP was obliged to digitize classic literature before it could be made available. For many important papers — such as Mendel's original paper or the first genetic map — ESP had to produce entirely new typeset versions of the works, if they were to be available in a high-quality format.

ESP Help

Early support from the DOE component of the Human Genome Project was critically important for getting the ESP project on a firm foundation. Since that funding ended (nearly 20 years ago), the project has been operated as a purely volunteer effort. Anyone wishing to assist in these efforts should send an email to Robbins.

ESP Plans

With the development of methods for adding typeset side notes to PDF files, the ESP project now plans to add annotated versions of some classical papers to its holdings. We also plan to add new reference and pedagogical material. We have already started providing regularly updated, comprehensive bibliographies to the ESP.ORG site.

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Timeline

The new, dynamic Timeline from the Electronic Scholarly Publishing Project gives users more control over the timeline display.

We seek your suggestions for timeline content, both for individual events and for entire subjects.

To submit a correction or a recommendation or to propose new Timeline content (or to volunteer as a Timeline Editor), click HERE.

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ESP Picks from Around the Web (updated 06 MAR 2017 )