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The ESP Timeline (one of the site's most popular features) has been completely updated to allow the user to select (using the timeline controls above each column) different topics for the left and right sides of the display.
New Left Column
New Left Column
New Right Column
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Commodore releases the Amiga 3000
Hubble Space Telescope uses 386 processor
Introduction of IBM RS/6000
Microsoft launches Windows 3.0
The Human Genome Project is launched with the goal of sequencing all 3 billion base pairs of human DNA by 2005.
Mongolia invites the American Museum of Natural History to reinstate excavations in the Gobi desert.
Scott Wing of the Smithsonian Institution discovers the Big Cedar Ridge fossil plant site in Wyoming. The locality will become known as the Pompeii of Cretaceous plants.
Apple releases the PowerBook 100
First E-mail From Space Is Sent from a Mac Portable
Linus Torvalds from Finland releases Linux version 0.02
Silicon & Synapse founded
Sun Microsystems Starts Java Technology
Chicxulub crater is discovered in the Yucatán Peninsula, supporting the asteroid impact theory first suggested in 1980.
Commodore releases the the Amiga 500+
Internet freed from Government control
Microsoft Releases Windows 3.1
Photo CD created by Kodak.
A team led by Tim White finds the first traces of a hominid fossil that will later be named Ardipithecus ramidus. Seventeen years later, the team will publish a detailed description of a 4.4-million-year-old, 120-centimeter-tall, nearly complete adult female, along with fossils from 35 other individuals. The team will argue that "Ardi" should supplant Lucy at the base of the hominid tree.
Ian Campbell and collaborators publish a paper pointing to the Siberian Traps, an area of massive volcanic activity, as the cause of the Permo- Triassic mass extinction 251 million years ago.
Paleontologists led by Jim Kirkland discover Utahraptor, a super-sized velociraptor that conveniently supports the super-sized velociraptors that will appear in the screen version of Jurassic Park a year later.
Suburban San Diego roadwork uncovers mastodon bones and broken rocks at what becomes known as the (Richard) Cerutti Mastodon site. Roadwork halts while paleontologist Tom Deméré examines the find. Twenty-five years later, Deméré, Cerutti and nine other researchers will contend that the site is evidence of human presence in North America 130,000 years ago.
Apple Newton Message Pad announced
Commodore released the CD32 model
Compaq Introduces Presario
Foundation of Nvidia
IBM Announces a loss of $4.97m for 1992
Intel Ships "Pentium" Chip"
Introduction of Apple Newton PDA
The Jet Propulsion Laboratory begins work on image-capturing devices using CMOS or active pixel sensors.
Kary Mullis and Michael Smith share a Nobel Prize in Chemistry, with Mullis cited for his contributions to the developments of methods within DNA-based chemistry and Smith for his fundamental contributions to the establishment of oligonucleiotide-based, site-directed mutagenesis and its development for protein studies.
Richard J. Roberts, and Phillip A. Sharp share a Nobel Prize in Medicine for their discoveries of split genes.
A calcite-encrusted hominid skeleton is discovered in a karst cave near Altamura, Italy. About two decades later, researchers will date the rock layers and test a scapula fragment, eventually concluding that the skeleton is probably 128,000 to 187,000 years old, and ranks among so- called "early Neanderthals."
Geology student Iwan Stossel stumbles across a nearly 400-million-year-old tetrapod fossil trackway on the island of Valentia, County Kerry, Ireland.
J. William Schopf publishes a description of microfossils of the Apex Basalt in Australia. His claims that they are 3.5-billion-year-old microbes that could photosynthesize and produce oxygen will later be challenged. One of his challengers, Martin Brasier, will coauthor a 2011 study on microfossils from a nearby outcrop, claiming that the 3.4-billion- year-old microbes fed off sulfur.
On an expedition in the Gobi desert, paleontologists from the American Museum of Natural History discover the skeleton of an Oviraptor dinosaur crouching over a nest of eggs, apparently incubating them in the same fashion as modern birds.
Roland Anderson and Jennifer Mather publish "Personalities of Octopuses" in the Journal of Comparative Psychology.
Netscape Communications Corporation is founded
Silicon & Synapse changes its name to Blizzard Entertainment
Yahoo founded January 1994
Nikon introduces the first optical-stabilized lens.
Anthropologist Ron Clarke finds previously overlooked foot bones, showing both ape and human qualities, from Sterkfontein. Future finds will associate these bones with a skeleton nicknamed Little Foot.
In what will later be named Chauvet Cave, French cavers discover 32,000-year-old paintings showing 400 animal images.
Microsoft launches Windows 95
Nvidia's NV1 launched
"Kodak DC40 and the Apple QuickTake 100 become the first digital cameras marketed for consumers."
Edward B. Lewis, Christiane Nüsslein-Volhard, and Eric F. Wieschaus share a Nobel Prize in Medicine for their discoveries concerning the genetic control of early embryonic development.
Lee Berger and Ron Clarke publish an article in the Journal of Human Evolution arguing that the Taung child, discovered in 1924, may have been killed by a bird of prey.
Apple Computer buys NeXT
eBay is founded by Jeff Skoll and Pierre Omidyar
Eastman Kodak, FujiFilm, AgfaPhoto, and Konica introduce the Advanced Photo System (APS).
Using "molecular clock" estimates of mutation rates, Greg Wray and collaborators hypothesize that metazoan phyla diverged from each other 1 billion years ago, or even earlier. In other words, they argue that metazoans existed hundreds of millions of years before the earliest metazoan fossils (about 600 million years old) yet found.
Alan Walker and Pat Shipman publish a description of advanced Vitamin A poisoning in a 1.7-million-year-old Homo erectus skeleton. They assert that it is evidence of both meat eating, caused by consuming the liver of a large carnivore, and sufficient sociability in Homo erectus to care for an ill and incapacitated individual.
Chen Pei Ji unveils Sinosauropteryx prima from Liaoning, China, the first feathered dinosaur discovered, at the Society of Vertebrate Paleontology's annual meeting. Fourteen years later, a team of Chinese and British paleontologists will argue that this animal had a striped tail, a reddish color alternating with white, based on pigment-rich microscopic spheres in the fossilized feathers.
The roughly 9,000-year-old Kennewick Man skeleton is found in the northwestern United States. Craniometric analysis initially suggests an affiliation to Ainu and Polynesian groups. Better DNA sampling methods will finally allow genetic analysis nearly 20 years later, and that will indicate a relationship closest to modern Native Americans.
Tim White's team discovers horse, antelope and other mammal bones with cut marks from stone tools — evidence of tool use 2.5 million years ago.
IBM's Deep Blue Beats Gary Kasparov at Chess
IBM announces RS/6000 SP Deep Blue
zon.com, an online bookseller, goes public
first known publicly shared picture via a cell phone, by Philippe Kahn.
A team of archaeologists finds evidence of human occupation 14,000 years ago at Monte Verde, Chile, pushing back the arrival date of humans in the Americas.
Excavations near Koblenz in northern Germany turn up a Neanderthal skullcap, estimated at 170,000 years old, that was apparently used as a bowl.
Paleontologist Karen Chin receives a 17-inch coprolite excavated in Saskatchewan. Estimated at 65 million years old and full of crunched bone, it is likely the calling card of a T. rex.
Paleontologist Paul Sereno discovers the delicate Darth Vader-like skull of a dinosaur he will later name Nigersaurus taqueti and nickname the "Mesozoic Cow."
Two 5-foot-long Humboldt squid in the Sea of Cortez "mug" a diver working on a PBS documentary, making off with the gold chain hanging around the diver's neck, and demonstrating that Humboldt squid have bad manners but good taste.
Apple Release the iMac
Foundation of Google by Larry Page and Sergey Brin
Introduction of Apple iMac
Microsoft launches Windows 98
Andrew Parker publishes a paper suggesting that some Cambrian animals (Wiwaxia, Canadia and Marella) developed flickering displays of iridescent color at about the same time that eyes evolved.
Aterian artifacts (named for stone tools discovered in Algeria in 1917) are estimated at 70,000 years old at sites in Libya. Over the next dozen years, the age of artifacts found at various sites in northern Africa will be pushed back to at least 110,000 years old.
Xiao, Zhang and Knoll describe fossilized animal embryos in Nature. Li, Chen and Hua simultaneously describe embryos in Science. The fossils all come from the Doushantuo phosphorites in southern China, and all are estimated to be about 570 million years old, making them the oldest fossil embryos so far discovered. Nine years later, however, Bailey and collaborators will challenge this interpretation, arguing the "fossil embryos" could just as easily be large bacteria. That challenge will be answered by the announcement of fossil embryos inside egg cysts.
Napster the first file sharing program introduced
Nvidia releases GeForce 256
The Millennium bug is taken seriously
Chinese paleontologists discover an exceptionally well-preserved feathered dinosaur, probably a juvenile dromaeosaur. Citing the confusion caused by language barriers and jet lag, the paleontologists' American collaborators nickname the fossil "Dave the fuzzy raptor," after a character alluded to in a Cheech and Chong routine. This fossil will be assigned to the genus Sinornithosaurus. (The next fuzzy discovery will be nicknamed "Chong.")
ESP Quick Facts
In the early 1990's, Robert Robbins was a faculty member at Johns Hopkins, where he directed the informatics core of GDB — the human gene-mapping database of the international human genome project. To share papers with colleagues around the world, he set up a small paper-sharing section on his personal web page. This small project evolved into The Electronic Scholarly Publishing Project.
In 1995, Robbins became the VP/IT of the Fred Hutchinson Cancer Research Center in Seattle, WA. Soon after arriving in Seattle, Robbins secured funding, through the ELSI component of the US Human Genome Project, to create the original ESP.ORG web site, with the formal goal of providing free, world-wide access to the literature of classical genetics.
Although the methods of molecular biology can seem almost magical to the uninitiated, the original techniques of classical genetics are readily appreciated by one and all: cross individuals that differ in some inherited trait, collect all of the progeny, score their attributes, and propose mechanisms to explain the patterns of inheritance observed.
In reading the early works of classical genetics, one is drawn, almost inexorably, into ever more complex models, until molecular explanations begin to seem both necessary and natural. At that point, the tools for understanding genome research are at hand. Assisting readers reach this point was the original goal of The Electronic Scholarly Publishing Project.
Usage of the site grew rapidly and has remained high. Faculty began to use the site for their assigned readings. Other on-line publishers, ranging from The New York Times to Nature referenced ESP materials in their own publications. Nobel laureates (e.g., Joshua Lederberg) regularly used the site and even wrote to suggest changes and improvements.
When the site began, no journals were making their early content available in digital format. As a result, ESP was obliged to digitize classic literature before it could be made available. For many important papers — such as Mendel's original paper or the first genetic map — ESP had to produce entirely new typeset versions of the works, if they were to be available in a high-quality format.
Early support from the DOE component of the Human Genome Project was critically important for getting the ESP project on a firm foundation. Since that funding ended (nearly 20 years ago), the project has been operated as a purely volunteer effort. Anyone wishing to assist in these efforts should send an email to Robbins.
With the development of methods for adding typeset side notes to PDF files, the ESP project now plans to add annotated versions of some classical papers to its holdings. We also plan to add new reference and pedagogical material. We have already started providing regularly updated, comprehensive bibliographies to the ESP.ORG site.
ESP Picks from Around the Web (updated 06 MAR 2017 )
CRISPR-Cas: Bringing precise editing to DNA manipulation.
Treating Disease with Fecal Transplantation
Fossils of miniature humans (hobbits) discovered in Indonesia
Science Policy & Funding
Overbuilding Research Capacity: an important editorial in which Bruce Alberts argues that the current funding trajectory is unsustainable.
Rescuing US biomedical research from its systemic flaws: Bruce Alberts and others argue that "it is time to rethink some fundamental features of the US biomedical research ecosystem."
Gates Foundation research can't be published in top journals
DNA barcoding shows that restaurant seafood is often not what it seems
Dinosaur tail, complete with feathers, found preserved in amber.
Dinosaurs and Feathers: A Bibliography
Mysterious fast radio burst (FRB) detected in the distant universe.
Colliding stars will light up the night sky in 2022
Big Data & Informatics
Big Data: Buzzword or Big Deal?
Hacking the genome: Identifying anonymized human subjects using publicly available data.
Using DNA as a mass-storage device for digital data.